Citation Impact

Citing Papers

Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
2018
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Effect of a zinc l-carnosine compound on acid-induced injury in canine gastric mucosa ex vivo
2012
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion
2009
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Ulcerative Colitis
2011 Standout
Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia
1995
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Is lactate an undervalued functional component of fermented food products?
2015
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
2014
Antisecretory and Antiulcer Effects of Ebselen, a Seleno-Organic Compound, in Rats
1993
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
1996 StandoutNature
Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects
2008
Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations?
2006
Bifunctional Hydrogen‐Bond Donors That Bear a Quinazoline or Benzothiadiazine Skeleton for Asymmetric Organocatalysis
2011
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
Biochemistry and pharmacology of endovanilloids
2007
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
2009
Inflammation Drives Dysbiosis and Bacterial Invasion in Murine Models of Ileal Crohn’s Disease
2012
Role of the Microbiota in Immunity and Inflammation
2014 Standout
COX-2 inhibition and prevention of cancer
2001
Protective Effect of Ebselen, a Seleno-Organic Compound, Against the Progression of Acute Gastric Mucosal Lesions Induced by Compound 48/80, a Mast Cell Degranulator, in Rats
2002
Alogliptin: a new, highly selective dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
2009
pH-sensitive microsphere delivery increases oral bioavailability of calcitonin
2004
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Necrotizing Enterocolitis
2011 Standout
Coated Oral 5-Aminosalicylic Acid Therapy for Mildly to Moderately Active Ulcerative Colitis
1987 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Protective role of vanilloid receptor type 1 in HCl‐induced gastric mucosal lesions in rats
2004
Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis
2006
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease
2007
The TRPV1 receptor and nociception
2006
Extensive co‐occurrence of substance P and dynorphin in striatal projection neurons: An evolutionarily conserved feature of basal ganglia organization
1990
Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
2009
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
1995 StandoutNobel
A TRPV Channel Modulates C. elegans Neurosecretion, Larval Starvation Survival, and Adult Lifespan
2008
The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function
2003 Standout
Structural and Morphometric Analysis of Murine Small Intestine after Indomethacin Administration
1993
The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia
2010
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Polaprezinc Attenuates Helicobacter pylori‐Associated Gastritis in Mongolian Gerbils
2002
Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice
2005
Asymmetric Synthesis of 3‐Amino‐δ‐lactams and Benzo[a]quinolizidines by Catalytic Cyclization Reactions Involving Azlactones
2009
Mammalian G-protein function in vivo: New insights through altered gene expression
2006
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
2014 Standout
Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults
2003 Standout
Hybrid porous solids: past, present, future
2007 Standout
Physiology and Pathophysiology of Carnosine
2013 Standout
3d Transition Metals for C–H Activation
2018 Standout
Oxidation of Alcohols with Molecular Oxygen on Solid Catalysts
2004 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Angiotensin Blockade Inhibits Activation of Mitogen-Activated Protein Kinases in Rat Balloon-Injured Artery
1998 StandoutNobel
Catalysis by Heteropoly Acids and Multicomponent Polyoxometalates in Liquid-Phase Reactions
1998 Standout
Emerging Role of Sensory Perception in Aging and Metabolism
2016
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Alogliptin: a new addition to the class of DPP-4 inhibitors
2009
IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential
2012
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Monodisperse Double Emulsions Generated from a Microcapillary Device
2005 StandoutScience
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Dipeptidyl Peptidase IV and Its Inhibitors: Therapeutics for Type 2 Diabetes and What Else?
2013
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Effect of NC-1300-0-3 on Healing of Acetic Acid-Induced Gastric Ulcers in Rats
1993
Purification, cloning, and primary structure of an enantiomer-selective amidase from Brevibacterium sp. strain R312: structural evidence for genetic coupling with nitrile hydratase
1990
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Polymer microspheres for controlled drug release
2004
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Inflammatory Bowel Disease
2010 Standout
Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation
2005
Sucralfate treatment of nonsteroidal anti-inflammatory drug-induced gastrointestinal symptoms and mucosal damage
1987
Hydrotalcite-type anionic clays: Preparation, properties and applications.
1991 Standout
Total synthesis of BE-23254, a chlorinated angucycline antibiotic
2005
Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV
2010
Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity
1987
Pd(ii)-catalyzed β-C–H arylation of O-methyl ketoximes with iodoarenes
2016
IARC Handbooks of Cancer Prevention
2003
Opposing functions of IKKβ during acute and chronic intestinal inflammation
2008
Chiral Allenes via Alkynylogous Mukaiyama Aldol Reaction
2016 StandoutNobel
Prophylaxis of Early Adrenal Insufficiency to Prevent Bronchopulmonary Dysplasia: A Multicenter Trial
2004
Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
2014 Standout
Recent Advances in the Synthesis and Application of Layered Double Hydroxide (LDH) Nanosheets
2012 Standout
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Catalytic Asymmetric Protonation of Silyl Ketene Imines
2013 StandoutNobel
Vanilloid receptor TRPV1: hot on the tongue and inflaming the colon
2004
Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man.
1986
Aspirin and the Stomach
1986
Copper-Catalyzed Cascade Amination Route to N-Aryl Benzimidazoquinazolinones
2016
Organoselenium and Organotellurium Compounds:  Toxicology and Pharmacology
2004 Standout
The Cerebellum-Specific Munc13 Isoform Munc13-3 Regulates Cerebellar Synaptic Transmission and Motor Learning in Mice
2001 StandoutNobel

