Citation Impact
Citing Papers
Prospective identification of tumorigenic breast cancer cells
2003 Standout
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Redox Regulation of Cell Survival
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulation of Cdc42-mediated morphological effects: a novel function for p53
2002
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
A High-Resolution STS, EST, and Gene-Based Physical Map of the Hereditary Paraganglioma Region on Chromosome 11q23
1997
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
2000 StandoutNobel
A Polymer-Based, Paclitaxel-Eluting Stent in Patients with Coronary Artery Disease
2004 Standout
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
Molecular mechanisms of drug resistance
2005
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Nonalcoholic Fatty Liver Disease
2002 Standout
Genetic instabilities in human cancers
1998 StandoutNature
Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning
2018 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
Genomic instability in Ip and human malignancies
1996
p53 mediates density‐dependent growth arrest
2004
Genomic organization and precise physical location of protein phosphatase 2A regulatory subunit A beta isoform gene on chromosome band 11q23
1998
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
Refinement of the LOH region 1 at 11q23.1 deleted in human breast carcinomas and sublocalization of 11 expressed sequence tags within the refined region
1999
Chromosomes, 11q and cancer: a review
1999
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The antioxidant function of the p53 tumor suppressor
2005
Cancer invasion and resistance: interconnected processes of disease progression and therapy failure
2011
Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer
1997
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
1999
Potent Prostaglandin A1 Analogs That Suppress Tumor Cell Growth through Induction of p21 and Reduction of Cyclin E
1998 StandoutNobel
Cytogenetic Analysis of Colorectal Adenomas
1998
Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer
2000
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Molecular themes in oncogenesis
1991 StandoutNobel
Allelotype of head and neck paragangliomas: Allelic imbalance is confined to the long arm of chromosome 11, the site of the predisposing locus PGL
1994
Regulation and Mechanisms of Mammalian Gene Amplification
1993
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
Gastric cancer
2020 Standout
The Inflammasomes
2010 Standout
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
1994 Standout
Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics
2014
Recent progress in understanding mechanisms of mammalian DNA amplification
1989
The Tumor Suppressor Protein p16 and the Human Papillomavirus Oncoprotein-58 E7 Are Naturally Occurring Lysine-less Proteins That Are Degraded by the Ubiquitin System
2004 StandoutNobel
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
2001
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
1991 Standout
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Mutagenic, teratogenic and pharmacokinetic properties of cyclophosphamide and some of its deuterated derivatives
1982
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
2010
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.
1986
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells
1984 Nature
Cancer Cell Cycles
1996 StandoutScience
Ataxia-telangiectasia and cellular responses to DNA damage.
1995
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
Multidrug Resistance of DNA-Mediated Transformants is Linked to Transfer of the Human mdr1 Gene
1986
Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines
1985 Nature
Structure and expression of the human MDR (P-glycoprotein) gene family.
1989
The retinoblastoma protein and cell cycle control
1995 Standout
Gene amplification in cultured animal cells
1984
A Study of Occupational Exposure to Antineoplastic Drugs and Fetal Loss in Nurses
1985 Standout
Genetic and biochemical characterization of multidrug resistance
1985
Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines
1983 Science
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53‐null mammary epithelial cell mode .
2000
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.
2000
A weak germ-line excision mutation blocks developmentally controlled amplification of the rDNA minichromosome of Tetrahymena thermophila.
1994 StandoutNobel
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
1986 Standout
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis.
2000
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.
1994
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.
1987 Standout
Fine mapping of an imprinted gene for familial nonchromaffin paragangliomas, on chromosome 11q23.
1997
Fluorodeoxyuridine Modulates Cellular Expression of the DNA Base Excision Repair Enzyme Uracil-DNA Glycosylase
2006
Works of Kopnin Bp being referenced
Repression of Sestrin Family Genes Contributes to Oncogenic Ras-Induced Reactive Oxygen Species Up-regulation and Genetic Instability
2007
Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil
2002
Regularities of karyotypic evolution during stepwise amplification of genes determining drug resistance
1992
Enhanced expression of 1p32 and 1p22 fragile sites in lymphocytes in cutaneous malignant melanomas
1992
p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling
2001
Cloning and characterization of DNA sequences amplified in multidrug-resistant Djungarian hamster and mouse cells
1987
p53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints
1999
Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization
2000
Karyotype pecularities of human colorectal adenocarcinomas
1991
Changes in p53 expression can modify cell shape of ras-transformed fibroblasts and epitheliocytes
1997
11q deletions in human colorectal carcinomas: Cytogenetics and restriction fragment length polymorphism analysis
1993
Chromosome changes caused by alterations of p53 expression
1996
Cytogenetic toxicity of cyclophosphamide and its metabolites in vitro
1980
Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation
1998
Distinct effects of various p53 mutants on differentiation and viability of human K562 leukemia cells.
1997
Gene amplification in Djungarian hamster cell lines possessing decreased plasma membrane permeability for colchicine and some other drugs
1985
[Effect of on various cell lines of p53 cDNA, expressed under the control of an exogenous homologous promotor].
1995
Specific karyotypic alterations in colchicine-resistant cells
1981