Standout Papers
Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Interaction of caffeine with the GABAA receptor complex: alterations in receptor function but not ligand binding
1989
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 StandoutNobel
Elicited hippocampal theta rhythm: a screen for anxiolytic and procognitive drugs through changes in hippocampal function?
2007
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
Purification and partial characterization of goose ceruloplasmin
1988
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Synergism by caffeine and by cocaine of the motor control deficit produced by midazolam
1991
Caffeine: Implications of recent research for clinical practice.
1984
Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis
1998
Reversal of pathological pain through specific spinal GABAA receptor subtypes
2008 Nature
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
1990 StandoutNature
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+
1990 StandoutNobel
Caffeine-diazepam interaction and local cerebral glucose utilization in the conscious rat
1987
GABA A -receptors: Structural requirements and sites of gene expression in mammalian brain
1990
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
2008 StandoutNobel
Anticonvulsant activity of carbamazepine and N6-L-phrnylisopropyladenosine in rabbits. Relationship to adenosine receptors in central nervous system
1988
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone
1992
Caffeine-induced anxiety and increase of Kynurenine concentration in plasma of healthy subjects: A pilot study
1991
Differential distribution of exogenous BDNF, NGF, and NT‐3 in the brain corresponds to the relative abundance and distribution of high‐affinity and low‐affinity neurotrophin receptors
1995
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Functional properties of recombinant rat GABAA receptors depend upon subunit composition
1990 StandoutNobel
Direct evidence for the stimulation of rabbit retina dopamine receptors by ergot alkaloids
1976
Major Depressive Disorder
2008 Standout
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
1995 StandoutNobel
Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications
1987
Surgery for Seizures
1996 Standout
The Relative Contributions of MRI, SPECT, and PET Imaging in Epilepsy
1994
GABAergic dysfunction in mood disorders
2003
Molecular Basis of Buspirone's Anxiolytic Action
1991
Caffeine-induced anxiogenesis: The role of adenosine, benzodiazepine and noradrenergic receptors
1989
Effects of ergots on adenylate cyclase activity in the corpus striatum and pituitary
1977
A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis
1994 Standout
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects
1992 Standout
Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice
1996 StandoutNobel
Path integration and the neural basis of the 'cognitive map'
2006 StandoutNobel
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
The diversity of GABAA receptors
1998
Spontaneous Intracerebral Hemorrhage
2001 Standout
Two dopamine receptors: Biochemistry, physiology and pharmacology
1984
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
1998 StandoutNobel
Iron Catalysis in Organic Synthesis
2015 Standout
Iron(III)-catalyzed synthesis of multi-substituted imidazoles via [3+2] cycloaddition reaction of nitroolefins and N-aryl benzamidines
2013
Caffeine induced changes in cerebral circulation.
1985
Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
1980
Anxiety and caffeine consumption in people with anxiety disorders
1985
Multicopper Oxidases and Oxygenases
1996 Standout
Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.
1990
‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors
1986
Depression: a new animal model sensitive to antidepressant treatments
1977 StandoutNature
Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals
1981 Standout
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.
1989 StandoutNobel
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
1989 StandoutNature
The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans
1984
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
Urinary and brain beta-carboline-3-carboxylates as potent inhibitors of brain benzodiazepine receptors.
1980 Standout
Indoleamine neurons and their processes in the normal rat brain and in chronic diet‐induced thiamine deficiency demonstrated by uptake of 3H‐Serotonin
1977
Effects of a new type of 5-HT receptor agonist on male rat sexual behavior
1981 StandoutNobel
MODE AND MECHANISM OF ACTION OF NEUROTOXIC INDOLEAMINES: A REVIEW AND A PROGRESS REPORT
1978
Nervous system distribution of the serotonin 5-HT3 receptor mRNA.
1993 StandoutNobel
Effect of Nitrous Oxide on Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures
1998
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
A Gene Conferring Susceptibility to Type 2 Diabetes in Conjunction With Obesity Is Located on Chromosome 18p11
2001
Dopamine autoreceptors and the effects of drugs on locomotion and dopamine synthesis
1985 StandoutNobel
Interaction of Convulsive Ligands with Benzodiazepine Receptors
1982 StandoutScience
Drug Discovery: A Historical Perspective
2000 StandoutScience
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
1988 Standout
Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain
1977
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
Left-handedness: association with immune disease, migraine, and developmental learning disorder.
1982 Standout
Lisuride and LSD: Dopaminergic and serotonergic interactions in the ?serotonin syndrome?
