Standout Papers
- Murine Ia and human DR antigens: homology of amino-terminal sequences. (1978)
- Partial amino acid sequence of HLA-A9 antigen purified with a specific xenoantiserum. (1978)
Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells
2001 StandoutScienceNobel
Recruitment of CREB-binding protein by PU.1, IFN-regulatory factor-1, and the IFN consensus sequence-binding protein is necessary for IFN-gamma-induced p67phox and gp91phox expression.
1999
The structure of an antigenic determinant in a protein
1984
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
1991 Nature
Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation
1990
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
1994
Antiinflammatory effects of nadph oxidase inhibitors
1995
The superoxide-generating NADPH oxidase: structural aspects and activation mechanism
2002
The p67 Activation Domain Regulates Electron Flow from NADPH to Flavin in Flavocytochromeb 558
1999
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
PU.1 Is Essential for p47 Promoter Activity in Myeloid Cells
1997
Oxidative stress and cardiovascular risk: the role of vascular NAD(P)H oxidase and its genetic variants
2005
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
1994 StandoutNobel
Regulators and Effectors of ras Proteins
1991
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Cytochrome b558 (p22phox) in the guinea-pig adrenal medulla
1999
Properties of a monoclonal antibody directed to the calmodulin-binding domain of rabbit skeletal muscle myosin light chain kinase
1987 StandoutNobel
Structural insights into the function of the Rab GDI superfamily
1996
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes.
1990
Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding
1988
Interactions between the Cytosolic Components p47 and p67 of the Human Neutrophil NADPH Oxidase That Are Not Required for Activation in the Cell-free System
1995
Processing and Maturation of Flavocytochromeb 558 Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly
2000
NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain
2004
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.
1990
The C-terminal Domain Revealed in the Structure of RNA Polymerase II
1996 StandoutNobel
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
1993 StandoutNobel
Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides
1994
Cracking the carbohydrate code for selectin recognition
1995 StandoutNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
Membrane Fusion
2003 StandoutNobel
Relationship of the C242Tp22phox gene polymorphism to angiographic coronary artery disease and endothelial function
1999
Human Placental NAD(P)H Oxidase: Solubilization and Properties
2001
The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems
2004
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Genetic, Biochemical, and Clinical Features of Chronic Granulomatous Disease
2000
Superoxide generation in transformed B-lymphocytes from patients with severe, malignant osteopetrosis
1999
The Dihydroxyacetone Unit—A Versatile C3Building Block in Organic Synthesis
2005
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Assembly and Activation of the Phagocyte NADPH Oxidase
1996
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
The Cdt1 protein is required to license DNA for replication in fission yeast
2000 StandoutNatureNobel
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension
2006
Mapping of Functional Domains in the p22 Subunit of Flavocytochrome b 559 Participating in the Assembly of the NADPH Oxidase Complex by “Peptide Walking”
2002
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III
2007
Assembly of the phagocyte NADPH oxidase
2004
Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells.
1992
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
SH3 — an abundant protein domain in search of a function
1992
Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.
1991
Regulation of transcription and cell identity by POU domain proteins
1991 StandoutNobel
Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.
1990
A Domain of p47phox That Interacts with Human Neutrophil Flavocytochrome b558
1995
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1
1991
Homologs of gp91 phox : cloning and tissue expression of Nox3, Nox4, and Nox5
2001
Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase
2004
Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
1999 StandoutNobel
Expression of Cytochrome bsss on B Cell- and CD 30 Positive-lymphomas
1993
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Infection in Organ-Transplant Recipients
1998 Standout
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
Molecular Characterization of a Superoxide-Generating NAD(P)H Oxidase in the Ventilatory Muscles
2002
NADPH Oxidase-Mediated Oxidative Stress: Genetic Studies of the p22 phox Gene in Hypertension
2005
Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.
1992 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Chemical, Enzymatic and Structural Studies in Molecular Glycobiology
1997
HLA‐DC antigens can serve as recognition elements for human cytotoxic T lymphocytes
1984
Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox.
1996
Correlation between segmental mobility and the location of antigenic determinants in proteins
1984 Nature
Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes
1983 Nature
Structural Basis for Antigen-Antibody Recognition
1986 StandoutScienceNobel
Chronic granulomatous disease
2000
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Design and synthesis of cyclic sialyl Lewis X mimetics: a remarkable enhancement of inhibition by pre-organizing all essential functional groups
2000
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Angiotensin II Induces p67 phox mRNA Expression and NADPH Oxidase Superoxide Generation in Rabbit Aortic Adventitial Fibroblasts
1998
cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.
1996
A Variant of p22 phox , Involved in Generation of Reactive Oxygen Species in the Vessel Wall, Is Associated With Progression of Coronary Atherosclerosis
2000
Chemical Glycobiology
2001 StandoutScienceNobel
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
Restoration of superoxide generation to a chronic granulomatous disease- derived B-cell line by retrovirus mediated gene transfer
1992
Cell type-specific enhancer element associated with a mouse MHC gene, Eβ
1984 StandoutNatureNobel
Molecular Characterization and Localization of the NAD(P)H Oxidase Components gp91- phox and p22- phox in Endothelial Cells
2000
Karyopherin β2 mediates nuclear import of a mRNA binding protein
1997 StandoutNobel
Synthesis of Sugar Arrays in Microtiter Plate
2002
Characterization of the 47-Kilodalton Autosomal Chronic Granulomatous Disease Protein: Tissue-Specific Expression and Transcriptional Control by Retinoic Acid
1990
Polymorphism of the NADH/NADPH Oxidase p22 phox Gene in Patients With Coronary Artery Disease
1998
O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA.
