Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
New tools for integrated genetic and physical analyses of the Escherichia coli chromosome
1995
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
2007
Decreased Neonatal Dietary Fat Absorption and T Cell Cytotoxicity in Pancreatic Lipase-related Protein 2-Deficient Mice
1998
Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus.
1992
Rapid evolution of the DNA-binding site in LAGLIDADG homing endonucleases
2001
Coevolution of a Homing Endonuclease and Its Host Target Sequence
2007
Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis.
1989 StandoutNobel
Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks
2009
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
1998
Chromatin structural elements and chromosomal translocations in leukemia
2006
Chromosomal Double-Strand Breaks Introduced in Mammalian Cells by Expression of I-Sce I Endonuclease
2003
Infectious introns
1989
Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
2003
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.
1993
Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene
1991 StandoutNature
Repair of Strand Breaks by Homologous Recombination
2013
Homing endonuclease structure and function
2005
Molecular genetics of group I introns: RNA structures and protein factors required for splicing — a review
1988
Meganucleases and DNA Double-Strand Break-Induced Recombination: Perspectives for Gene Therapy
2007
Restriction enzymes and their isoschizomers
1990 StandoutNobel
Reverse self-splicing of the tetrahymena group I intron: Implication for the directionality of splicing and for intron transposition
1989 StandoutNobel
Directed evolution of homing endonuclease I-SceI with altered sequence specificity
2009
Isolation and Characterization of New Homing Endonuclease Specificities at Individual Target Site Positions
2004
Diagnosis of Sickle Cell Anemia and β-Thalassemia with Enzymatically Amplified DNA and Nonradioactive Allele-Specific Oligonucleotide Probes
1988
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
The fission yeast gene pmt1+encodes a DNA methyltransferase homologue
1995 StandoutNobel
Markerless gene replacement in Escherichia coli stimulated by a double-strand break in the chromosome
1999
I- Ppo I and I- Cre I homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment 1 1Edited by G. Smith
1998
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA
1992 Standout
Homing endonuclease genes: the rise and fall and rise again of a selfish element
2004
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae
1992 Nature
Efficient in toto targeted recombination in mouse liver by meganuclease‐induced double‐strand break
2006
CRISPR–Cas systems exploit viral DNA injection to establish and maintain adaptive immunity
2017 Nature
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
1999 Standout
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Chromosome Breaks and Genomic Instability
2000
The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
1988 Nature
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs
2010 StandoutNobel
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
1991 StandoutNature
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
The spectrin-actin junction of erythrocyte membrane skeletons
1989
Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation
2008
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.
1994
Three class I introns in the ND4L/ND5 transcriptional unit of Neurospora crassa mitochondria
1987
Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes
1989 Science
Delayed de novo methylation in teratocarcinoma suggests additional tissue-specific mechanisms for controlling gene expression
1983 Nature
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
1990 Standout
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.
1994
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Introduction of Double-Strand Breaks into the Genome of Mouse Cells by Expression of a Rare-Cutting Endonuclease
1994
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation
1994
Interfacial Catalysis: the Mechanism of Phospholipase A 2
1990 StandoutScience
Extensive Nuclear DNA Sequence Diversity Among Chimpanzees
1999 StandoutScienceNobel
Mobile RNA catalysts
1988 Nature
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease
2009
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors
1998 StandoutScience
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
1995 StandoutNature
Both CRISPR /C as‐based nucleases and nickases can be used efficiently for genome engineering in A rabidopsis thaliana
2014
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
2000 Standout
Crystallization of ribozymes and small RNA motifs by a sparse matrix approach.
1993 StandoutNobel
Deletion of the c-kit protooncogene in the human developmental defect piebald trait.
1991
Purification of a site-specific endonuclease, I-Sce II, encoded by intron 4 alpha of the mitochondrial coxI gene of Saccharomyces cerevisiae.
1990
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Genetic differences accounting for evolution and pathogenicity of simian immunodeficiency virus from a sooty mangabey monkey after cross-species transmission to a pig-tailed macaque
1992 StandoutNobel
Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions.
1993
Reiterative Recombination for the in vivo assembly of libraries of multigene pathways
2011
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Growth Factors and Cancer
1991 StandoutScience
Detection of DNA sequence polymorphisms by enzymatic amplification and direct genomic sequencing.
1989
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Autoproteolysis in nucleoporin biogenesis
1999 StandoutNobel
Directed Evolution and Substrate Specificity Profile of Homing Endonuclease I-SceI
2006
The Complete Genome Sequence of Escherichia coli K-12
1997 StandoutScience
Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena.
1987 StandoutNobel
De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.
1982
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins.
1991 StandoutNobel
Gene Targeting by Homologous Recombination in Drosophila
2000 Science
More of the catalytic triad
1990 Nature
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Bacterial Origin of a Chloroplast Intron: Conserved Self-Splicing Group I Introns in Cyanobacteria
1990 Science
Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
1991
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells.
1994
I-SceI Endonuclease, a New Tool for Studying DNA Double-Strand Break Repair Mechanisms in Drosophila
1999
Erythrocyte P Antigen: Cellular Receptor for B19 Parvovirus
1993 StandoutScience
Band 3 and ankyrin homologues are present in eye lens: Evidence for all major erythrocyte membrane components in same non-erythroid cell
1987
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice
2002 StandoutNobel
Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions.
1991
Works of L d'Auriol being referenced
Expression of the Human Parvovirus B19 Protein Fused to Protein A in Escherichia coli: Recognition By IgM and IgG Antibodies in Human Sera
1989
Structural alterations of the BCR and ABL genes in Phl positive acute leukemias with rearrangements in the BCR gene first intron: further evidence implicating Alu sequences in the chromosome translocation
1989
Localization of the human c-kit protooncogene on the q11?q12 region of chromosome 4
1988
Substitution of leucine for isoleucine in a sequence highly conserved among retroviral envelope surface glycoproteins attenuates the lytic effect of the Friend murine leukemia virus.
1991
Determination of the spectrum of beta-thalassemia genes in Spain by use of dot-blot analysis of amplified beta-globin DNA.
1988
c-kit mRNA expression in human and murine hematopoietic cell lines.
1989
Recognition and cleavage site of the intron-encoded omega transposase.
1988
Organization of the human lipoprotein lipase gene and evolution of the lipase gene family.
1989
Studies on the Restriction of Ecotropic Murine Retrovirus Replication in Mouse Teratocarcinoma Cells
1981
Universal code equivalent of a yeast mitochondrial intron reading frame is expressed into E. coli as a specific double strand endonuclease
1986
Sp alpha I/78: a mutation of the alpha I spectrin domain in a white kindred with HE and HPP phenotypes
1989
Isolation of cDNA clones and complete amino acid sequence of human erythrocyte glycophorin C.
1986