Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
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The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice
2009
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Identification of the renal erythropoietin-producing cells using transgenic mice
1993 StandoutNobel
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
1992 StandoutNature
Role of cytochrome P450 in the control of the production of erythropoietin
1990
Oxygen sensing and signaling: impact on the regulation of physiologically important genes
1999
Age-dependent expression of the erythropoietin gene in rat liver and kidneys.
1992 StandoutNobel
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Cellular sites of extrarenal and renal erythropoietin production in anaemic rats
1992
Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney.
1988
Plasma erythropoietin levels and acquired cystic disease of the kidney in patients receiving regular haemodialysis treatment
1991
Sites of erythropoietin production
1997 StandoutNobel
Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro
1993 StandoutNobel
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
2002 StandoutNobel
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Oxygen-dependent erythropoietin production by the isolated perfused rat kidney
1991
Production of Erythropoietin by Liver Cells in Vivo and in Vitro
1994 StandoutNobel
Pharmacologic Modulation of Erythropoietin Production
1988
Molecular biology of erythropoietin
1993 StandoutNobel
Lineage-Specific Hematopoietic Growth Factors
2006
Oxygen regulated gene expression: Erythropoietin as a model system
1997 StandoutNobel
Erythropoietin messenger RNA levels in developing mice and transfer of 125I-erythropoietin by the placenta.
1988
Perspectives on Oxygen Sensing
1999 StandoutNobel
Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences
1995 StandoutNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Organ distribution of erythropoietin messenger RNA in normal and uremic rats
1991 StandoutNobel
Diphenylene Iodonium Inhibits the Induction of Erythropoietin and Other Mammalian Genes by Hypoxia
1995
Erythropoietin production in kidney tubular cells
1990
The anemia of chronic renal failure: Pathophysiology and the effects of recombinant erythropoietin
1989
A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining
1973 StandoutNature
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Tumor cells are the site of erythropoietin synthesis in human renal cancers associated with polycythemia
1990
Hypoxic Induction of the Human Erythropoietin Gene: Cooperation between the Promoter and Enhancer, Each of Which Contains Steroid Receptor Response Elements
1992
Erythropoietin structure-function relationships. Mutant proteins that test a model of tertiary structure
1993
Localization of cells producing erythropoietin in murine liver by in situ hybridization [see comments]
1991
EFFECT OF HUMAN ERYTHROPOIETIN DERIVED FROM RECOMBINANT DNA ON THE ANAEMIA OF PATIENTS MAINTAINED BY CHRONIC HAEMODIALYSIS
1986 Standout
Erythropoietin production by the fetal liver in an adult environment
1987
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Regulatory elements of the erythropoietin gene
1991
A radioimmunoassay for erythropoietin
1979
Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å
1996 Science
Renal erythropoietin: Properties and production
2006
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Murine Erythropoietin Gene: Cloning, Expression, and Human Gene Homology
1986
Impact of host cell line choice on glycan profile
2017
Hepatic Regeneration and Erythropoietin Production in the Rat
1977 Science
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Erythropoietin Radioimmunoassay in Evaluating Patients with Polycythemia
1981
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
The Liver as a Source of Extrarenal Erythropoietin Production
1972
AN ANALYSIS OF HYPOPLASTIC ANÆMIA WITH SPECIAL REFERENCE TO THE USE OF OXYMETHOLONE (”ADROYD“) IN ITS THERAPY
1968
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells
1993
Human Hematopoietic Progenitors Express Erythropoietin
1998
Erythropoietin synthesis by tumor cells in a case of meningioma associated with erythrocytosis
1993
Murine erythropoietin gene: cloning, expression, and human gene homology.
1986
Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.
1991
Prehistoric exchange and interaction in southeastern southern africa: Marine shells and ostrich eggshell
1996
Production sequences of ostrich eggshell beads and settlement dynamics in the Geelbek Dunes of the Western Cape, South Africa
2005
Polycythemia: Mechanisms and Management
1981
Regulation of Erythropoietin Production: New Insights Into Molecular Mechanisms of Oxygen Homeostasis
1994 StandoutNobel
The Clonal Evolution of Tumor Cell Populations
1976 StandoutScience
APLASTIC ANEMIA: AN ANALYSIS OF 50 CASES
1958
Stimulation of erythropoietin gene transcription during hypoxia and cobalt exposure
1989
Nonrandom chromosomal abnormalities in hematologic disorders of man.
1975
Anemia induces accumulation of erythropoietin mRNA in the kidney and liver.
1986
Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration
1989
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
1993 StandoutNobel
Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein
1988 Science
Effect of angiotensin infusion on extrarenal erythropoietin production.
1982
Factors Stimulating Erythropoiesis in Frogs
1963
Rearrangement and Expression of Erythropoietin Genes in Transformed Mouse Cells
1987
The regulated expression of erythropoietin by two human hepatoma cell lines.
1987
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
1994
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
Early evidence of San material culture represented by organic artifacts from Border Cave, South Africa
2012 Standout
Effect of protein deprivation on extrarenal erythropoietin production
1978
Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.
