Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Spatially resolved, highly multiplexed RNA profiling in single cells
2015 StandoutScience
Effect of Niclosamide on Basal-like Breast Cancers
2014
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Protein conducting channels—mechanisms, structures and applications
2012 StandoutNobel
Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus
2014 StandoutNobel
Intracellular Nucleic Acid Sensors and Autoimmunity
2011 StandoutNobel
Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM
2017
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
2022 Standout
Reducing cell intrinsic immunity to mRNA vaccine alters adaptive immune responses in mice
2023 StandoutNobel
Drug repositioning: a machine-learning approach through data integration
2013
Suppression of Lysosome Function Induces Autophagy via a Feedback Down-regulation of MTOR Complex 1 (MTORC1) Activity
2013
Noncompetitive binding of PpiD and YidC to the SecYEG translocon expands the global view on the SecYEG interactome in Escherichia coli
2019
A statistical framework for analyzing deep mutational scanning data
2017
Protein interactions in human pathogens revealed through deep learning
2024 StandoutNobel
Single particle electron cryo-microscopy of a mammalian ion channel
2014 StandoutNobel
Recognition of herpesviruses by the innate immune system
2011
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
2019 StandoutNobel
Amino acid signalling upstream of mTOR
2013
Empirical Scoring Functions for Structure-Based Virtual Screening: Applications, Critical Aspects, and Challenges
2018
A single copy of SecYEG is sufficient for preprotein translocation
2011
SignalP 5.0 improves signal peptide predictions using deep neural networks
2019 Standout
Membrane protein assembly into Nanodiscs
2009
Traffic Jam at the Bacterial Sec Translocase: Targeting the SecA Nanomotor by Small-Molecule Inhibitors
2011
Biophysical characterization of membrane proteins in nanodiscs
2012
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
Structure of a complex of the ATPase SecA and the protein-translocation channel
2008 Nature
The Bacterial Cell Envelope
2010 Standout
Activation and regulation of the inflammasomes
2013 Standout
YidC Occupies the Lateral Gate of the SecYEG Translocon and Is Sequentially Displaced by a Nascent Membrane Protein
2013
The molecular machinery of regulated cell death
2019 Standout
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Dynamics of SecY Translocons with Translocation-Defective Mutations
2010
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
Biochemical regulation of the inflammasome
2012
Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
2011
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
2007 Nature
Drug repurposing: progress, challenges and recommendations
2018 Standout
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
2010 Standout
Translocation of proteins through the Sec61 and SecYEG channels
2009
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Structures of membrane proteins
2010 StandoutNobel
Assessment of scoring functions and in silico parameters for AChE-ligand interactions as a tool for predicting inhibition potency
2019
Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores
2013 StandoutNobel
Sterile inflammation: sensing and reacting to damage
2010 Standout
A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins
2012 StandoutNobel
Nanodiscs as a New Tool to Examine Lipid–Protein Interactions
2012
The roles of interferon-inducible p200 family members IFI16 and p204 in innate immune responses, cell differentiation and proliferation
2014
Membrane mimetic systems in CryoEM: keeping membrane proteins in their native environment
2019 StandoutNobel
Phenylpropanoid Biosynthesis
2009 Standout
Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs
2009
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
IFI16 is an innate immune sensor for intracellular DNA
2010
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
Small molecule modulators of Wnt/β-catenin signaling
2013
Light‐Induced Control of Protein Translocation by the SecYEG Complex
2010 StandoutNobel
An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
2013
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
2010 StandoutNobel
Circulating tumor DNA alterations in patients with metastatic castration‐resistant prostate cancer
2019
The action of cardiolipin on the bacterial translocon
2010
Exploring the nature of the translocon-assisted protein insertion
2012 StandoutNobel
Amphipols, Nanodiscs, and Fluorinated Surfactants: Three Nonconventional Approaches to Studying Membrane Proteins in Aqueous Solutions
2010
Light‐Induced Control of Protein Translocation by the SecYEG Complex
2010 StandoutNobel
Probing the SecYEG translocation pore size with preproteins conjugated with sizable rigid spherical molecules
2011 StandoutNobel
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy
2013
Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches
2016 Standout
The Hydrophobic Core of the Sec61 Translocon Defines the Hydrophobicity Threshold for Membrane Integration
2010
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug
2014 Standout
The Candidatus Liberibacter–Host Interface: Insights into Pathogenesis Mechanisms and Disease Control
2017 Standout
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
The nanodisc: a novel tool for membrane protein studies
2009
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
2018 Standout
On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes
2010 StandoutNobel
Works of Kush Dalal being referenced
Moving Towards Precision Urologic Oncology: Targeting Enzalutamide-resistant Prostate Cancer and Mutated Forms of the Androgen Receptor Using the Novel Inhibitor Darolutamide (ODM-201)
2017
Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA
2007
The maltose ABC transporter: Action of membrane lipids on the transporter stability, coupling and ATPase activity
2013
The SecY complex: conducting the orchestra of protein translocation
2011
Reconstitution of the SecY Translocon in Nanodiscs
2010
RPA nucleic acid-binding properties of IFI16-HIN200
2008
Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
2012
Structure, Binding, and Activity of Syd, a SecY-interacting Protein
2009
Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase
2012
The SecY complex forms a channel capable of ionic discrimination
2009
Best Practices of Computer-Aided Drug Discovery: Lessons Learned from the Development of a Preclinical Candidate for Prostate Cancer with a New Mechanism of Action
2017
SecYEG activates GTPases to drive the completion of cotranslational protein targeting
2013