Standout Papers
Citation Impact
Citing Papers
Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes
2005
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Effect of C1 Inhibitor on Inflammatory and Physiologic Response Patterns in Primates Suffering from Lethal Septic Shock
1998
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
The Role of the Endothelium in Changes in Procoagulant Activity in Sepsis
1998
Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis
2001
Mechanisms of Thrombus Formation
2008 Standout
Pathophysiology of Progressive Nephropathies
1998 Standout
4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease
1999
The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature
1995
Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development
2012
The cytokine‐mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia
1997
Autophagy Is a Component of Epithelial Cell Fate in Obstructive Uropathy
2010
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Exosomal MicroRNA MiR-1246 Promotes Cell Proliferation, Invasion and Drug Resistance by Targeting CCNG2 in Breast Cancer
2017
Drotrecogin Alfa (Activated) in Adults with Septic Shock
2012 Standout
Antithrombin III in patients with severe sepsis
1998
Host–pathogen interactions in sepsis
2007
Cellular pathophysiology of ischemic acute kidney injury
2011 Standout
Tissue Factor-Dependent Coagulation Is Preferentially Up-Regulated within Arterial Branching Areas in a Baboon Model of Escherichia coli Sepsis
2005
In Situ Detection of Tissue Factor within the Coronary Intima in Rat Cardiac Allograft Vasculopathy
1999
Epidemic Meningococcemia and Purpura Fulminans with Induced Protein C Deficiency
1993
Activation of coagulation with concurrent impairment of anticoagulant mechanisms correlates with a poor outcome in severe melioidosis
2007
Melioidosis
2012 Standout
Heat Stroke
2002 Standout
Neutrophils express tissue factor in a monkey model of sepsis
2000
Selective enhancement of the tumour necrotic activity of TNF α with monoclonal antibody
1992
Inflammation and coagulation
2010
Severe Sepsis and Septic Shock
2013 Standout
Disseminated intravascular coagulation: Clinical and laboratory aspects
1998
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
2002
Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial
2003
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression
2017
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock.
1993
Septic Shock, Multiple Organ Failure, and Disseminated Intravascular Coagulation
1992
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
1998 StandoutNobel
New Insights into the Regulation of Epithelial–Mesenchymal Transition and Tissue Fibrosis
2012
Cell biology of tissue factor, the principal initiator of blood coagulation
1996
Mutation in blood coagulation factor V associated with resistance to activated protein C
1994 StandoutNature
The Protein C Pathway
2003
Coagulation disorders in septic shock
1993
Combinatorial infection andin vivorecombination: a strategy for making large phage antibody repertoires
1993 StandoutNobel
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
1995
Cachectin, Cachexia, and Shock
1988 StandoutNobel
Point-of-care immunotesting: Approaching the analytical performance of central laboratory methods
2005
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.
1994
Resistance to Activated Protein C as a Basis for Venous Thrombosis
1994 Standout
Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
2014
Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies
2002
Risks and Benefits of Activated Protein C Treatment for Severe Sepsis
2002
EMT: 2016
2016 Standout
Telomere Shortening in Kidneys with Age
2000
The present and future role of microfluidics in biomedical research
2014 StandoutNature
Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection
2005 Standout
The Pathophysiology and Treatment of Sepsis
2003 Standout
Dedifferentiation and Proliferation of Surviving Epithelial Cells in Acute Renal Failure
2003
Activated protein C prevents multiple organ injury following extensive hepatectomy in cirrhotic rats
2000
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2001 Standout
The basics of epithelial-mesenchymal transition
2009 Standout
Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation
2004
Disseminated Intravascular Coagulation
1999 Standout
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans
1997
Points of control in inflammation
2002 StandoutNature
Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride-induced septic shock
2009
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
1993
Reassessment of Exosome Composition
2019 Standout
Identification of a subpopulation of human renal microvascular endothelial cells with capacity to form capillary-like cord and tube structures
1997
Microfluidic diagnostic technologies for global public health
2006 StandoutNature
RNA delivery by extracellular vesicles in mammalian cells and its applications
2020
Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
1999 StandoutNobel
Role of NFkappaB in the mortality of sepsis.
