Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
1997 Standout
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Conversion of the substrate specificity of mouse proteinase granzyme B
1994
Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
1999
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
The Ameliorating Effect of Lumbar Puncture in Viral Meningitis
1989
Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNA
1997
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Why ion pair reversal by protein engineering is unlikely to succeed
1988 StandoutNatureNobel
Binding of the opiate-like pentapeptide methionine-enkephalin to a particulate fraction from rat brain
1976
Increased Production of Apolipoprotein B-containing Lipoproteins in the Absence of Hyperlipidemia in Transgenic Mice Expressing Cholesterol 7α-Hydroxylase
2001
Bile Acid Induction of Cytokine Expression by Macrophages Correlates with Repression of Hepatic Cholesterol 7α-Hydroxylase
2000
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
2002
Regulation of cholesterol 7α-hydroxylase gene ( CYP7A1 ) transcription by the liver orphan receptor (LXRα)
2001
Regulation of bile acid synthesis
1998
beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.
1976 StandoutNobel
Isolation and structure identification of a morphine-like peptide “enkephalin” in bovine brain
1976
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
1983 StandoutNature
Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
2010 StandoutNobel
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
A new paradigm for electrostatic catalysis of radical reactions in vitamin B 12 enzymes
2007 StandoutNobel
Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification.
1994
The opiomelanotropinergic neuronal and endocrine systems
1982
Serine Protease Mechanism and Specificity
2002
β-endorphin induced akinesia in rats: Effect of apomorphine and α-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia
1977
Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.
1976 StandoutNobel
Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness
1976 StandoutScienceNobel
Oxysterols: Modulators of Cholesterol Metabolism and Other Processes
2000
Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.
1976
Human β-endorphin: Development of tolerance and behavioral activity in rats
1977
Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin
1987
Potent prolactin and growth hormone releasing activity of more analogues of Met-enkephalin
1977 StandoutNatureNobel
β-Endorphin: Endogenous Opiate or Neuroleptic?
1977 StandoutScienceNobel
Stress-produced analgesia and morphine-produced analgesia: Lack of cross-tolerance
1978
Identification of two related pentapeptides from the brain with potent opiate agonist activity
1975 StandoutNature
Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary.
1977 StandoutNobel
Foot-shock induced stress increases β-endorphin levels in blood but not brain
1977 StandoutNatureNobel
The Preparation and Properties of Crystalline Yeast Aldolase
1962 StandoutNobel
Mechanism of the Aldolase Reaction
1965 StandoutNobel
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
Stress-induced analgesia: Neural and hormonal determinants
1980
Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary
1974
Crystal structure of leucine-enkephalin
1983 StandoutNatureNobel
Purification and sequencing of neuropeptides contained in neuron R15 of Aplysia californica.
1989 StandoutNobel
Catalytic Mechanism and Performance of Computationally Designed Enzymes for Kemp Elimination
2008 StandoutNobel
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Analgesia induced by cold-water stress: Attenuation following hypophysectomy
1979
β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland
1977 StandoutScienceNobel
Isolation, primary structure, and synthesis of α-endorphin and γ-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity
1976 StandoutNobel
Affinity purification of synthetic peptides.
1976 StandoutNobel
Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis
1979 StandoutNobel
An Analog of Enkephalin Having Prolonged Opiate-Like Effects in Vivo
1977 StandoutScienceNobel
Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.
1976
Opioid activity of synthetic and naturally occurring enkephalin peptides
1979 StandoutNobel
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Dose-dependent reductions by naloxone of analgesia induced by cold-water stress
1978
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Synthetic position 5 analogs of adrenocorticotropin fragments and their in vitro lipolytic activity
1975 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Genes Expressed in Human Tumor Endothelium
2000 StandoutScience
Pituitary Peptide
1973
Converting Trypsin to Chymotrypsin: The Role of Surface Loops
1992 Science
Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla
1978
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Opioid and Nonopioid Mechanisms of Stress Analgesia
1980 StandoutScience
Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.
1977 StandoutNobel
Endogenous opioid peptides: multiple agonists and receptors
1977 StandoutNature
Preparation and Properties of Yeast Aldolase
1961
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.
1990 StandoutNobel
Subtiligase: a tool for semisynthesis of proteins.
1994
Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase
2010 StandoutNobel
Synthesis of a Pentekontapeptide with High Lipolytic Activity Corresponding to the Carboxyl-Terminal Fifty Amino Acids of Ovine β-Lipotropin
1974
Works of L. Gráf being referenced
Lipotropic hormone obtained from human pituitary gland
1968
Comparative study on analgesic effect of Met5-enkephalin and related lipotropin fragments
1976 Nature
Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice
1993
Studies on the primary structure of human β‐lipotropic hormone
1972
Amino acid sequence of porcine β-lipotropic hormone
1971
Isolation of γ-lipotropic hormone from porcine pituitary glands
1969
DEMONSTRATION OF AN IRON-ACTIVATED ALDOLASE IN SONIC EXTRACTS OF BRUCELLA SUIS
1955
Electrostatic complementarity within the substrate-binding pocket of trypsin.
1988
Human somatotropin: covalent reconstitution of two polypeptide contiguous fragments with thrombin.
1981