Kyle Chang

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

A proteomic atlas of senescence-associated secretomes for aging biomarker development

Replicative DNA polymerase mutations in cancer

Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

The mini-driver model of polygenic cancer evolution

Cancer immunoediting and resistance to T cell-based immunotherapy

Organoid Models of Tumor Immunology

Colonoscopy-based colorectal cancer modeling in mice with CRISPR–Cas9 genome editing and organoid transplantation

The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth

Tumour heterogeneity and resistance to cancer therapies

Young-onset colorectal cancer

Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors

Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15

Hypermutation in human cancer genomes: footprints and mechanisms

The molecular genetics of colorectal cancer

Hyper-Progressive Disease: The Potential Role and Consequences of T-Regulatory Cells Foiling Anti-PD-1 Cancer Immunotherapy

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

Oncogenic Kras drives invasion and maintains metastases in colorectal cancer

MLH1‐silenced and non‐silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes

Abstract 1256: Lynch syndrome premalignancy upregulates immune checkpoints independently from neoantigen and mutational rates

Detection of Pathogenic Germline Variants Among Patients With Advanced Colorectal Cancer Undergoing Tumor Genomic Profiling for Precision Medicine