Citation Impact
Citing Papers
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
NMR diffusion measurements to characterise membrane transport and solute binding
1997
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
1,3-dialkylxanthine derivatives having high potency as antagonists at human A2B adenosine receptors
1999
Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein
1994
Muscle-derived positive and negative regulators of the immune response
2005
Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4
1994 StandoutNatureNobel
Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
2013 StandoutNature
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
The Diversity of Volume Regulatory Mechanisms
1998
Stomatin: a putative cation transport regulator in the red cell membrane
1993
Continuous measurement of cell volume changes in perfused rat salivary glands by proton NMR
1994
Friedel–Crafts‐Type Mechanism for the Enzymatic Elimination of Ammonia from Histidine and Phenylalanine
2005
Physiology of Cell Volume Regulation in Vertebrates
2009
Volume-sensitive Chloride Channel Activity Does Not Depend on Endogenous P-glycoprotein
1995
Unitary anion currents through phospholemman channel molecules
1995 Nature
Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms
2004
[17] Mechanisms of inhibition of DNA polymerases by 2′-deoxyribonucleoside 5′-triphosphate analogs
1995
19F NMR studies of changes in membrane potential and intracellular volume during dexamethasone‐induced apoptosis in human leukemic cell lines
1993
CpG motifs in bacterial DNA trigger direct B-cell activation
1995 StandoutNature
Taurine efflux and the regulation of cell volume in incubated slices of rat cerebral cortex
1994
Angiotensin II induces TIMP-1 production in rat heart endothelial cells
1996
Effects of extracellular bicarbonate ions and pH on volume-regulatory taurine efflux from rat cerebral cortical slices in vitro: evidence for separate neutral and anionic transport mechanisms
1994
Membrane Mechanisms and Intracellular Signalling in Cell Volume Regulation
1995
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
1997 StandoutNobel
Cell volume regulated transporters of compatible osmolytes
1995
In vivo31P NMR study of early cellular responses to hyperosmotic shock in cultured glioma cells
1992
Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling
1991
Circadian Regulation of cAMP Response Element-mediated Gene Expression in the Suprachiasmatic Nuclei
1999
Adenosine analogs with covalently attached lipids have enhanced potency at A1‐adenosine receptors
1987
Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations
2002
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
1994 StandoutNature
Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?
1993 Science
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Antisense oligodeoxynucleotide to the cystic fibrosis transmembrane conductance regulator inhibits cyclic AMP-activated but not calcium-activated cell volume reduction in a human pancreatic duct cell line.
1993
Maintenance of cell volume in the central nervous system
1993
Single-Channel Properties of Volume-Sensitive Cl− Channel in ClC-3–Deficient Cardiomyocytes
2005
Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation
1999
Mechanical stimuli induce intracellular calcium response in a subpopulation of cultured rat sensory neurons
1999
Prolegomena to Future Experimental Efforts on Genetic Code Engineering by Expanding Its Amino Acid Repertoire
2004
DCPIB is a novel selective blocker of ICl,swell and prevents swelling‐induced shortening of guinea‐pig atrial action potential duration
2001
Single channel properties of a volume sensitive anion channel: Lessons from noise analysis
1996
CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship
1993 Nature
Mechanism‐Inspired Engineering of Phenylalanine Aminomutase for Enhanced β‐Regioselective Asymmetric Amination of Cinnamates
2011 StandoutNobel
Structure and pharmacology of the proton-ATPases
1991
Memory of Extracellular Adenosine A2A Purinergic Receptor-mediated Signaling in Murine T Cells
1997 StandoutNobel
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.
1993
Pathophysiology and puzzles of the volume‐sensitive outwardly rectifying anion channel
2009
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
2005 StandoutNobel
Thousands of chemical starting points for antimalarial lead identification
2010 Nature
Cell-permeable fluorescent indicator for cytosolic chloride
1991
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential
1992
Intracellular Volume Measurement and Detection of Edema: Multinuclear NMR Studies of Intact Rat Hearts during Normothermic Ischemia
1995
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) ? a selective high affinity antagonist radioligand for A1 adenosine receptors
1987
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance
2000 Standout
Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells
1994
Phosphate-enhanced transfection of cationic lipid-complexed mRNA and plasmid DNA
1998 StandoutNobel
Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor
2002 StandoutNobel
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
2002 StandoutNatureNobel
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
1990 Nature
Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors
1996
A mouse model for the delta F508 allele of cystic fibrosis.
