L. Bardou

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Metabolism of Arachidonic Acid to 20-Hydroxy-5,8,11,14-eicosatetraenoic Acid by P450 Enzymes in Human Liver: Involvement of CYP4F2 and CYP4A11

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol

Interindividual Variability of the Clinical Pharmacokinetics of Methadone

Predicting plasma protein binding of drugs: a new approach

Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1

Structural Basis of the Drug-binding Specificity of Human Serum Albumin

Ritonavir

Head and neck cancer

Diversification of Catalytic Function in a Synthetic Family of Chimeric Cytochrome P450s

Libraries of hybrid proteins from distantly related sequences

Catalytic Assays for Human Cytochrome P450

Association of cytochrome P450 induction with oxidative stressin vivoas evidenced by 3-hydroxylation of salicylate

Contaminant-stimulated Reactive Oxygen Species Production and Oxidative Damage in Aquatic Organisms

Cancer-associated cachexia

Measuring reactive species and oxidative damagein vivoand in cell culture: how should you do it and what do the results mean?

IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans

The Endocannabinoid System as an Emerging Target of Pharmacotherapy

A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Genetic susceptibility–molecular epidemiology of head and neck cancer

Classification of carcinogenic chemicals in the work area by the German MAK Commission11Members and coworkers of the German MAK Commission who contributed to the establishment of the new classification scheme and the evaluation of the substances are: Ulrich Andrae (Neuherberg); Britta Brinkmann (Weihenstephan); Johannes G. Filser (Neuherberg); Stephan Forderkunz (Weihenstephan); Hans-Peter Gelbke (Ludwigshafen); Hermann Kappus (Berlin); Hans-Günter Neumann (Würzburg); Klaus H. Norpoth (Essen); Heinz Walter Thielmann (Heidelberg); Riccarda Thier (Dortmund).: current examples for the new categories

Renal Toxicity and Carcinogenicity of Trichloroethylene: Key Results, Mechanisms, and Controversies

Genetic Polymorphism in CYP2E1: Population Distribution of CYP2E1 Activity

Effect of Tenofovir Disoproxil Fumarate on the Pharmacokinetics and Pharmacodynamics of Total, R‐, and S‐Methadone

Epidemiology, Staging, and Screening of Head and Neck Cancer

Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain

Fluorescence probes used for detection of reactive oxygen species

Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies

Cisplatin in cancer therapy: Molecular mechanisms of action

Imaginary Relish and Exquisite Torture: The Elaborated Intrusion Theory of Desire.

Herb-Drug Interactions

Robustness of chlorzoxazone as an in vivo measure of cytochrome P450 2E1 activity

Other Drugs Acting on Nervous System Associated with QT-Interval Prolongation

Cytochrome P450 ω-Hydroxylase Pathway of Tocopherol Catabolism

Oxidative stress and neurodegeneration: where are we now?

Prevention of head and neck cancer: Current status and future prospects

Formation of 20-Hydroxyeicosatetraenoic Acid, a Vasoactive and Natriuretic Eicosanoid, in Human Kidney

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Alcohol and Marijuana: Effects on Epilepsy and Use by Patients with Epilepsy

IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans

Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial

Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?

What makes a good case–control study?

Carcinogenicity categorization of chemicals—new aspects to be considered in a European perspective

Acrylamide and 5-hydroxymethylfurfural (HMF): A review on metabolism, toxicity, occurrence in food and mitigation strategies

Identification of acrylate, the product of the dehydration of (R)‐lactate catalysed by cell‐free extracts from Clostridium propionicum

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

Drinking Water Disinfection Byproducts (DBPs) and Human Health Effects: Multidisciplinary Challenges and Opportunities

Chemical Routes for the Transformation of Biomass into Chemicals

Quantitative gas chromatographic determination of perfluorooctanoic acid as the benzyl ester in plasma and urine

Reactive Species and Antioxidants. Redox Biology Is a Fundamental Theme of Aerobic Life

In vivoRole of CytochromeP450 2E1 and Glutathione-S-Transferase Activity for Acrylamide Toxicokinetics in Humans

Expression of Glutathione-Dependent Enzymes and Cytochrome P450s in Freshly Isolated and Primary Cultures of Proximal Tubular Cells from Human Kidney

Compound-Specific, Quantitative Characterization of Organic Fluorochemicals in Biological Matrices

Prognostic Factors in Advanced Cancer Patients: Evidence-Based Clinical Recommendations—A Study by the Steering Committee of the European Association for Palliative Care

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

SEX‐HORMONE‐BINDING GLOBULIN

Hormone metabolism and action: Testosterone and metabolites in prostate organ culture

Development and application of a human PBPK model for bromodichloromethane to investigate the impacts of multi‐route exposure

Interaction of methadone with substrates of human hepatic cytochrome P450 3A4

Cytochrome P450 4A and 2E1 expression in human kidney microsomes

Determination of cytochrome P450 2E1 activity in microsomes by thin-layer chromatography using [2-14C]chlorzoxazone

Cytochromes P4502E1 and P4501A1 Genotypes and Susceptibility to Cirrhosis or Upper Aerodigestive Tract Cancer in Alcoholic Caucasians

Involvement of Cytochromes P-450 2E1 and 3A4 in the 5-Hydroxylation of Salicylate in Humans

Metabolism of radioactive 5α-androstane-3β, 17β-diol

CLINICAL INTEREST OF THE IN VIVO MEASUREMENT OF CYP2E1 IN ALCOHOLIC LIVER DISEASES

Acetaldehyde Adducts with Serum Proteins: Effect on Diazepam and Phenytoin Binding

Quantitative gas chromatographic determination of low-molecular-weight straight-chain carboxylic acids as their p-bromophenacyl esters after extractive alkylation in acidic medium