Kosuke Okamoto

SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors

Nicotine Chemistry, Metabolism, Kinetics and Biomarkers

Sputum Biomarkers of Inflammation in Cystic Fibrosis Lung Disease

Phospholipase A2 subclasses in acute respiratory distress syndrome

Cystic fibrosis

Association between Pulmonary Function and Sputum Biomarkers in Cystic Fibrosis

The Role of Mucus in Cough Research

Biological roles of glycans

Pharmacology of Airway Goblet Cell Mucin Release

Neutrophil extracellular traps in immunity and disease

Mucus and Mucins

Monitoring Respiratory Disease Severity in Cystic Fibrosis

Biomarkers of tobacco exposure or harm: Application to clinical and epidemiological studies

Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity

Airway Mucus Function and Dysfunction

Cellular and Molecular Biology of Airway Mucins

Sputum Biomarkers of Inflammation and Lung Function Decline in Children with Cystic Fibrosis

Differentiation of chronic sinus diseases by measurement of inflammatory mediators

Release of Cystic Fibrosis Airway Inflammatory Markers from Pseudomonas aeruginosa–Stimulated Human Neutrophils Involves NADPH Oxidase-Dependent Extracellular DNA Trap Formation

Phospholipase A₂Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention

Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

Antimicrobial Resistance in ESKAPE Pathogens

Pulmonary Function Is Negatively Correlated With Sputum Inflammatory Markers and Cough Clearability in Subjects With Cystic Fibrosis But Not Those With Chronic Bronchitis

Pseudomonas aeruginosa alginate is a potent secretagogue in the isolated ferret trachea

Hyperosmolar Solutions Stimulate Mucus Secretion in the Ferret Trachea

Vasoactive intestinal peptide stimulates mucus secretion, but nitric oxide has no effect on mucus secretion in the ferret trachea

Respiratory-Related Quality of Life: Relation to Pulmonary Function, Functional Exercise Capacity, and Sputum Biophysical Properties

Sputum processing for evaluation of inflammatory mediators

Sputum processing for evaluation of inflammatory mediators

Secretory phospholipases A₂stimulate mucus secretion, induce airway inflammation, and produce secretory hyperresponsiveness to neutrophil elastase in ferret trachea