Citation Impact
Citing Papers
Antiseptics and Disinfectants: Activity, Action, and Resistance
1999 Standout
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
2017 Science
Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats
2004
An orthotopic colon cancer model for studying the B7-H3 antitumor effect in vivo
2006
Cell mechanics and the cytoskeleton
2010 StandoutNature
Targeting the E3 ubiquitin ligases DCAF15 and cereblon for cancer therapy
2020
Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820
2019
Clinical outcome in children with recurrent neuroblastoma treated with ABT‐751 and effect of ABT‐751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro
2009
Copper-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids
2013
One-pot synthesis of benzo[c]carbazoles by photochemical annulation of 2-chloroindole-3-carbaldehydes
2008
Anti-angiogenesis Effects of Borrelidin are Mediated through Distinct Pathways: Threonyl-tRNA Synthetase and Caspases are Independently Involved in Suppression of Proliferation and Induction of Apoptosis in Endothelial Cells
2003
Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase
2003
Synthesis and cytotoxic activity of the heptaphylline and 7-methoxyheptaphylline series
2011
Targeting tumor-associated carbonic anhydrase IX in cancer therapy
2006
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered
2004
Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle
1998 Standout
Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth
2006
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
2019
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride
2003
E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
2020
Iterative strategies for the synthesis of deoxypropionates
2010 StandoutNobel
Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T lymphocytes. Evaluation of p53 and Bcl-2 proteins in the apoptotic mechanism
2009
Sideromycins: tools and antibiotics
2009
Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055
2004
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties
2004
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
2004 StandoutNature
Catechol‐Based Biomimetic Functional Materials
2012
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
2008 Standout
Borrelidin analogues with antimalarial activity: Design, synthesis and biological evaluation against Plasmodium falciparum parasites
2013 StandoutNobel
An Efficient and General Method for the Synthesis of α,ω‐Difunctional Reduced Polypropionates by Zr‐Catalyzed Asymmetric Carboalumination: Synthesis of the Scyphostatin Side Chain
2004 StandoutNobel
Carbonic anhydrase inhibitors
2002 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
Stereoselective Total Synthesis of (−)‐Borrelidin
2004
Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents?
2001
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Carbonic anhydrase inhibitors: The first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX
2004
Microtubules as a target for anticancer drugs
2004 Standout
Iterative Deoxypropionate Synthesis Based on a Copper‐Mediated Directed Allylic Substitution: Formal Total Synthesis of Borrelidin (C3–C11 Fragment)
2006
Evaluation of antiproliferative activities and apoptosis induction caused by copper(II)–benzothiazolesulfonamide complexes in Jurkat T lymphocytes and Caco-2 cells
2008
Borrelidin Inhibits a Cyclin-dependent Kinase (CDK), Cdc28/Cln2, of Saccharomyces cerevisiae.
2001
Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?
2004
Treatment of Acute Lymphoblastic Leukaemia
2007
Chemistry and biology of siderophores
2010 Standout
Liposomal drug delivery systems: From concept to clinical applications
2012 Standout
Selective degradation of splicing factor CAPERα by anticancer sulfonamides
2017
Small-Molecule Degraders beyond PROTACs—Challenges and Opportunities
2021
The HPV E7 oncoprotein inhibits tumor necrosis factor α-mediated apoptosis in normal human fibroblasts
2001
Synthesis and biological evaluation of aryl azide derivatives of combretastatin a-4 as molecular probes for tubulin
2000
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide
2004
Cell cycle kinases as therapeutic targets for cancer
2009
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues
2006
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Mechanisms of Action of the Novel Sulfonamide Anticancer Agent E7070 on Cell Cycle Progression in Human Non-Small Cell Lung Cancer Cells
2001
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates
2004
Palladium-catalyzed oxidative C–H bond coupling of indoles and benzaldehydes: a new approach to the synthesis of 3-benzoylindoles
2013
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Iridium(iii )-catalyzed regioselective C7-sulfonamidation of indoles
2016
Palladium-Catalyzed Reaction of o-Alkynyltrifluoroacetanilides with 1-Bromoalkynes. An Approach to 2-Substituted 3-Alkynylindoles and 2-Substituted 3-Acylindoles
2005
Total Synthesis of Borrelidin
2007 StandoutNobel
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides—a new target for the design of antitumor and antiglaucoma drugs?
2005
Stepwise and one-pot cross-coupling–heteroannulation approaches toward 2-substituted C5-, C6-, and C7-nitroindoles
2004
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis.
2002
Array-Based Structure and Gene Expression Relationship Study of Antitumor Sulfonamides IncludingN-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide andN-(3-Chloro-7-indolyl)-1,4-benzenedisulfonamide
2002
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
On the Mechanism of Cu-Catalyzed Enantioselective Extended Conjugate Additions: A Structure-Based Approach
2014 StandoutNobel
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX
2003
All-Catalytic, Efficient, and Asymmetric Synthesis of α,ω-Diheterofunctional Reduced Polypropionates via “One-Pot” Zr-Catalyzed Asymmetric Carboalumination−Pd-Catalyzed Cross-Coupling Tandem Process
2005 StandoutNobel
Active transport of siderophore-mimicking antibacterials across the outer membrane
1999
Acylation of indoles via photoredox catalysis: a route to 3-acylindoles
2015
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Chemo- and stereoselectivity in titanium-mediated regioselective ring-opening reaction of epoxides at the more substituted carbon
2005
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
A Direct Access to 7-Aminoindoles via Iridium-Catalyzed Mild C–H Amidation of N-Pivaloylindoles with Organic Azides
2016
Enantioselective Total Synthesis of Borrelidin
2003
Efficient Preparation of 2-Indolyl-1-nitroalkane Derivatives Employing Nitroalkenes as Versatile Michael Acceptors: New Practical Linear Approach to Alkyl 9H-β-Carboline-4-carboxylate
2005
Efficient purification of recombinant human tumor necrosis factor beta from Escherichia coli yields biologically active protein with a trimeric structure that binds to both tumor necrosis factor receptors
1991
Carbonic Anhydrase Inhibitors: The First Selective, Membrane‐Impermeant Inhibitors Targeting the Tumor‐Associated Isozyme IX.