1995 StandoutNobel
Amazing chloride channels: an overview
2003
Differential expression of volume‐regulated anion channels during cell cycle progression of human cervical cancer cells
2000
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Swelling-activated organic osmolyte efflux: A new role for anion channels
1995
Volume-activated Cl− channels
1996
PDF and cAMP enhance PER stability in Drosophila clock neurons
2014 StandoutNobel
Synthesis of the calothrixins, pentacyclic indolo[3,2-j]phenanthridine alkaloids, using a biomimetic approach
2007
Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor
1997
Adjustable Receptor Based on a [3]Rotaxane Whose Two Threaded Rings Are Rigidly Attached to Two Porphyrinic Plates: Synthesis and Complexation Studies
2009 StandoutNobel
Potential of Transfected Muscle Cells to Contribute to DNA Vaccine Immunogenicity
2007
Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology
2017
Friedel−Crafts Acylation and Metalation Strategies in the Synthesis of Calothrixins A and B
2003
Anion Transport in Heart
2000
Free amino compounds and cell volume regulation in erythrocytes from different marine fish species under hypoosmotic conditions: the role of a taurine channel
1994
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.
1996
Synthesis, Electrochemistry, and Bioactivity of the Cyanobacterial Calothrixins and Related Quinones
2004
Scalable and Highly Diastereo- and Enantioselective Catalytic Diels–Alder Reaction of α,β-Unsaturated Methyl Esters
2018 StandoutNobel
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
A biomimetic synthesis of the indolo[3,2-j]phenanthridine alkaloid, calothrixin B
2006
Enzymatische Eliminierung von Ammoniak aus Histidin und Phenylalanin: der Friedel‐Crafts‐ähnliche Mechanismus
2005
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Application of the aza-Diels–Alder reaction in the synthesis of natural products
2017
Human cancer cell (Jurkat) killing by the cyanobacterial metabolite calothrixin A
2003
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.
1993
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Progress towards the Total Synthesis of the Bioactive Calothrixins A and B
2009
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.
1995 Standout
Multi-State Regulation of the Dihydrogen Phosphate Binding Affinity to a Light- and Heat-Responsive Bis-Urea Receptor
2014 StandoutNobel
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Functional Coherence of the Human Y Chromosome
1997 StandoutScience
Cyclic AMP prevents activation of a swelling‐induced chloride‐sensitive conductance in chick heart cells.
1995
Molecular Structure and Physiological Function of Chloride Channels
2002
Osmoregulated taurine transport in H4IIE hepatoma cells and perfused rat liver
1997
Ion permeation and selectivity in ClC-type chloride channels
2001
Volume regulatory taurine release in human tracheal 9HTEo- and multidrug resistant 9HTEo-/Dx cells
1996
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids
2006 StandoutNobel
Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine
2002 StandoutNobel
The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding
1994
Concise and Efficient Synthesis of Calothrixin B
2006
Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel
1998
Some Metabolic Aspects of Fluoroacetate Especially Related to Fluorocitrate
1972
A new total synthesis of an indolo[3,2-j]phenanthridine alkaloid calothrixin B
2005
Extracellular ATP stimulates volume decrease inNecturusred blood cells
1999
Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux
1993
Synthesis of the Potent Antimalarials Calothrixin A and B
2000
A simple and concise route to calothrixin B
2002
Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine
2002 StandoutNobel
A New Radical-Based Route to Calothrixin B
2006
Genetic interactions affecting touch sensitivity in Caenorhabditis elegans.
1996 StandoutNobel
Association of the Band 3 Protein with a Volume-Activated, Anion and Amino Acid Channel: A Molecular Approach
1997
A biomimetic synthesis of calothrixin B
2006
A one pot synthesis of annulated carbazole analogs
2008
Cystic fibrosis: a disease in electrolyte transport
1990
Expression of band 3 anion exchanger induces chloride current and taurine transport: structure-function analysis.
1995
The biochemical defect in cystic fibrosis.
1992
Calothrixins, a New Class of Human DNA Topoisomerase I Poisons
2009
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Prolegomena zum experimentellen Engineering des genetischen Codes durch Erweiterung seines Aminosäurerepertoires
2004
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Adenosine receptors: Clinical implications and biochemical mechanisms
1988
A Versatile Synthesis of Annulated Carbazole Analogs Involving a Domino Reaction of Bromomethylindoles with Arenes/Heteroarenes
2008
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Concise Total Synthesis of Calothrixins A and B
2011
Biokatalyse mit nicht‐natürlichen Aminosäuren: Enzymologie trifft Xenobiologie
2017
Aquaporins in Saccharomyces : Characterization of a second functional water channel protein
2001 StandoutNobel
Transient up-regulation of P2Y2nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
1997 StandoutNobel
Impaired cell volume regulation in intestinal crypt epithelia of cystic fibrosis mice.
