Citation Impact
Citing Papers
The biomass distribution on Earth
2018 Standout
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
2015
Macrophage metabolic reprogramming during chronic lung disease
2020
Autophagy in infection, inflammation and immunity
2013 Standout
Mouse models to study inner ear development and hereditary hearing loss
2007
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
2013
NF-κB signaling in inflammation
2017 Standout
Melioidosis
2018 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Autophagy and Cellular Immune Responses
2013
Converging roles of caspases in inflammasome activation, cell death and innate immunity
2015
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Activation and regulation of the inflammasomes
2013 Standout
Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?
2019
Rapamycin: One Drug, Many Effects
2014 Standout
Inflammasome Complexes: Emerging Mechanisms and Effector Functions
2016
Macrophages in immunoregulation and therapeutics
2023 Standout
Type I interferons in infectious disease
2015 Standout
Caspase-1-Dependent and -Independent Cell Death Pathways in Burkholderia pseudomallei Infection of Macrophages
2014
Immunogenic cell death in cancer and infectious disease
2016 Standout
Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection
2014
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
2013
The molecular machinery of regulated cell death
2019 Standout
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
Salmonellae interactions with host processes
2015
Differential roles of caspase-1 and caspase-11 in infection and inflammation
2017
Pyroptosis: mechanisms and diseases
2021 Standout
A tense situation: forcing tumour progression
2009 Standout
Inflammasomes in Intestinal Inflammation and Cancer
2011
Regulation of inflammasome signaling
2012
Noncanonical Inflammasomes: Caspase-11 Activation and Effector Mechanisms
2013
Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection
2013
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
2016
A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation
2016
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Pyroptosis: A new frontier in cancer
2019 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Revisiting Caspase-11 Function in Host Defense
2013
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
2012 Nature
Tumour-associated macrophages as treatment targets in oncology
2017 Standout
Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity
2015
Mechanisms and Functions of Inflammasomes
2014 Standout
Targeting autophagy in cancer
2017 Standout
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
Geroscience: Linking Aging to Chronic Disease
2014 Standout
Caspase crosstalk: integration of apoptotic and innate immune signalling pathways
2014
The Hallmarks of Aging
2013 Standout
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
2015 Standout
The PI3K Pathway in Human Disease
2017 Standout
Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol
2013
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
Gasdermins: Effectors of Pyroptosis
2017 Standout
mTOR is a key modulator of ageing and age-related disease
2013 Nature
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
2015 Standout
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
2015 Standout
Programmed cell death and its role in inflammation
2015
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
2018 Standout
Development of the hair bundle and mechanotransduction
2007
Neurosensory mechanotransduction
2008 StandoutNobel
The Shigella OspC3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection
2013
Control of adaptive immunity by the innate immune system
2015 Standout
An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
2013
Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens
2014
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3
2015
Dysregulation ofEscherichia coliα-hemolysin expression alters the course of acute and persistent urinary tract infection
2015
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity
2022 StandoutNobel
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Pyroptotic cell death defends against intracellular pathogens
2015
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Caspase-11 Protects Against Bacteria That Escape the Vacuole
2013 Science
Modulation of Inflammasome Pathways by Bacterial and Viral Pathogens
2011
Intracellular sensing of microbes and danger signals by the inflammasomes
2011
Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death
2015
Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia
2012
Life under extreme energy limitation: a synthesis of laboratory- and field-based investigations
2015
Guava flavonoid glycosides prevent influenza A virus infection via rescue of P53 activity
2018
Cell death: a review of the major forms of apoptosis, necrosis and autophagy
2019 Standout
Inflammasomes and Their Roles in Health and Disease
2012
Caspase-1: The inflammasome and beyond
2013
Recognition of Bacteria by Inflammasomes
2012
Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens
2015
Autophagy and Burkholderia
2014
Regulation of inflammasome activation
2015
Caspase‐8: regulating life and death
2017 Standout
Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo
2015
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Works of Kyle Caution being referenced
Depletion of the Ubiquitin-binding Adaptor Molecule SQSTM1/p62 from Macrophages Harboring cftr ΔF508 Mutation Improves the Delivery of Burkholderia cenocepacia to the Autophagic Machinery
2012
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
2015
Mutations in TRIOBP, Which Encodes a Putative Cytoskeletal-Organizing Protein, Are Associated with Nonsyndromic Recessive Deafness
2005
Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages
2011
Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization
2012
Apoptosis-associated Speck-like Protein (ASC) Controls Legionella pneumophila Infection in Human Monocytes
2010
Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis
2011
Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients
2012
Aging is associated with hypermethylation of autophagy genes in macrophages
2016
Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1β production in macrophages
2010
Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages
2016