Works of Koji Takeuchi being referenced

The role and interactions of nitric oxide (NO), carbon monoxide (CO), and prostanoids in the pathogenesis of postoperative ileus in rats
2004
Prostaglandin E Inhibits Indomethacin-Induced Gastric Lesions through EP-1 Receptors
2001
Diethyldithiocarbamate, a Superoxide Dismutase Inhibitor, Reduces Indomethacin-lnduced Gastric Lesions in Rats
1996
Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys
2008
Role of nitric oxide in pathogenesis of gastric mucosal damage induced by compound in rats
1997
Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid
2009
Lithium increases dynorphin A(1–8) and prodynorphin mRNA levels in the basal ganglia of rats
1988
A continuous monitoring of mucosal integrity and secretory activity in rat stomach: A preparation using a lucite chamber.
1989
Gastric Mucosal Defense and Cytoprotection: Bench to Bedside
2008
HSP70 Confers Protection against Indomethacin-Induced Lesions of the Small Intestine
2009
Prophylactic Effect of Monosodium Glutamate on NSAID-Induced Enteropathy in Rats
2014
Effect of Lafutidine, a Histamine H2-Receptor Antagonist, on Gastric Mucosal Blood Flow and Duodenal HCO3− Secretion in Rats: Relation to Capsaicin-Sensitive Afferent Neurons
2002
Polaprezinc Exerts a Salutary Effect on Impaired Healing of Acute Gastric Lesions in Diabetic Rats
2000
Chronic administration of alogliptin, a novel, potent, and highly selective dipeptidyl peptidase-4 inhibitor, improves glycemic control and beta-cell function in obese diabetic ob/ob mice
2008
Role of Prostaglandin E Receptor Subtypes in Gastroduodenal HCO3 - Secretion
2005
Genetic Evidence for a Protective Role for Heat Shock Factor 1 and Heat Shock Protein 70 against Colitis
2007
Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet β cells modulates insulin secretion in rats
2004
Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protection
2003
Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism
2016
Novel angucycline compound with both antigastrin- and gastric mucosal protective-activities
1998
The role of capsaicin-sensitive sensory neurons in healing of HCl-lnduced gastric mucosal lesions in rats
1994
Role of Cyclooxygenase (COX)-1 and COX-2 Inhibition in Nonsteroidal Anti-Inflammatory Drug-Induced Intestinal Damage in Rats: Relation to Various Pathogenic Events
2002
Delayed Healing of Acetic Acid-Induced Gastric Ulcers in Rats by Indomethacin
1989
Protective Effect of Lactulose on Dextran Sulfate Sodium-Induced Colonic Inflammation in Rats
2004
Stimulation by Capsaicin of Duodenal HCO3− Secretion via Afferent Neurons and Vanilloid Receptors in Rats: Comparison with Acid-Induced HCO3− Response
2003
Aggravation by Selective COX-1 and COX-2 Inhibitors of Dextran Sulfate Sodium (DSS)-Induced Colon Lesions in Rats
2007
Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent
2007
Gastric mucosal damage induced by compound 48/80: Roles of serotonin and nitric oxide
1998
The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
2010
Discovery of Alogliptin:  A Potent, Selective, Bioavailable, and Efficacious Inhibitor of Dipeptidyl Peptidase IV
2007
Prostaglandin E receptor subtypes involved in stimulation of gastroduodenal bicarbonate secretion in rats and mice.
1999
Effects of various agents on prednisolone-induced gastric lesions in rats.
1985
Mechanisms by which endogenous glucocorticoid protects against indomethacin-induced gastric injury in rats
2002
Application of Eudragit P-4135F for the delivery of ellagic acid to the rat lower small intestine
2001
Abnormal Phosphatidylinositol‐Cycle of Platelet Membrane in Schizophrenia–––A Preliminary Study
1984
A New Model of Duodenal Ulcers Induced in Rats by Indomethacln Plus Histamine
1986
Nitrile hydratase of Pseudomonas chlororaphis B23
1987
Requirements for Restitution of the Surface Epithelium of Frog Stomach After Mucosal Injury
1985
Gastric hyperemic response induced by acid back-diffusion in rat stomachs following barrier disruption -- relation to vanilloid type-1 receptors.
2002
Effect of polaprezinc on impaired healing of chronic gastric ulcers in adjuvant-induced arthritic rats--role of insulin-like growth factors (IGF)-1.
2001
Discovery of Alogliptin: A Potent, Selective, Bioavailable, and Efficacious Inhibitor of Dipeptidyl Peptidase IV
2008
Effects of Cyclooxygenase-2 Selective and Nitric Oxide-Releasing Nonsteroidal Antiinflammatory Drugs on Mucosal Ulcerogenic and Healing Responses of the Stomach
1998
Effects of an antiulcer drug, sucralfate (A basic aluminum salt of sulfated disaccharide), on experimental gastric lesions and gastric secretion in rats
1983
Effects of cimetidine and atropine sulfate in gastric secretion and healing of gastric and duodenal ulcers in rats
1977
Rankless by CCL
2026