Citation Impact
Citing Papers
The Helicobacter pylori Vacuolating Toxin Inhibits T Cell Activation by Two Independent Mechanisms
2003
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
2012 Standout
Helicobacter pylori Induces MAPK Phosphorylation and AP-1 Activation via a NOD1-Dependent Mechanism
2009
Critical contribution of 3′ non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA
2022 StandoutNobel
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
2013
Global view of human protein glycosylation pathways and functions
2020
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Hyperplastic gastric tumors induced by activated macrophages in COX‐2/mPGES‐1 transgenic mice
2004
Host-Bacterial Interactions in Helicobacter pylori Infection
2008
Helicobacter pylori Vacuolating Cytotoxin, VacA, Is Responsible for Gastric Ulceration
2004
Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas
2006
Helicobacter pylori persistence: biology and disease
2004
Mast Cells Are Critical Mediators of Vaccine-Induced Helicobacter Clearance in the Mouse Model
2005
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Helicobacter pylorivacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity
2004
Helicobacter pylori Eradication Has the Potential to Prevent Gastric Cancer: A State-of-the-Art Critique
2005
Inhibitors of Protein Tyrosine Phosphatases: Next‐Generation Drugs?
2005
Outer membrane vesicles enhance the carcinogenic potential of Helicobacter pylori
2008
Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?
2018 StandoutNobel
Synthesis of a Glycopeptide Vaccine Conjugate for Induction of Antibodies Recognizing O‐Mannosyl Glycopeptides
2014
Ribosome Footprint Profiling of Translation throughout the Genome
2016
Marine natural products
1990 Standout
Cellular Vacuolation and Mitochondrial Cytochrome c Release Are Independent Outcomes of Helicobacter pylori Vacuolating Cytotoxin Activity That Are Each Dependent on Membrane Channel Formation
2003
Effect of the flavonoid quercetin on inflammation and lipid peroxidation induced by Helicobacter pylori in gastric mucosa of guinea pig
2008
Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori
2003
Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes?
2014
Helicobacter pylori Vacuolating Cytotoxin Induces Activation of the Proapoptotic Proteins Bax and Bak, Leading to Cytochrome c Release and Cell Death, Independent of Vacuolation
2006
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
2000
The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori
2004
Helicobacter pylori in Health and Disease
2009
Global cancer transitions according to the Human Development Index (2008–2030): a population-based study
2012 Standout
Recent advances in mRNA vaccine technology
2020 StandoutNobel
Locating proteins in the cell using TargetP, SignalP and related tools
2007 Standout
Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
2019
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Multiple Oligomeric States of the Helicobacter pylori Vacuolating Toxin Demonstrated by Cryo-electron Microscopy
2002 StandoutNobel
Role of the Microbiota in Immunity and Inflammation
2014 Standout
The COG Complex, Rab6 and COPI Define a Novel Golgi Retrograde Trafficking Pathway that is Exploited by SubAB Toxin
2009
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
2016 Nature
Helicobacter pylori cag-Type IV Secretion System Facilitates Corpus Colonization to Induce Precancerous Conditions in Mongolian Gerbils
2005
N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
2018
NOD1 and NOD2 signalling links ER stress with inflammation
2016 StandoutNature
Lymphangioleiomyomatosis — a wolf in sheep’s clothing
2012
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Helicobacter pylori VacA, a paradigm for toxin multifunctionality
2005
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 Standout
Helicobacter pylori CagA Containing ITAM‐Like Sequences Localized to Lipid Rafts Negatively Regulates VacA‐Induced Signaling In Vivo
2003
Coadaptation of Helicobacter pylori and humans: ancient history, modern implications
2009
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy
2005 StandoutNobel
Paradoxical roles of the immune system during cancer development
2006 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Helicobacter pyloriInfection
2002 Standout
Survey of the year 2003 commercial optical biosensor literature
2004
Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions
2015 Standout
Helicobacter pylori: gastric cancer and beyond
2010
Targeting autophagy in cancer
2017 Standout
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
Reading, writing and erasing mRNA methylation
2019 Standout
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
1999
The PI3K Pathway in Human Disease
2017 Standout
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
2011 Standout
Recent advances in understanding the antibacterial properties of flavonoids
2011 Standout
Essential Role of a GXXXG Motif for Membrane Channel Formation by Helicobacter pylori Vacuolating Toxin
2003
Glial Nax Channels Control Lactate Signaling to Neurons for Brain [Na+] Sensing
2007
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
2006 Standout
Mast cells in the development of adaptive immune responses
2005 Standout
Functional Properties of the p33 and p55 Domains of the Helicobacter pylori Vacuolating Cytotoxin
2005
A Dominant Negative Mutant of Helicobacter pyloriVacuolating Toxin (VacA) Inhibits VacA-induced Cell Vacuolation
1999
Potential cytotoxic and amoebicide activity of first row transition metal compounds with 2,9-bis-(2′,5′-diazahexanyl)-1,1-phenanthroline (L1)
2012
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
The human microbiome: at the interface of health and disease
2012 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
The integrated stress response
2016 Standout
The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
1999
Binding of Ovarian Cancer Antigen CA125/MUC16 to Mesothelin Mediates Cell Adhesion
2004 Standout
Vanillic Acid Derivatives from the Green Algae Cladophora socialis As Potent Protein Tyrosine Phosphatase 1B Inhibitors
2007
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Inhibitoren der Proteintyrosinphosphatasen: Kandidaten für zukünftige Wirkstoffe?
