Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions
2013 StandoutNobel
Oxidative Stress
2017 Standout
Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
2015
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma
2014
Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma
2012
Current State of Preeclampsia Mouse Models: Approaches, Relevance, and Standardization
2021
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
DNA targeting specificity of RNA-guided Cas9 nucleases
2013 Standout
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
2012
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
2013
CpG islands and the regulation of transcription
2011 Standout
The Discovery of 5‐Formylcytosine in Embryonic Stem Cell DNA
2011
Mouse ooplasm confers context-specific reprogramming capacity
2012
Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells
2013
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
2014 Standout
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
A unique regulatory phase of DNA methylation in the early mammalian embryo
2012 Nature
Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development
2011
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells
2011
Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?
2011 StandoutNobel
DNA methylation: roles in mammalian development
2013 Standout
Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development
2013
The maternal to zygotic transition in mammals
2013
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
2013 Standout
Short-term memory of danger signals and environmental stimuli in immune cells
2013
Hydroxylation mediates chromatin demethylation
2012
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
2011
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development
2011
Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome
2012
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
2011
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming
2013
Genome engineering using the CRISPR-Cas9 system
2013 Standout
Alzheimer's disease
2006 Standout
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Contribution of Intragenic DNA Methylation in Mouse Gametic DNA Methylomes to Establish Oocyte-Specific Heritable Marks
2012
Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
2013
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Parallel mechanisms of epigenetic reprogramming in the germline
2012
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
2011 Nature
Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids
2012
Alzheimer's Disease
2010 Standout
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
2012 Nature
Chromatin dynamics during cellular reprogramming
2013 Nature
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy
2015
Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
2012 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Transcription factor networks in trophoblast development
2022
Active DNA demethylation by Gadd45 and DNA repair
2012
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
GSK-3: Functional Insights from Cell Biology and Animal Models
2011
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
Tau pathology in Alzheimer disease and other tauopathies
2004
DNA Demethylation Dynamics
2011
Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming
2013
Recognition of 5-Hydroxymethylcytosine by the Uhrf1 SRA Domain
2011
De novo DNA methylation: a germ cell perspective
2011
Development and Maintenance of Regulatory T cells
2013 StandoutNobel
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
2011
Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo
2012
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Mapping recently identified nucleotide variants in the genome and transcriptome
2012
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
The application of targeted mass spectrometry‐based strategies to the detection and localization of post‐translational modifications
2014
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
The Curious Chemical Biology of Cytosine: Deamination, Methylation,and Oxidation as Modulators of Genomic Potential
2011
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies
2008
Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos
2011 Science
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
2011
PLA2G6 guards placental trophoblasts against ferroptotic injury
2020
Distinct roles for TET family proteins in regulating human erythropoiesis
2017
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Efficient TALEN-mediated gene knockout in livestock
2012
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
Aberrant Activation of Focal Adhesion Proteins Mediates Fibrillar Amyloid β-Induced Neuronal Dystrophy
2003
Chemical Glycoproteomics
2016 StandoutNobel
Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine
2012 Science
Works of Khursheed Iqbal being referenced
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
2011
ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development
2021
Inhibition of Neurofibrillary Degeneration: A Promising Approach to Alzheimers Disease and Other Tauopathies
2004
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
2011 Nature
Cytoplasmic Injection of Circular Plasmids Allows Targeted Expression in Mammalian Embryos
2009
Hemochorial placentation: development, function, and adaptations†
2018
Post-translational modifications of tau protein.
2006
Hypoxia and Placental Development
2017
535 Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5
1996