1995 StandoutNobel
Synthetic Studies on Indolocarbazoles: Total Synthesis of Staurosporine Aglycon
2011
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
2001 StandoutNobel
Intermolecular Atom Transfer Radical Addition to Olefins Mediated by Oxidative Quenching of Photoredox Catalysts
2011
Cutting Long Syntheses Short: Access to Non‐Natural Tyrosine Derivatives Employing an Engineered Tyrosine Phenol Lyase
2010
Total Synthesis of Bioactive Indolo[3,2-j]phenanthridine Alkaloid, Calothrixin B
2010
Cation flux studies of the lesion induced in human erythrocyte membranes by the thermostable direct hemolysin of Vibrio parahaemolyticus
1993
Cell volume and drug action: Some interactions and perspectives
1995
Works of Kiaran Kirk being referenced
A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.
1986
Nitrendipine is a potent inhibitor of the Ca2+‐activated K+ channel of human erythrocytes
1992
Incorporation of 2-fluorohistidine in murine protein
1992
Volume‐regulatory taurine release from a human lung cancer cell line
1993
NMR methods for measuring membrane transport rates
1990
Anion-selectivity of the Swelling-activated Osmolyte Channel in Eel Erythrocytes
1996
Further investigation of the use of dimethyl methylphosphonate as a 31P-NMR probe of red cell volume
1988
Hypophosphite ion as a 31P nuclear magnetic resonance probe of membrane potential in erythrocyte suspensions
1988
Novel Anion Dependence of Induced Cation Transport in Malaria-infected Erythrocytes
1995
Characterization of transmembrane chemical shift differences in the phosphorus-31 NMR spectra of various phosphoryl compounds added to erythrocyte suspensions
1988
The Role of P2Y1 Purinergic Receptors and Cytosolic Ca2+ in Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line
2002
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
2000 Nature
Efficiency of plasmid delivery and expression after lipid-mediated gene transfer to human cells in vitro.
1996
Chemistry and pharmacology of ring-fluorinated catecholamines
1995
Swelling-induced chloride currents in neuroblastoma cells are calcium dependent
1995
Anion channel blockers inhibit swelling-activated anion, cation, and nonelectrolyte transport in HeLa cells
1996
Antisense oligodeoxynucleotide to the cystic fibrosis gene inhibits anion transport in normal cultured sweat duct cells.
1991
In search of a selective inhibitor of the induced transport of small solutes in Plasmodium falciparum-infected erythrocytes: effects of arylaminobenzoates
1995
Fluorocitric acid: selective microbial degradation of the inhibitory isomer
1970
Red cell volume changes monitored using a new 31P NMR procedure
1985
Zwitterionic and Anionic Forms of a Serotonin Analog as Transport Substrates
1989
Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel.
1994
Osmotic Swelling Activates two Pathways for K<sup>+</sup> Efflux in a Rat Hepatoma Cell Line
2004
Synthesis of a difluoromethylenephosphonate analogue of AZT 5'-triphosphate and its inhibition of HIV-1 reverse transcriptase
1991
Transport of organic substrates via a volume-activated channel.
1992
ChemInform Abstract: Fluorinated Amino Acids in Nerve Systems
1997
[3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.
1986
Swelling-activated Organic Osmolyte Channels
1997
An enzymatic synthesis of 2-azido-L-tyrosine
1992
Triethyl phosphate as an internal 31P NMR reference in biological samples
1986
The contribution of magnetic susceptibility effects to transmembrane chemical shift differences in the 31P NMR spectra of oxygenated erythrocyte suspensions.
1988
FUNCTIONAL PROPERTIES AND PHYSIOLOGICAL ROLES OF ORGANIC SOLUTE CHANNELS
1998
Transfection of wild-type CFTR into cystic fibrosis lymphocytes restores chloride conductance at G1 of the cell cycle.
1992
In vitro and in vivo studies of the effects of halogenated histidine analogs on Plasmodium falciparum
1988
Cl- permeability of human sweat duct cells monitored with fluorescence-digital imaging microscopy: evidence for reduced plasma membrane Cl- permeability in cystic fibrosis.
1989
Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology.
1994
Swelling-activated K+ transport via two functionally distinct pathways in eel erythrocytes
1996
Two pathways for choline transport in eel erythrocytes: a saturable carrier and a volume-activated channel
1994
Enhanced choline and Rb+ transport in human erythrocytes infected with the malaria parasite Plasmodium falciparum
1991
A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli
1998
Histidine ammonia-lyase. The use of 4-fluorohistidine in identification of the rate-determining step.
1975
Calothrixins A and B, novel pentacyclic metabolites from Calothrix cyanobacteria with potent activity against malaria parasites and human cancer cells
1999
Inhibition of volume-activated I- and taurine efflux from HeLa cells by P-glycoprotein blockers correlates with calmodulin inhibition.
1994