Citation Impact
Citing Papers
The HER-2 Receptor and Breast Cancer: Ten Years of Targeted Anti–HER-2 Therapy and Personalized Medicine
2009
Fibroblast Growth Factor Receptor 1–Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival
2009
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Characterization of the Recurrent 8p11-12 Amplicon Identifies PPAPDC1B, a Phosphatase Protein, as a New Therapeutic Target in Breast Cancer
2008
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer
2012 Standout
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Prognostic significance of equivocal human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer: A cohort study
2016
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation
2017 Standout
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
Implications of the Updated 2013 American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations on Human Epidermal Growth Factor Receptor 2 Gene Testing Using Immunohistochemistry and Fluorescence In Situ Hybridization for Breast Cancer
2016
HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity
2013
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013
The clinical relevance of micropapillary carcinoma of the breast: a case–control study
2013
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
2010 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
HER2Gene Amplification in Breast Cancer
2012
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013 Standout
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
2015
Updated 2013 College of American Pathologists/American Society of Clinical Oncology (CAP/ASCO) guideline recommendations for human epidermal growth factor receptor 2 (HER2) fluorescent in situ hybridization (FISH) testing increase HER2 positive and HER2 equivocal breast cancer cases; retrospective study of HER2 FISH results of 836 invasive breast cancers
2016
Accuracy and Reproducibility of HER2 Status in Breast Cancer Using Immunohistochemistry: A Quality Control Study in Tuscany Evaluating the Impact of Updated 2013 ASCO/CAP Recommendations
2014
Triple-Negative Breast Cancer
2010 Standout
Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity
2010
Determining True HER2 Gene Status in Breast Cancers With Polysomy by Using Alternative Chromosome 17 Reference Genes: Implications for Anti-HER2 Targeted Therapy
2011
Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update
2018 Standout
The molecular underpinning of lobular histological growth pattern: a genome‐wide transcriptomic analysis of invasive lobular carcinomas and grade‐ and molecular subtype‐matched invasive ductal carcinomas of no special type
2009
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
2009
A view on drug resistance in cancer
2019 StandoutNature
Genetic effects on gene expression across human tissues
2017 StandoutNature
Understanding the language of Lys36 methylation at histone H3
2012
BRCAness revisited
2016
Transformation of Different Human Breast Epithelial Cell Types Leads to Distinct Tumor Phenotypes
2007
Integrating liquid biopsies into the management of cancer
2017
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Tumor heterogeneity: Causes and consequences
2009
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Role of tRNA modifications in human diseases
2014
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Pooled screening for antiproliferative inhibitors of protein-protein interactions
2016
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Advances in the treatment of advanced oestrogen-receptor-positive breast cancer
2016
The Clinical Utility of Biomarkers in the Management of Pancreatic Adenocarcinoma
2014
The role of regulatory variation in complex traits and disease
2015
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
2009
An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries
2017
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Histological and molecular types of breast cancer: is there a unifying taxonomy?
2009
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Highly parallel genomic assays
2006
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The Mammalian Epigenome
2007 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Impact of whole genome amplification on analysis of copy number variants
2008
Metastasis suppressors in breast cancers: mechanistic insights and clinical potential
2013
Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma
2014
‘Non-classical’ HER2 FISH results in breast cancer: a multi-institutional study
2016
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
2015 Nature
Comparison of Pathvysion and Poseidon HER2 FISH assays in measuring HER2 amplification in breast cancer: a validation study
2009
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Emerging Biological Principles of Metastasis
2017 Standout
The DNA damage response and cancer therapy
2012 Nature
EMT: 2016
2016 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor‐derived extracellular vesicles
2018
Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer
2008
A census of amplified and overexpressed human cancer genes
2009
Resistance to therapy caused by intragenic deletion in BRCA2
2008 Nature
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
2007
Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
2011 Standout
Synthetic lethality and cancer
2017
The Hallmarks of Aging
2013 Standout
Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
2009
The PI3K Pathway in Human Disease
2017 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Drugging the undruggable RAS: Mission Possible?
2014
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
2010
Emerging targeted agents in metastatic breast cancer
2013
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
2013
EXPERIMENTAL EVALUATION OF POTENTIAL ANTICANCER AGENTS. XIII. ON THE CRITERIA AND KINETICS ASSOCIATED WITH "CURABILITY" OF EXPERIMENTAL LEUKEMIA.
1964
Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action
2016
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
O-linked mucin-type glycosylation in breast cancer
2018
Galectin-Binding O-Glycosylations as Regulators of Malignancy
2015
A Bioinformatician's Guide to Metagenomics
2008
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
2017
Hunting Viral Receptors Using Haploid Cells
2015
The New Equivocal
2015
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
2009
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Functional genomics of lipid metabolism in the oleaginous yeast Rhodosporidium toruloides
2018
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
2012
Cancer Genome Landscapes
2013 StandoutScience
Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer
2021 Standout
Design and Analysis of Bar-seq Experiments
2013
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
HER2 and Chromosome 17 Effect on Patient Outcome in the N9831 Adjuvant Trastuzumab Trial
2010
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer
2020
Disease-Free Survival According to Degree of HER2 Amplification for Patients Treated With Adjuvant Chemotherapy With or Without 1 Year of Trastuzumab: The HERA Trial
2009
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Performance of Chromogenic In Situ Hybridization on Testing HER2 Status in Breast Carcinomas With Chromosome 17 Polysomy and Equivocal (2+) HercepTest Results
2009
Impact of the 2013 A merican S ociety of C linical O ncology/C ollege of A merican P athologists guideline recommendations for human epidermal growth factor receptor 2 (HER 2) testing of invasive breast carcinoma: a focus on tumours assessed as ‘equivocal’ for HER 2 gene amplification by fluorescence in‐situ hybridization
2015
Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder Cancer
2009
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
Works of Kerry Fenwick being referenced
Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity
2013
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas
2006
An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor
2014
The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial
2018
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray‐based CGH analysis
2009
Genome‐wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c‐Kit, CD117) and oestrogen receptor‐α (ERα) in response to therapeutic radiation
2009
Mixed micropapillary–ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components
2009
Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA
2005
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
2008
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C
2014
Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach
2015
Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy
2006
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease
2014
Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity
2005
Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation
2006
Genomic profile of a secretory breast cancer with an ETV6–NTRK3 duplication
2009
Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells
2017
Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer
2011
A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines
2009
Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data
2006
A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity
2013
Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas
2008
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas
2009
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast
2008
Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor
2012
The genomic profile of HER2‐amplified breast cancers: the influence of ER status
2008
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing
2011
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
2012
Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen
2011
Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma
2012
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
2015