1979
Multiple receptors for dopamine
1979 StandoutNature
Chronic caffeine consumption increases the number of brain adenosine receptors
1983
Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor
1986 StandoutScience
Putative endogenous ligands for the benzodiazepine receptor
1979
Receptors for the Age of Anxiety: Pharmacology of the Benzodiazepines
1980 Science
Fatal Familial Insomnia and Dysautonomia with Selective Degeneration of Thalamic Nuclei
1986
The dopamine receptor: Differential binding of d-LSD and related agents to agonist and antagonist states
1975
8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity
1982 StandoutNobel
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission—I
1985
The effects of FG 7142 and RO 15-1788 on the release of punished responding produced by chlordiazepoxide and ethanol in the rat
1986
Up-regulation of brain [3H]diazepam binding sites in chronic caffeine-treated rats
1984
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Turning in circles: The neuropharmacology of rotation
1976
Structural correlation between apomorphine and LSD: Involvement of dopamine as well as serotonin in the actions of hallucinogens
1976
Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs
1976 StandoutScience
Localization of Serotonin-Like Immunoreactivity in the Central Nervous System and Pituitary of the Rat, with Special References to the Innervation of the Hypothalamus
1981
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
Serotonin receptor knockouts: A moody subject
1998 StandoutNobel
Up-regulation of brain [3H]diazepam binding sites in chronic caffeine treated rats
1986
Increased Anxiogenic Effects of Caffeine in Panic Disorders
1985
An opioid benzodiazepine
1982 Nature
5-HT nerve terminals in the fourth ventricle of the rat brain: Their identification and distribution studied by fluorescence histochemistry and electron microscopy
1975
Effect of chronic exposure to methylxanthines on diazepam cerebral binding in female rats and their offsprings
1986
The pharmacology of iprindole, a new antidepressant
1969
Inherited prion diseases.
1994 StandoutNobel
Endogenous ligands for benzodiazepine recognition sites
1985
Methylxanthine discrimination in the rat: Possible benzodiazepine and adenosine mechanisms
1985
Response of central monoaminergic neurons to lisuride: Comparison with LSD
1979
A mathematical theory of visual hallucination patterns
1979 Standout
Central Benzodiazepine Receptor Distribution After Subcortical Hemorrhage Evaluated by Means of [ 123 I]Iomazenil and SPECT
1995
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists
1984
Works of L. Pieri being referenced
In vitro and in vivo evaluation of iodine-123-Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors.
1990
Tracing transmitter-specific neuronal systems in the mammalian brain: Supra-ependymal, serotonergic nerve fibres (T)
1974
Ro 15-4513: Partial inverse agonism at the BZR and interaction with ethanol
1988
Assignment<footref rid="foot01"><sup>1</sup></footref> of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping
1998
Disappearance of supra-ependymal 5-HT axons in the rat forebrain after electrolytic and 5,6-DHT-induced lesions of the medial forebrain bundle
1975
Lisuride- and D-LSD-induced changes of monoamine turnover in the rat brain.
1978
Decrease of dopamine and 5-hydroxytryptamine after intracerebral application of 5,6-dihydroxytryptamine
1974
Effect of Imipramine, Amitriptyline and Their Monomethyl Derivatives on Reserpine Activity
1962
LSD and dopamine receptors (reply)
1975 Nature
LSD as an agonist of dopamine receptors in the striatum
1974 Nature
Pharmacology of midazolam.
1981
Possible involvement of GABA in the central actions of benzodiazepines.
1975
A comparison of drug-induced rotation in rats lesioned in the medial forebrain bundle with 5,6-dihydroxytryptamine or 6-hydroxydopamine.
1975
Turning in MFB-lesioned rats and antagonism of neuroleptic-induced catalepsy after lisuride and LSD
1978
Mapping monoaminergic neurons with [3H]reserpine by autoradiography
1979
Nicotinamide is a brain constituent with benzodiazepine-like actions
1979 Nature
Benzodiazepine antagonist Ro 15-1788: Neurological and behavioral effects
1982
EFFECTS OF 5,6‐DIHYDROXYTRYPTAMINE AND 5,7‐DIHYDROXYTRYPTAMINE ON THE RAT CENTRAL NERVOUS SYSTEM AFTER INTRAVENTRICULAR OR INTRACEREBRAL APPLICATION AND ON BLOOD PLATELETS IN VITRO
1978
Oxidation of ceruloplasmin substrates by serum of different animal species
1960
Effects of lisuride and LSD on cerebral monoamine systems and hallucinosis
1978 Nature
Selective antagonists of benzodiazepines
1981 StandoutNature
Caffeine antagonizes several central effects of diazepam
1981