Standout Papers
- Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques (2009)
- The Simian Immunodeficiency Virus ΔnefVaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4+T Cells and Elicits a Local Perforin-Positive CD8+T-Cell Response (2002)
- Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus (2004)
- Atraumatic Oral Spray Immunization with Replication-Deficient Viral Vector Vaccines (2007)
- Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells (2010)
- CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo (2005)
- The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells (2008)
- Induction of neutralising antibodies restricts the use of human granulocyte/macrophage colony stimulating factor for vaccine studies in rhesus macaques (2004)
- Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus (2006)
Citation Impact
Citing Papers
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Metagenomic Analyses of Viruses in Stool Samples from Children with Acute Flaccid Paralysis
2009
A macaque model of HIV-1 infection
2009
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
CTLA-4-Mediated Inhibition of Early Events of T Cell Proliferation
1999 StandoutNobel
Cutting Edge: Polyinosinic:Polycytidylic Acid Boosts the Generation of Memory CD8 T Cells through Melanoma Differentiation-Associated Protein 5 Expressed in Stromal Cells
2010
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Viral load in tissues during the early and chronic phase of non‐pathogenic SIVagm infection
2004 StandoutNobel
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Virological assessment of hospitalized patients with COVID-2019
2020 StandoutNature
Developments in Quantitative PCR
1998
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor
2004
Basic Amino Acid Residues in the V3 Loop of Simian Immunodeficiency Virus Envelope Alter Viral Coreceptor Tropism and Infectivity but Do Not Allow Efficient Utilization of CXCR4 as Entry Cofactor
2001
Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts
2012
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
Reverse Transcriptase and Corresponding Activity-Blocking Antibody for Monitoring SIV ℠ Infection in Macaques
1997
Differences in early virus loads with different phenotypic variants of HIV-1 and SIVcpz in chimpanzees
2001
A Blueprint for HIV Vaccine Discovery
2012
NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
2018
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates
2010 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses
2016 Standout
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
The origin and function of tumor-associated macrophages
1992
Radiation-induced changes in gene expression and distribution of atrial natriuretic peptide (ANP) in different anatomical regions of the rat heart
2002
Exosomes: Therapy delivery tools and biomarkers of diseases
2017
Cancer-related inflammation
2008 StandoutNature
Dendritic cell subsets in primary and secondary T cell responses at body surfaces
2009
Evaluation of antiretrovirals in animal models of HIV infection
2009
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
From SARS to MERS, Thrusting Coronaviruses into the Spotlight
2019
Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice
2010 StandoutNobel
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Potentiation of Simian Immunodeficiency Virus (SIV)-Specific CD4+ and CD8+ T Cell Responses by a DNA-SIV and NYVAC-SIV Prime/Boost Regimen
2001
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Increased Macrophage Infection upon Subcutaneous Inoculation of Rhesus Macaques with Simian Immunodeficiency Virus-Loaded Dendritic Cells or T Cells but Not with Cell-Free Virus
2002 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Semen Exosomes Promote Transcriptional Silencing of HIV-1 by Disrupting NF-κB/Sp1/Tat Circuitry
2018
Fc receptors in antibody‐dependent enhancement of viral infections
2015
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
The Cytoplasmic Tail of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Contains a Novel Endoplasmic Reticulum Retrieval Signal That Binds COPI and Promotes Interaction with Membrane Protein
2006
Routes and mechanisms of extracellular vesicle uptake
2014 Standout
Effects of in Vivo Cd8+ T Cell Depletion on Virus Replication in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine
1999
Simian Immunodeficiency Virus Disease Course Is Predicted by the Extent of Virus Replication during Primary Infection
1999
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.
1993 Standout
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
2009
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen
1999
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys
2000 StandoutNobel
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies
2013
Molecular pathology of emerging coronavirus infections
2014
DC-SIGN and DC-SIGNR Interact with the Glycoprotein of Marburg Virus and the S Protein of Severe Acute Respiratory Syndrome Coronavirus
2004
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
2004
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Maintenance of Large Numbers of Virus-Specific CD8+ T Cells in HIV-Infected Progressors and Long-Term Nonprogressors
2000
High Levels of Viral Replication Contrast with Only Transient Changes in CD4+and CD8+Cell Numbers during the Early Phase of Experimental Infection with Simian Immunodeficiency Virus SIVmnd-1 inMandrillus sphinx
2002 StandoutNobel
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells
2000 StandoutNobel
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
Tumor-induced immune dysfunction: the macrophage connection
1998
The rate of progression to AIDS is independent of virus dose in simian immunodeficiency virus-infected macaques
2000
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry
2005
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
2011
Interleukin 7 induces CD4+ T cell-dependent tumor rejection.
1991
Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK
2005
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Quantitative or semi-quantitative PCR: reality versus myth.
1992
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection
2000
Endogenously Expressed nef Uncouples Cytokine and Chemokine Production from Membrane Phenotypic Maturation in Dendritic Cells
2002 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells
1999
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
2005
Chemokine receptors and human immunodeficiency virus infection
1998
Impact of Viral Factors on Very Early In Vivo Replication Profiles in Simian Immunodeficiency Virus SIVagm-Infected African Green Monkeys
2005 StandoutNobel
Works of Klaus Überla being referenced
Analysis of cytokine mRNA levels in interleukin‐4‐transgenic mice by quantitative polymerase chain reaction
1992
Croup Is Associated with the Novel Coronavirus NL63
2005
Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands
2009
Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques
2009 StandoutNobel
Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus
2008
Interleukin‐4‐mediated tumor suppression in nude mice involves interferon‐γ
1992
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV‐infected rhesus monkeys undergoing antiretroviral therapy
2006
SIV/HIV-1 Hybrid Virus Expressing the Reverse Transcriptase Gene of HIV-1 Remains Sensitive to HIV-1-Specific Reverse Transcriptase Inhibitors After Passage in Rhesus Macaques
1997
The HIV-1 Rev Protein Enhances Encapsidation of Unspliced and Spliced, RRE-Containing Lentiviral Vector RNA
2012
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus
2006 StandoutNobel
Suppression of Acute Viremia by Short-Term Postexposure Prophylaxis of Simian/Human Immunodeficiency Virus SHIV-RT-Infected Monkeys with a Novel Reverse Transcriptase Inhibitor (GW420867) Allows for Development of Potent Antiviral Immune Responses Resulting in Efficient Containment of Infection
2000
Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques
2000
Characterization of Virus Isolates by Particle-Associated Nucleic Acid PCR
2005
Env-Independent Protection Induced by Live, Attenuated Simian Immunodeficiency Virus Vaccines
1998
Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry
1997
S Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Mediates Entry into Hepatoma Cell Lines and Is Targeted by Neutralizing Antibodies in Infected Patients
2004
Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors.
1995
Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer.
1991
Nuclear RNA Export and Packaging Functions of HIV-1 Rev Revisited
2010
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells
2010 StandoutNobel
Generation of competitor DNA fragments for quantitative PCR.
1991
The Simian Immunodeficiency Virus ΔnefVaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4+T Cells and Elicits a Local Perforin-Positive CD8+T-Cell Response
2002 StandoutNobel
Cytoplasmic Utilization of Human Immunodeficiency Virus Type 1 Genomic RNA Is Not Dependent on a Nuclear Interaction with Gag
2012
A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques
1998