Citation Impact

Citing Papers

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2μ–cargo complexes
2006
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
2004 StandoutNobel
GROα regulates human embryonic stem cell self-renewal or adoption of a neuronal fate
2011
Modulation of Integrin Activation by an Entropic Spring in the β-Knee
2010 StandoutNobel
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
The Active Conformation of β-Arrestin1
2007 StandoutNobel
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor
2008 StandoutNobel
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Filopodia: molecular architecture and cellular functions
2008 Standout
DNA‐Coated AFM Cantilevers for the Investigation of Cell Adhesion and the Patterning of Live Cells
2008 StandoutNobel
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
2008 Nature
Role of activation of PIP5Kγ661 by AP‐2 complex in synaptic vesicle endocytosis
2007
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Focal adhesion kinase: in command and control of cell motility
2005 Standout
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Activation of a vinculin‐binding site in the talin rod involves rearrangement of a five‐helix bundle
2004
A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head
2005
Control of motile and invasive cell phenotypes by focal adhesion kinase
2004
BTK Regulates PtdIns-4,5-P2 Synthesis
2003
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking
2004 Nature
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Nanoparticles functionalised with reversible molecular and supramolecular switches
2010 StandoutNobel
β-Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation
2002
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
β-Arrestin 2 Functions as a G-Protein-coupled Receptor-activated Regulator of Oncoprotein Mdm2
2003
NEW EMBO MEMBER'S REVIEW: The integrin-actin connection, an eternal love affair
2003
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
2006
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Lipid Bilayer Simulations of CXCR4 with Inverse Agonists and Weak Partial Agonists
2003
Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2
2004 StandoutNobel
G‐protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal
2004 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
2009 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Membrane curvature and mechanisms of dynamic cell membrane remodelling
2005 StandoutNature
Subcellular Localization of β-Arrestins Is Determined by Their Intact N Domain and the Nuclear Export Signal at the C Terminus
2003
Activation of Type I Phosphatidylinositol 4-Phosphate 5-Kinase Isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
2004
The Exocyst Complex in Health and Disease
2016
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
2008
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
The role of senescent cells in ageing
2014 StandoutNature
CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3
2011
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Stable Interaction between β-Arrestin 2 and Angiotensin Type 1A Receptor Is Required for β-Arrestin 2-mediated Activation of Extracellular Signal-regulated Kinases 1 and 2
2004 StandoutNobel
Integrin signaling to the actin cytoskeleton
2003
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
Membrane Ruffling Requires Coordination between Type Iα Phosphatidylinositol Phosphate Kinase and Rac Signaling
2003
β-Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between β-Arrestin and CXCR4
2000
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
The talin–tail interaction places integrin activation on FERM ground
2004
Giant Unilamellar Vesicles Containing Phosphatidylinositol(4,5)bisphosphate: Characterization and Functionality
2008
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Allosteric binding sites on cell-surface receptors: novel targets for drug discovery
2002
Rho and Rho-kinase Mediate Thrombin-induced Phosphatidylinositol 4-Phosphate 5-Kinase Trafficking in Platelets
2004
Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3
2004
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals
2004
Exorcising the Exocyst Complex
2012
Cryo-electron tomography reveals conserved features of doublet microtubules in flagella
2011
Coordinated Activation of the Nuclear Ubiquitin Ligase Cul3-SPOP by the Generation of Phosphatidylinositol 5-Phosphate
2008
Phosphoinositide regulation of clathrin-mediated endocytosis
2005
The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex
2014
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Talin forges the links between integrins and actin
2003
Integrin activation
2004
International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
2000 Standout
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement
2007
Molecular Mechanics and Dynamics of Leukocyte Recruitment During Inflammation
2005
Phosphoinositide regulation of clathrin-mediated endocytosis
2005
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Robust excitons inhabit soft supramolecular nanotubes
2014 StandoutNobel
PIP5KIγ is required for cardiovascular and neuronal development
2007
Critical role of PIP5KIγ87 in InsP3-mediated Ca2+ signaling
2004
Type Iγ PIP Kinase Is a Novel Uropod Component that Regulates Rear Retraction during Neutrophil Chemotaxis
2007
Regulation of the interaction between PIPKIγ and talin by proline-directed protein kinases
2005
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Loss of PIP5KIβ demonstrates that PIP5KI isoform-specific PIP 2 synthesis is required for IP 3 formation
2008
The Tail of Integrins, Talin, and Kindlins
2009 Science
Phosphatidylinositol Phosphate Kinase Type 1γ and β1-Integrin Cytoplasmic Domain Bind to the Same Region in the Talin FERM Domain
2003
Mechanisms that regulate adaptor binding to β-integrin cytoplasmic tails
2008
A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate
2008
The LIM Protein Ajuba Regulates Phosphatidylinositol 4,5-Bisphosphate Levels in Migrating Cells through an Interaction with and Activation of PIPKIα
2005
Adhesion-Dependent Cell Mechanosensitivity
2003
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma
2004
The Exocyst at a Glance
2015
Phosphatidylinositol phosphate 5-kinase Iβ recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis
2003
Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes
2010
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ
2003
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel

Works of Kun Ling being referenced

Tyrosine phosphorylation of type Iγ phosphatidylinositol phosphate kinase by Src regulates an integrin–talin switch
2003
The BBSome controls IFT assembly and turnaround in cilia
2012
Direct binding of β‐arrestins to two distinct intracellular domains of the δ opioid receptor
2001
A Conspicuous Connection: Structure Defines Function for the Phosphatidylinositol-Phosphate Kinase Family
2007
Phosphatidylinositol Phosphate Kinase Type Iγ Directly Associates with and Regulates Shp-1 Tyrosine Phosphatase
2005
Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions
2002 Nature
Movin' on up: the role of PtdIns(4,5)P2 in cell migration
2006
Type Iγ661 Phosphatidylinositol Phosphate Kinase Directly Interacts with AP2 and Regulates Endocytosis
2006
Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells
2012
Molecular Dynamics Simulations on SDF-1α: Binding with CXCR4 Receptor
2003
Five-transmembrane domains appear sufficient for a G protein-coupled receptor: Functional five-transmembrane domain chemokine receptors
1999
Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB
2017
Type Iγ phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration
2007
Anti-HIV Agent Trichosanthin Enhances the Capabilities of Chemokines to Stimulate Chemotaxis and G Protein Activation, and This Is Mediated through Interaction of Trichosanthin and Chemokine Receptors
1999
E-Cadherin-Mediated Cell–Cell Contact Is Critical for Induced Pluripotent Stem Cell Generation  
2010
The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis
2010
Type Iγ phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with μ1B adaptin
2007
An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization
2011
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2026