1992
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
The Atomic Mobility Component of Protein Antigenicity
1985
Synthetic Cyclic Oligosaccharides
1998 StandoutNobel
Relationship between phosphorylation and translocation to the plasma membrane of p47phox and p67phox and activation of the NADPH oxidase in normal and Ca2+-depleted human neutrophils
1993
Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum
1993 StandoutScienceNobel
Recruitment of CREB-Binding Protein by PU.1, IFN-Regulatory Factor-1, and the IFN Consensus Sequence-Binding Protein Is Necessary for IFN-γ-Induced p67phoxand gp91phoxExpression
1999
A nuclear localization domain in the hnRNP A1 protein.
1995
156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox.
1994
The Arachidonate-activable, NADPH Oxidase-associated H+ Channel
1995
Functional expression of a microinjected Edα gene in C57BL/6 transgenic mice
1985 StandoutNatureNobel
Conserved Structures of Mediator and RNA Polymerase II Holoenzyme
1999 StandoutScienceNobel
UGO1 Encodes an Outer Membrane Protein Required for Mitochondrial Fusion
2001
The Cellular Functions of Small GTP-Binding Proteins
1990 Science
Targeting of transgene expression to monocyte/macrophages by the gp91-phox promoter and consequent histiocytic malignancies.
1991
Analysis of glycosylation sites on gp91phox, the flavocytochrome of the NADPH oxidase, by site-directed mutagenesis and translation in vitro
1997
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis.
1992
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein
1984 Nature
Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules
1981
Detection of gp91-phox precursor protein in B-cell lines from patients with X-linked chronic granulomatous disease as an indicator for mutations impairing cytochrome b558 biosynthesis
1996
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.
1988
Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma.
1988
An NAD(P)H oxidase regulates growth and transcription in melanoma cells
2002
Analysis of HLA-D region-associated molecules with monoclonal antibody.
1979
Absolute requirement for GTP in activation of human neutrophil NADPH oxidase in a cell-free system: role of ATP in regenerating GTP.
1992
Inhibition of mucin glycosylation by aryl-N-acetyl-α-galactosaminides in human colon cancer cells
1989
Two Forms of Autosomal Chronic Granulomatous Disease Lack Distinct Neutrophil Cytosol Factors
1988 Science
Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2
1991 Science
Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).
1992
Phagocyte NADPH oxidase: a multicomponent enzyme essential for host defenses.
2005
Glycals in Organic Synthesis: The Evolution of Comprehensive Strategies for the Assembly of Oligosaccharides and Glycoconjugates of Biological Consequence
1996
Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.
1985 StandoutNobel
High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays
2004
Isolation of monoclonal antibodies specific for products of avian oncogene myb.
1984 StandoutNobel
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.
1994
Upregulation of p67phoxand gp91phoxin aortas from angiotensin II-infused mice
2000
Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid.
1990
Selectin−Carbohydrate Interactions: From Natural Ligands to Designed Mimics
1998
Partial deficiency of erythrocyte spectrin in hereditary spherocytosis
1985 StandoutNatureNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes
1992
A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication.
1996 StandoutNobel
Use of immunoglobulin-loaded protein A-bearing staphylococci as a primary solid phase immunoadsorbent in radioimmunoassay.
1980
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Synthesis of Complex Carbohydrates and Glycoconjugates: Enzyme-Based and Programmable One-Pot Strategies
2000
Asymmetric Enamine Catalysis
2007 StandoutNobel
The respiratory burst oxidase of human neutrophils. Guanine nucleotides and arachidonate regulate the assembly of a multicomponent complex in a semirecombinant cell-free system.
1993
PU.1 as an essential activator for the expression of gp91phoxgene in human peripheral neutrophils, monocytes, and B lymphocytes
1998
Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes
1986 StandoutNatureNobel
A molecular map of the immune response region from the major histocompatibility complex of the mouse
1982 Nature
The p47phox mouse knock-out model of chronic granulomatous disease.
1995
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.
1993
Isolation of Monoclonal Antibodies Specific for Products of Avian Oncogene myb
1984 StandoutNobel
The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region
1983 Nature
Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60 c-src
1990 Science
Works of L E Walker being referenced
Association of a Ras-related protein with cytochrome b of human neutrophils
1989 Nature
Structure-Activity Relationships of Sialyl Lewis x-Containing Oligosaccharides. 1. Effect of Modifications of the Fucose Moiety
1994
Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans.
1984
Characterization of the specificity of peptide binding to four DR haplotypes.
1990
Structural studies of murine I-E and human DR antigens
1979
Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.
1983
Partial amino acid sequence of HLA-A9 antigen purified with a specific xenoantiserum.
1978 StandoutNobel
Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent.
1980
Sequence homology and immunologic cross-reactivity of human cytomegalovirus with HLA-DR beta chain: a means for graft rejection and immunosuppression
1988
Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.
1988
Chemical-enzymic synthesis and conformational analysis of sialyl Lewis X and derivatives
1992
Murine Ia and human DR antigens: homology of amino-terminal sequences.
1978 StandoutNobel
Antibody-coated protein a-bearing Staphylococcus aureus: A versatile and stable immune reagent
1979