Citation Impact
Citing Papers
Modulation of NMDA Receptor- Dependent Calcium Influx and Gene Expression Through EphB Receptors
2002 Science
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Involvement of pp60c-src with two major signaling pathways in human breast cancer.
1994
erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells
1987 Science
p185HER2 Monoclonal Antibody Has Antiproliferative Effects In Vitro and Sensitizes Human Breast Tumor Cells to Tumor Necrosis Factor
1989
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
1986
Regulation of phosphorylation of the c-erbB-2/HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells.
1991
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
1992
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain
1990 Nature
TCR zeta chain lacking exon 7 in two patients with systemic lupus erythematosus
1998
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Expression and characterization of the cystic fibrosis transmembrane conductance regulator
1990 Nature
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Primary structure of the brain alpha-spectrin [published erratum appears in J Cell Biol 1989 Mar;108(3):following 1175]
1989
A Conserved RhoGAP Limits M Phase Contractility and Coordinates with Microtubule Asters to Confine RhoA during Cytokinesis
2013
Sequence similarity of phospholipase C with the non-catalytic region of src
1988 Nature
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Association between the PDGF receptor and members of the src family of tyrosine kinases
1990
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Identification of genes expressed in C. elegans touch receptor neurons
2002 StandoutNatureNobel
Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase
1991
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
MINIREVIEW: Interactions Among a Subfamily of Nuclear Hormone Receptors: The Regulatory Zipper Model
1990
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
1987
Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA
1987
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast
1989 StandoutNatureNobel
Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor
1997 StandoutNatureNobel
Oncogenes and signal transduction
1991 Standout
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
1990 Standout
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
1988
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
1990
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain
1992
Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
2008
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Lyn and Fgr Protein-tyrosine Kinases Prevent Apoptosis during Retinoic Acid-induced Granulocytic Differentiation of HL-60 Cells
1996 StandoutNobel
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2
1994 StandoutNatureNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN
1993
SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
1991 StandoutScience
Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability
1990
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Regulation of pp60c-src and its interaction with polyomavirus middle T antigen in insect cells
1990
Characterization of pp85, a target of oncogenes and growth factor receptors.
1990
AMPLIFICATION OF c-erbB-2 ONCOGENE IN HUMAN ADENOCARCINOMAS IN VIVO
1986
Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes
1989 Science
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells.
1987
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
The Action of Oncogenes in the Cytoplasm and Nucleus
1985 Science
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation
1987
Cancer Markers of the 1990s: Comparison of the New Generation of Markers Defined by Monoclonal Antibodies and Oncogene Probes to Prototypic Markers
1990
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
The neu Gene: an erb B-Homologous Gene Distinct from and Unlinked to the Gene Encoding the EGF Receptor
1985 Science
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene.
1988
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Association of Multiple Copies of the N-mycOncogene with Rapid Progression of Neuroblastomas
1985 Standout
Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.
1989
Structural elements that regulate pp59c-fyn catalytic activity, transforming potential, and ability to associate with polyomavirus middle-T antigen
1991
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.
1988
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
Developmental regulation of c-myb in normal myeloid progenitor cells.
1985
Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma
1985 Science
EGF Receptor and erb B-2 Tyrosine Kinase Domains Confer Cell Specificity for Mitogenic Signaling
1990 Science
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck).
1988
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
1987
Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3.
1991
Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas.
1986
Features of the pp60v-src Carboxyl Terminus That Are Required for Transformation
1986
Gene Amplification of c- myc and N- myc in Small Cell Carcinoma of the Lung
1986 Science
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
1986 Nature
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.
1990
Activated Expression of the N- myc Gene in Human Neuroblastomas and Related Tumors
1984 Science
Human c-ros-1 Gene Homologous to the v-ros Sequence of UR2 Sarcoma Virus Encodes for a Transmembrane Receptorlike Molecule
1986
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins
1993 StandoutScienceNobel
Epidermal-Growth-Factor-Dependent Transformation by a Human EGF Receptor Proto-Oncogene
1987 Science
Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants
1987 StandoutNobel
A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity
1990
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.
1986
The neu oncogene encodes an epidermal growth factor receptor-related protein
1986 Nature
Isolation and Oncogenic Potential of a Novel Human src-Like Gene
1986
Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.
1987
Growth Factors and Cancer
1991 StandoutScience
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor.
1996 StandoutNobel
Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.
1990
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.
1987
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
1984 StandoutNature
Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases.
1987
Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro
1985
The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-rafcarrying retrovirus
1987
A thousand and one protein kinases
1987
p145, a Protein with Associated Tyrosine Kinase Activity in a Human Gastric Carcinoma Cell Line
1988
The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development.
1994
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.
1989
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor
1985
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.
1988
Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen
1990
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
1986
Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells
1989 StandoutScienceNobel
Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.
1987 StandoutNobel
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
1985 Nature
Oncogene Amplification in Tumor Cells
1986
A Novel Putative Tyrosine Kinase Receptor Encoded by the eph Gene
1987 Science
c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles.
1985
Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts.
1988
Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers
1990 Science
Identification and characterization of p59fyn (a src-like protein tyrosine kinase) in normal and polyoma virus transformed cells.
1988
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.
1987
A distinctive family of embryonic protein-tyrosine kinase receptors.
1990
A Novel Human Gene Closely Related to the abl Proto-Oncogene
1986 Science
A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner
1989
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus.
1988
Additional member of the protein-tyrosine kinase family: the src- and lck-related protooncogene c-tkl.
1987
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia
1992 StandoutScienceNobel
Works of Kentaro Semba being referenced
Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis
2003
Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3β-mediated phosphorylation of β-catenin
2007
Characterization of Fyn-mediated Tyrosine Phosphorylation Sites on GluRε2 (NR2B) Subunit of the N-Methyl-d-aspartate Receptor
2001
Temporal Perturbation of Tyrosine Phosphoproteome Dynamics Reveals the System-wide Regulatory Networks
2008
An in vivo screening system to identify tumorigenic genes
2016
Identification of two novel members oferbAsuperfamily by molecular cloning: the gene products of the two are highly related to each other
1988
Amplification and Enhanced Expression of the Epidermal Growth Factor Receptor Gene in A431 Human Carcinoma Cells
1984 Science
Location of the c- yes Gene on the Human Chromosome and Its Expression in Various Tissues
1985 Science
Structure, expression, and chromosomal location of the human c-fgr gene.
1986
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.
1985
The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.
1987
yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.
1986
Characterization of cDNA Clones for the Human c-yes Gene
1987
Functional and physical interaction of protein-tyrosine kinases Fyn and Csk in the T-cell signaling system.
1993
The yes-Related Cellular Gene lyn Encodes a Possible Tyrosine Kinase Similar to p56lck
1987
Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus.
1988
A v-erbB-related protooncogene, c-erb-B-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma
1985
Overexpression of src family gene for tyrosine-kinase p59fyn in CD4-CD8- T cells of mice with a lymphoproliferative disorder.
1989
Structure, Expression, and Chromosomal Location of the Human c-fgr Gene
1986
Transformation of Chicken Embryo Fibroblast Cells by Avian Retroviruses Containing the Human Fyn Gene and Its Mutated Genes
1990
Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.
1986
Characterization of cDNA clones for the human c-yes gene.
1987
In vitro transcription of infectious RNAs from full-length cDNAs of tobacco mosaic virus
1986
Isolation and sequencing of cDNA clones homologous to the v-fgr oncogene from a human B lymphocyte cell line, IM-9.
1987
Regional location of a novel yes-related proto-oncogene, syn, on human chromosome 6 at band q21.
1986
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
1986 Nature