Citation Impact
Citing Papers
Chromosomal Instability Confers Intrinsic Multidrug Resistance
2011
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Morphology of sporadic colorectal cancer with DNA replication errors
1998
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
2000
GENOMIC INSTABILITY IN COLORECTAL CARCINOMAS: COMPARISON OF DIFFERENT EVALUATION METHODS AND THEIR BIOLOGICAL SIGNIFICANCE
1996
BRCA1 and BRCA2: 1994 and beyond
2004
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
1995
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc‐binding domains
1995
Apoptosis in cancer therapy: Crossing the threshold
1994
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
1998
Akt-regulated pathways in prostate cancer
2005
Genetic instabilities in human cancers
1998 StandoutNature
Haplotype Sharing Analysis Using Mantel Statistics
2005
Molecular Predictors of Survival after Adjuvant Chemotherapy for Colon Cancer
2001
Genetic pathways in colorectal and other cancers
1999
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Breast and Ovarian Cancer
2003
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1996 StandoutNature
Microsatellite Instability and 8p Allelic Imbalance in Stage B2 and C Colorectal Cancers
1999
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Activation of a Cryptic Splice Site of PTEN and Loss of Heterozygosity in Benign Skin Lesions in Cowden Disease
2001
PTEN: One Gene, Many Syndromes
2003
Loss of Expression of the PTEN Gene Protein Product Is Associated with Poor Outcome in Breast Cancer
2001
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
2007 Standout
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
2001
Breast Cancer after Prophylactic Bilateral Mastectomy in Women with aBRCA1orBRCA2Mutation
2001
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Mouse models for colorectal cancer
1999
The Molecular Basis of Turcot's Syndrome
1995
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer
2000
The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis
1994
Sunburn and p53 in the onset of skin cancer
1994 StandoutNature
Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer
1997
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
2000
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Modifiers of risk of hereditary breast and ovarian cancer
2002
Genetic instability in colorectal cancers
1997 StandoutNature
Genetic alterations in breast cancer
1995
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
1994
Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Hereditary Colorectal Cancer
2003 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers
2001
Mutations of the human PTEN gene
2000
Determination of microsatellite instability,p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: Relationship with response to 5-fluorouracil and survival
2001
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Oral Contraceptives and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers
2002
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
A functionally inactive p53 protein interatocarcinoma cells is activated by either DNA damage or cellular differentiation
1996
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
1993 Standout
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Prognostic Significance of DNA Replication Errors in Young Patients With Colorectal Cancer
1998
DNA mismatch repair and cancer
2001
Meiotic Pachytene Arrest in MLH1-Deficient Mice
1996
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines
1997
DNA Mismatch Repair-dependent Response to Fluoropyrimidine-generated Damage
2004
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
High Prevalence of Activated Intraepithelial Cytotoxic T Lymphocytes and Increased Neoplastic Cell Apoptosis in Colorectal Carcinomas with Microsatellite Instability
1999
Outcome of Preventive Surgery and Screening for Breast and Ovarian Cancer in BRCA Mutation Carriers
2002
ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer
2006
Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer
2003
Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers
2004
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
2002
Outcome of Preventive Surgery and Screening for Breast and Ovarian Cancer in BRCA Mutation Carriers
2002
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.
1994
Microsatellite instability: marker of a mutator phenotype in cancer.
1994
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
2001 Standout
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
1994 StandoutScience
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
DNA Loop Repair by Human Cell Extracts
1994 Science
Requirement of the Yeast RTH1 5′ to 3′ Exonuclease for the Stability of Simple Repetitive DNA
1995 Science
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Low-level microsatellite instability in most colorectal carcinomas.
2002
Cancer Cell Cycles
1996 StandoutScience
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Histopathological Identification of Colon Cancer with Microsatellite Instability
2001
MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast
1994 Science
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
1999
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Mechanisms of Estrogen Action
2001 Standout
Cost-Effectiveness of Microsatellite Instability Screening as a Method for Detecting Hereditary Nonpolyposis Colorectal Cancer
2001
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.
2003
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study
2005 Standout
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.
1998
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
2005
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
2000
PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma.
1998
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
1998 Standout
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.
1994
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group
2005 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
S100-Beta, Melanoma-Inhibiting Activity, and Lactate Dehydrogenase Discriminate Progressive From Nonprogressive American Joint Committee on Cancer Stage IV Melanoma
1999
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Ketil Heimdal being referenced
Prognostic significance of TP53 alterations in breast carcinoma
1993
Inherited Mutations in PTEN That Are Associated with Breast Cancer, Cowden Disease, and Juvenile Polyposis
1997
A BRCA1 founder mutation, identified with haplotype analysis, allowing genotype/phenotype determination and predictive testing
1997
Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study
2000
Regression analyses of prognostic factors in metastatic malignant melanoma
1989
No germline TP53 mutations detected in familial and bilateral testicular cancer
1993
Survival in prospectively ascertained familial breast cancer: Analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy
2002
Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.
1993
Oestrogen receptor (ESR) polymorphisms and breast cancer susceptibility
1994