Standout Papers
Citation Impact
Citing Papers
Augmenting neurotransmitter release by enhancing the apparent Ca 2+ affinity of synaptotagmin 1
2005 StandoutNobel
Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
2006 StandoutNobel
A conformational switch in the Piccolo C2A domain regulated by alternative splicing
2003 StandoutNobel
Role of yeast in cancer research
1992 StandoutNobel
Structural views of phosphoinositide-specific phospholipase C: signalling the way ahead
1996
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor
2008 StandoutNobel
Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding
1999
An unusual C2-domain in the active-zone protein piccolo: implications for Ca2+ regulation of neurotransmitter release
2001
The Top Loops of the C2 Domains from Synaptotagmin and Phospholipase A2 Control Functional Specificity
2001 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
RECEPTOR-G PROTEIN SIGNALING IN YEAST
1991
Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ
1996 Nature
Expression and Purification of the Saccharomyces cerevisiae α-Factor Receptor (Ste2p), a 7-Transmembrane-segment G Protein-coupled Receptor
1997
Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation
1995 StandoutNobel
Characterization of the adenosine receptor in microvascular coronary endothelial cells
1994
The Presynaptic Active Zone
2012 StandoutNobel
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
β-Arrestin-mediated ADP-ribosylation Factor 6 Activation and β2-Adrenergic Receptor Endocytosis
2001 StandoutNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Adenosine A2 receptor-mediated excitatory actions on the nervous system
1996
High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity
1997
C2-domains, Structure and Function of a Universal Ca2+-binding Domain
1998 StandoutNobel
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
β2-Adrenergic Receptor Signaling and Desensitization Elucidated by Quantitative Modeling of Real Time cAMP Dynamics
2007 StandoutNobel
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Synaptotagmins: Why So Many?
2002 StandoutNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Human β2‐adrenergic receptor produced in stably transformed insect cells is functionally coupled via endogenous GTP‐binding protein to adenylyl cyclase
1993
Seven-transmembrane receptors
2002 StandoutNobel
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
RGS Proteins and Signaling by Heterotrimeric G Proteins
1997
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Cloning and expression of a widely distributed (type IV) adenylyl cyclase.
1991 StandoutNobel
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
1994 StandoutNobel
Receptors for Purines and Pyrimidines
1998 Standout
Regulatory recruitment of signalling molecules to the cell membrane by pleckstrinhomology domains
1997
Differential but convergent functions of Ca 2+ binding to synaptotagmin-1 C 2 domains mediate neurotransmitter release
2009 StandoutNobel
Mechanism of GTP hydrolysis by G-protein alpha subunits.
1994 StandoutNobel
Receptor nomenclature
1996
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C
2000
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.
1993 StandoutNobel
Role of Electrostatic and Hydrophobic Interactions in Ca2+-Dependent Phospholipid Binding by the C2A-Domain From Synaptotagmin I
2002 StandoutNobel
The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits.
1992 StandoutNobel
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma
1992 StandoutNobel
Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family.
1994 StandoutNobel
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
Activation of phospholipase C-beta 2 mutants by G protein alpha q and beta gamma subunits.
1993 StandoutNobel
Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits.
1993 StandoutNobel
Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling
1998 StandoutNobel
Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin.
1992 StandoutNobel
Ultrasensitive magnetic biosensor for homogeneous immunoassay
2000 StandoutNobel
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
1994 StandoutNobel
Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
2010 StandoutNobel
Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.
1994 StandoutNobel
Agonist-modulated palmitoylation of beta 2-adrenergic receptor in Sf9 cells.
1992
Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling
1998 StandoutNobel
Coupling of a transfected human brain A1 adenosine receptor in CHO‐K1 cells to calcium mobilisation via a pertussis toxin‐sensitive mechanism
1994
Lipid modifications of G proteins: alpha subunits are palmitoylated.
1993 StandoutNobel
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
1994
Receptor regulation of G-protein palmitoylation.
1994 StandoutNobel
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Works of Klim King being referenced
Phosphatidylinositol 4,5-Bisphosphate Binding to the Pleckstrin Homology Domain of Phospholipase C-δ1 Enhances Enzyme Activity
1996
Activation of Phospholipase C δ1 through C2 Domain by a Ca2+-Enzyme-Phosphatidylserine Ternary Complex
1999
Molecular Cloning of a Novel Adenosine Receptor Gene from Rat Brain
1992
Cloning and Identification of Amino Acid Residues of Human Phospholipase Cδ1 Essential for Catalysis
1995
Positive Charge at Position 549 Is Essential for Phosphatidylinositol 4,5-Bisphosphate-hydrolyzing but Not Phosphatidylinositol-hydrolyzing Activities of Human Phospholipase C δ1
1996
Control of Yeast Mating Signal Transduction by a Mammalian β 2 -adrenergic Receptor and G s α Subunit
1990 StandoutScienceNobel