2004
A Randomized Phase II Pharmacokinetic and Pharmacodynamic Study of Indisulam as Second-Line Therapy in Patients with Advanced Non–Small Cell Lung Cancer
2007
A Facile Access to Primary Alkylamines and Anilines via Ir(III)-Catalyzed C–H Amidation Using Azidoformates
2016
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
2014 Standout
Mild and Selective Ru-Catalyzed Formylation and Fe-Catalyzed Acylation of Free (N–H) Indoles Using Anilines as the Carbonyl Source
2011
Induction of apoptosis in K562 cells by jolkinolide B
2006
Synthetic Studies on Borrelidin: Enantioselective Synthesis of the C1−C12 Fragment
2003
Species selectivity of new siderophore-drug conjugates that use specific iron uptake for entry into bacteria
1996
Iron Metabolism in Pathogenic Bacteria
2000
Application of Conformation Design in Acyclic Stereoselection: Total Synthesis of Borrelidin as the Crystalline Benzene Solvate
2003
Total Synthesis of (−)-Borrelidin
2004
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
Total synthesis of borrelidin
2005 StandoutNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Sulfur Dioxide Mediated One-Pot, Three- and Four-Component Syntheses of Polyfunctional Sulfonamides and Sulfonic Esters: Study of the Stereoselectivity of the Ene Reaction of Sulfur Dioxide
2004
ELECTROPHILIC SUBSTITUTION OF INDOLES CATALYZED BY TRIPHENYL PHOSPHONIUM PERCHLORATE: SYNTHESIS OF 3-ACETYL INDOLES AND BIS-INDOLYLMETHANE DERIVATIVES
2002
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
The Halogen Bond
2016 Standout
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Synthesis of the marine alkaloid caulersin
2004
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Acid-catalyzed condensation of 2,2′-diamino-1,1′-biaryls for the synthesis of benzo[c]carbazoles
2011
A Synthetic E7 Gene of Human Papillomavirus Type 16 That Yields Enhanced Expression of the Protein in Mammalian Cells and Is Useful for DNA Immunization Studies
2003 StandoutNobel
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Transition-Metal-Catalyzed Addition of Heteroatom−Hydrogen Bonds to Alkynes
2004 Standout
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
InCl3 and In(OTf)3 catalyzed reactions: synthesis of 3-acetyl indoles, bis-indolylmethane and indolylquinoline derivatives
2002
Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors
2008
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Solid-Phase Synthesis of 2,3,5-Trisubstituted Indoles
2001
Microbial iron chelators as drug delivery agents: the rational design and synthesis of siderophore-drug conjugates
1993
Regiocontrolled Direct C−H Arylation of Indoles at the C4 and C5 Positions
2017
Novel sulphonamide derivatives for the treatment of cancer
2000
Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds and Evaluation of Enterobactin–Cargo Conjugate Uptake
2012
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Prevention of Drug Access to Bacterial Targets: Permeability Barriers and Active Efflux
1994 Science
Works of Kyosuke Kitoh being referenced
In vivo tumor growth inhibition produced by a novel sulfonamide, E7010, against rodent and human tumors.
1994
Mechanism of action of E7010, an orally active sulfonamide antitumor agent: inhibition of mitosis by binding to the colchicine site of tubulin.
1997
Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents
2002
A novel carbazole topoisomerase II poison, ER‐37328: potent tumoricidal activity against human solid tumors in vitro and in vivo
2003
A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors
2000
Effect of E7010 on liver metastasis and life span of syngeneic C57BL/6 mice bearing orthotopically transplanted murine Colon 38 tumor
2001
Novel sulfonamides as potential, systemically active antitumor agents
1992
E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo
2001
Rapid development of hepatic metastasis with high incidence following orthotopic transplantation of murine colon 38 carcinoma as intact tissue in syngeneic C57BL/6 mice
1999
Synthesis and Antitumor Activities of Novel 6-5 Fused Ring Heterocycle Antifolates: N-[4-[.omega.-(2-Amino-4-substituted-6,7-dihydrocyclopenta[d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic Acids
1994
Borrelidin is an Angiogenesis Inhibitor; Disruption of Angiogenic Capillary Vessels in a Rat Aorta Matrix Culture Model.
1997
A General Method for Acylation of Indoles at the 3-Position with Acyl Chlorides in the Presence of Dialkylaluminum Chloride
2000
E-0702, a new cephalosporin, is incorporated into Escherichia coli cells via the tonB-dependent iron transport system
1987
Discovery of Novel Antitumor Sulfonamides Targeting G1 Phase of the Cell Cycle
1999
Deletion of lysine 84 to lysine 89 enhances the cytotoxicity and the receptor binding affinity of human lymphotoxin.
1990
Synthesis and Evaluation of Novel Pyrimido-Acridone, -Phenoxadine, and -Carbazole as Topoisomerase II Inhibitors
2004
Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.
2002
Establishment of a quantitative mouse dorsal air sac model and its application to evaluate a new angiogenesis inhibitor.
1999
In vitro antibacterial activity of E-0702, a new semisynthetic cephalosporin
1982