2005
Helicobacter pyloriand Gastric Cancer: Factors That Modulate Disease Risk
2010
Cutting Edge: Both Activating and Inhibitory Fc Receptors Expressed on Mast Cells Regulate Experimental Allergic Encephalomyelitis Disease Severity
2003
Induction of Antibodies Directed Against Branched Core O‐Mannosyl Glycopeptides—Selectivity Complimentary to the ConA Lectin
2017
Helicobacter pylori Membrane Vesicles Stimulate Innate Pro- and Anti-Inflammatory Responses and Induce Apoptosis in Jurkat T Cells
2014
A 12-Amino-Acid Segment, Present in Type s2 but Not Type s1 Helicobacter pylori VacA Proteins, Abolishes Cytotoxin Activity and Alters Membrane Channel Formation
2001
Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism
2004
All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion
2005
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori
2016 StandoutNobel
The Helicobacter pylori vacuoloating cytotoxin: from cellular vacuolation to immunosuppressive activities
2004
Amino-Terminal Hydrophobic Region of Helicobacter pylori Vacuolating Cytotoxin (VacA) Mediates Transmembrane Protein Dimerization
2001
Fourteen-Member Macrolides Suppress Interleukin-8 Production but Do Not Promote Apoptosis of Activated Neutrophils
2002 StandoutNobel
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels
2004
Geographic Differences in Gastric Cancer Incidence Can be Explained by Differences between Helicobacter pylori Strains
2008
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer.
2003
Uptake ofHelicobacter pyloriOuter Membrane Vesicles by Gastric Epithelial Cells
2010
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Clustering and Redistribution of Late Endocytic Compartments in Response toHelicobacter pyloriVacuolating Toxin
2004
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Inhibition of primary human T cell proliferation byHelicobacter pylorivacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
2004
Helicobacter pylori cholesteryl glucosides interfere with host membrane phase and affect type IV secretion system function during infection in AGS cells
2011
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity
1998
Type V Protein Secretion Pathway: the Autotransporter Story
2004
Works of Kinnosuke Yahiro being referenced
Translation from the 5′ untranslated region shapes the integrated stress response
2016 Science
Helicobacter pylori VacA-induced Inhibition of GSK3 through the PI3K/Akt Signaling Pathway
2008
Differential Activities of Plant Polyphenols on the Binding and Internalization of Cholera Toxin in Vero Cells
2005
Inhibitory Effects of Polyphenols on Gastric Injury by Helicobacter pylori VacA Toxin
2005
Vacuolating cytotoxin purified from causes mitochondrial damage in human gastric cells
1999
Identification and characterization of receptors for vacuolating activity of subtilase cytotoxin
2006
Identification and characterization of the hemolysin glycoprotein receptor on Intestine 407 cells
1999
Subtilase cytotoxin, produced by Shiga-toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP and induces cell cycle arrest at G1 by downregulation of cyclin D1
2008
Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells
2004
Activation of Helicobacter pylori VacA Toxin by Alkaline or Acid Conditions Increases Its Binding to a 250-kDa Receptor Protein-tyrosine Phosphatase β
1999
Essential Domain of Receptor Tyrosine Phosphatase β (RPTPβ) for Interaction with Helicobacter pylori Vacuolating Cytotoxin
2004
Low-density Lipoprotein Receptor-related Protein-1 (LRP1) Mediates Autophagy and Apoptosis Caused by Helicobacter pylori VacA
2012
Morphologic Differentiation of HL-60 Cells Is Associated with Appearance of RPTPβ and Induction of Helicobacter pyloriVacA Sensitivity
2000
Relationship Between Gastric Ulcer and Helicobacter pylori VacA Detected in Gastric Juice Using Bead‐ELISA Method
2002
Protein-tyrosine Phosphatase α, RPTPα, Is a Helicobacter pylori VacA Receptor
2003
Characterization of Cholix Toxin-induced Apoptosis in HeLa Cells
2011
Inhibitory effects of various plant polyphenols on the toxicity of Staphylococcal α-toxin
2007
Helicobacter pyloriVacuolating Cytotoxin Binds to the 140-kDa Protein in Human Gastric Cancer Cell Lines, AZ-521 and AGS
1997
A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor
2019
Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin from
2001
Effects of Prolactin on TSC2 -Null Eker Rat Cells and in Pulmonary Lymphangioleiomyomatosis
2010
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
2003
Cutting Edge: VacA, a Vacuolating Cytotoxin of Helicobacter pylori, Directly Activates Mast Cells for Migration and Production of Proinflammatory Cytokines
2002
Molecular Characterization of Helicobacter pylori VacA Induction of IL-8 in U937 Cells Reveals a Prominent Role for p38MAPK in Activating Transcription Factor-2, cAMP Response Element Binding Protein, and NF-κB Activation
2008
Clustering of Helicobacter pylori VacA in Lipid Rafts, Mediated by Its Receptor, Receptor-Like Protein Tyrosine Phosphatase β, Is Required for Intoxication in AZ-521 Cells
2006