Citation Impact
Citing Papers
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template
1984
Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates
2016
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
1986
Inflammation and cancer
2002 StandoutNature
Vasculogenic Mimicry and Tumor Angiogenesis
2000
Projection structure of rhodopsin
1993 StandoutNatureNobel
Clinical translation of angiogenesis inhibitors
2002 Standout
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
Search for the optimal sequence of the ribosome binding site by random oligonucleotide-directed mutagenesis
1988
Clinical Application of Antiangiogenic Therapy: Microvessel Density, What It Does and Doesn't Tell Us
2002
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
2012
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
Tumor angiogenesis: past, present and the near future
2000
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
2005
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Structure and function of an irreversible agonist-β2 adrenoceptor complex
2011 StandoutNatureNobel
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
2000 Standout
Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors
2002
Chronic immune activation and inflammation in the pathogenesis of aids and cancer
2002
Membrane Type 1-Matrix Metalloproteinase Is Activated during Migration of Human Endothelial Cells and Modulates Endothelial Motility and Matrix Remodeling
2001
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
2003
VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis
2002
multifunctional enzymes in cancer
2006
The angiogenic switch in carcinogenesis
2009
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Immunogenicity of protein therapeutics
2007
Matrix metalloproteinases: multifunctional contributors to tumor progression
2000
The Structure and Insertion of Integral Proteins in Membranes
1990
Computationally Designed Bispecific Antibodies using Negative State Repertoires
2016
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo
2002
T cell metabolic fitness in antitumor immunity
2015
Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing
2008
An amino-bisphosphonate targets MMP-9–expressing macrophages and angiogenesis to impair cervical carcinogenesis
2004
Extracellular matrix remodelling and cellular differentiation
1999
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Tumorigenesis and the angiogenic switch
2003 Standout
Endogenous Inhibitors of Angiogenesis
2005
A model for the RNA-catalyzed replication of RNA.
1986 StandoutNobel
Growth factor–induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen
2001
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
2000 StandoutNobel
Defining the Inside and Outside of a Catalytic RNA Molecule
1989 StandoutScienceNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin.
1988
An amino-bisphosphonate targets MMP-9–expressing macrophages and angiogenesis to impair cervical carcinogenesis
2004
Angiomotin
2001
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.
1990
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region
1987 StandoutNatureNobel
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
1990 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.
2000 StandoutNobel
A new cell division operon inEscherichia coli
1986
Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase
1990 StandoutScience
Ku is associated with the telomere in mammals
1999 StandoutNobel
Effect of Carboxylic Acid Side Chains on the Absorption Maximum of Visual Pigments
1989 Science
Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer
2009
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-rasoncogene
1986
The recognition by RNase P of precursor tRNAs.
1988 StandoutNobel
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
2000
Human Cells Contain a DNA-Activated Protein Kinase that Phosphorylates Simian Virus 40 T Antigen, Mouse p53, and the Human Ku Autoantigen
1990
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based onPseudomonasexotoxin A
2012
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
2003
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
2006
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.
1993
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Angiogenesis
2006
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
TUMOR STROMA AND REGULATION OF CANCER DEVELOPMENT
2006
Imaging the glycome
2008 StandoutNobel
Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease
2015
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena.
1987 StandoutNobel
Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
1985 StandoutNobel
Iron−Sulfur Cluster Biosynthesis: Toward an Understanding of Cellular Machinery and Molecular Mechanism
2004
Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis
2002 Science
A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells
2005
Angiogenesis in Endocrine Tumors
2003
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Nudeotide sequence of the BsuRI restriction-modification system
1985 StandoutNobel
Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor
1986 StandoutNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Monomeric Fc Fusions
2006
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Rhodopsin Mutants That Bind But Fail to Activate Transducin
1990 Science
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
The high affinity state of the beta 2-adrenergic receptor requires unique interaction between conserved and non-conserved extracellular loop cysteines.
1994
A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy
2005
Works of Kin-Ming Lo being referenced
A Low-Toxicity IL-2–Based Immunocytokine Retains Antitumor Activity Despite Its High Degree of IL-2 Receptor Selectivity
2011
The Development of a Modified Human IFN-α2b Linked to the Fc Portion of Human IgG1 as a Novel Potential Therapeutic for the Treatment of Hepatitis C Virus Infection
2004
SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies†
2010
Bi-functional cytokine fusion proteins for gene therapy and antibody-targeted treatment of cancer
2002
Effect of Antiangiogenic Therapy on Slowly Growing, Poorly Vascularized Tumors in Mice
2001
Activation of Ha-ras p21 by Substitution, Deletion, and Insertion Mutations
1985
Zinc-dependent dimers observed in crystals of human endostatin
1998
An anti-CD20–IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma
2005
Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons
1984
Oligomerization-Dependent Regulation of Motility and Morphogenesis by the Collagen Xviii Nc1/Endostatin Domain
2001
Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice
1999 Science
Studies on the Light-transducing Pigment Bacteriorhodopsin
1983
Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T Cells in Tumors from Mice and Humans
2014