1991 StandoutNobel
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
ASSOCIATION OF ANDROGENIC-ANABOLIC STEROID THERAPY WITH DEVELOPMENT OF HEPATOCELLULAR CARCINOMA
1972 StandoutNobel
Studies on Erythropoietic Action of Angiotensin II
1967
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Subsets of Patients with Aplastic Anemia Identified by Flow Microfluorometry
1985 StandoutNobel
Erythropoietin Production in the Anephric Rat. I. Relationship Between Nephrectomy, Time of Hypoxic Exposure, and Erythropoietin Production
1972
The kidney and erythropoiesis
1968
Hematopoietic cytokines
2008
Increased erythropoietin production in anephric rats with hyperplasia of the reticuloendothelial system induced by colloidal carbon or zymosan
1976
Factors Controlling Erythropoiesis in Birds
1966
Erythropoietin
1991 Standout
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Erythropoietin Production by Fetal Mouse Liver Cells in Response to Hypoxia and Adenylate Cyclase Stimulation*
1986
Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization
1988
HIF-2α regulates murine hematopoietic development in an erythropoietin-dependent manner
2004
Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene.
1993 StandoutNobel
Enhancer element at the 3'-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene
1991
Separation of the erythropoietin-responsive progenitors BFU-E and CFU-E in mouse bone marrow by unit gravity sedimentation
1976
Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements.
1992
Renal and Extrarenal Erythropoietin Production in Anaemic Rats
1980
Expression of the Erythropoietin Gene
1986
Brief Report: Presence of Erythropoietin in the Plasma of One Anephric Patient
1968
Studies on the Liver to Kidney Switch of Erythropoietin Production
1981
A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes.
1994
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Erythropoietin production in response to anemia or hypoxia in the newborn rat
1982
Regulation of Erythropoiesis XXII. Erythropoietin Production in the Newborn Animal
1968
Evidence for the De Novo Synthesis of Erythropoietin in Hypoxic Rats
1972
Erythropoiesis in Anephric Man *
1964
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.
1991 StandoutNobel
Erythropoietin production by the liver in fetal-neonatal life
1975
Polycythemia in transgenic mice expressing the human erythropoietin gene.
1989 StandoutNobel
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1998 Standout
Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene.
1991 StandoutNobel
Differential control of the synthesis of two hemoglobin β chains in normal mice
1977
ANDROGEN ACTIONS ON ERYTHROPOIESIS*
1968
Anemia Induces Accumulation of Erythropoietin mRNA in the Kidney and Liver
1986
Later Stone Age ostrich eggshell bead manufacture in the Northern Cape, South Africa
2008
Regulation of erythropoietin production in a human hepatoblastoma cell line
1987
The anemia of chronic renal failure in sheep. Response to erythropoietin-rich plasma in vivo.
1984
Effect of inflammatory cytokines on hypoxia-induced erythropoietin production
1992
Works of L. Jacobson being referenced
Studies on Erythropoiesis
1958
Studies on erythropoiesis.
1959
Demonstration of stimulation of erythropoiesis by plasma from anemic rats using Fe59.
1955
Studies on erythropoiesis. VIII. The effect of nephrectomy on response to hypoxic anoxia.
1958
STUDIES OF ERYTHROPOIETIN: THE HORMONE REGULATING RED CELL PRODUCTION
1959
The Size Variability of Ostrich Eggshell Beads from Central Namibia and Its Relevance as a Stylistic and Temporal Marker
1987
Studies on Erythropoiesis. XI. Reticulocyte Response of Transfusion-Induced Polycythemic Mice to Anemic Plasma from Nephrectomized Mice and to Plasma from Nephrectomized Rats Exposed to Low Oxygen
1959
Panels in Therapy. IV. The Therapeutic Management of a Case Presenting Splenomegaly, Pancytopenia, and a Hypocellular Marrow
1955
Excavations at Geduld and the Appearance of Early Domestic Stock in Namibia
1995 Standout
Cation-ratio differences in rock patina on hornfels and chalcedony using thick target PIXE
1990
Studies on Erythropoiesis. Part IV. Reticulocyte Response of Hypophysectomized and Polycythemic Rodents to Erythropoietin
1957
Chromosome Studies in Preleukemia
1966
Role of the Kidney in Erythropoiesis
1957 Nature
Time and Place: Some Observations on Spatial and Temporal Patterning in the Later Stone Age Sequence in Southern Africa [with Comments and Reply]
1980
Mechanism of the Erythropoietic Effect of Cobalt
1957 Science
Studies on Erythropoiesis. XII. The Effect of Transfusion-Induced Polycythemia in the Mother on the Fetus
1959
Studies on Erythropoiesis
1959
Studies on Erythropoiesis. III. Factors Controlling Erythropoietin Production
1957
More on Ostrich Eggshell Bead Size Variability: The Geduld Early Herder Assemblage
1987
THE PHYSIOLOGIC AND CLINICAL SIGNIFICANCE OF ERYTHROPOIETIN
1958