1997
The Epidemiology of Sepsis in the United States from 1979 through 2000
2003 Standout
Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment
2000 StandoutNobel
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion
2006
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Blockage of Tubular Epithelial to Myofibroblast Transition by Hepatocyte Growth Factor Prevents Renal Interstitial Fibrosis
2002
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Intensive Insulin Therapy in Critically Ill Patients
2001 Standout
Characteristic effects of activated human protein C on tissue thromboplastin-induced disseminated intravascular coagulation in rabbits
1994
Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer
2017
Gene Expression Profile of Antithrombotic Protein C Defines New Mechanisms Modulating Inflammation and Apoptosis
2001
Effects of human soluble thrombomodulin on experimental glomerulonephritis
2002 StandoutNobel
Extracellular histones are major mediators of death in sepsis
2009 Standout
The immunopathogenesis of sepsis
2002 StandoutNature
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4
1998 Standout
Fortnightly Review: Disseminated intravascular coagulation: diagnosis and treatment
1996
The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation
1989
Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients
1996
Magnesium in Man: Implications for Health and Disease
2014 Standout
Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney.
1996 StandoutNobel
Effects on Coagulation and Fibrinolysis Induced by Influenza in Mice With a Reduced Capacity to Generate Activated Protein C and a Deficiency in Plasminogen Activator Inhibitor Type 1
2006
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Molecular insights into renal interstitial fibrosis.
1996
Structure and Function of Lipopolysaccharide Binding Protein
1990 StandoutScience
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
1996
Interleukin-10 Inhibits Activation of Coagulation and Fibrinolysis During Human Endotoxemia
1997
The cytoprotective protein C pathway
2006
Introduction: are natural anticoagulants candidates for modulating the inflammatory response to endotoxin?
2000
CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein
1990 StandoutScience
Recombinant human antithrombin III improves survival and attenuates inflammatory responses in baboons lethally challenged with Escherichia coli
2000
The interactions between inflammation and coagulation
2005
Anti-Inflammatory, Antithrombotic, and Neuroprotective Effects of Activated Protein C in a Murine Model of Focal Ischemic Stroke
2001
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Role of Tissue Factor in Adhesion of Mononuclear Phagocytes to and Trafficking Through Endothelium In Vitro
1998
Phosphatidylethanolamine incorporation into vesicles selectively enhances factor Va inactivation by activated protein C.
1994
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis
2000
Coagulation and inflammation
2001
Recombinant human protein C, protein S and thrombomodulin as antithrombotics
1994
Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway
2002 Science
The protein C anticoagulant pathway.
1992
Early role of Fsp1 in epithelial-mesenchymal transformation
1997
Tissue Factor and Factor VIIa Receptor/Ligand Interactions Induce Proinflammatory Effects in Macrophages
1999
Protease-Activated Receptor 1 Mediates Thrombin-Dependent, Cell-Mediated Renal Inflammation in Crescentic Glomerulonephritis
2000
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Regulation and functions of the protein C anticoagulant pathway.
1999
Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.
1988
Heparin Blunts Endotoxin-Induced Coagulation Activation
1999
Disseminated Intravascular Coagulation
1999
Pathogenesis of DIC in Sepsis
1999
Inflammation, sepsis, and coagulation.
1999
Direct detection of activated protein C in blood from human subjects
1992
The interaction of a Ca2+-dependent monoclonal antibody with the protein C activation peptide region. Evidence for obligatory Ca2+ binding to both antigen and antibody.
1988
Works of Kenneth E. Blick being referenced
Plasma exosome microRNAs are indicative of breast cancer
2016
The essential role of information management in point-of-care/critical care testing
2001
Tubular atrophy in the end-stage kidney: A lectin and immunohistochemical study
1994
Staging of the Baboon Response to Group A Streptococci Administered Intramuscularly: A Descriptive Study of the Clinical Symptoms and Clinical Chemical Response Patterns
1999
DEGR-factor Xa blocks disseminated intravascular coagulation initiated by Escherichia coli without preventing shock or organ damage
1991
Proliferative activity of intrinsic cell populations in the normal human kidney.
1994
A Double-Blind Placebo-Controlled Crossover Trial of Intravenous Magnesium Sulfate for Foscarnet-Induced Ionized Hypocalcemia and Hypomagnesemia in Patients with AIDS and Cytomegalovirus Infection
2000
DEGR-factor Xa blocks disseminated intravascular coagulation initiated by Escherichia coli without preventing shock or organ damage
1991
Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody.
1991
C4b-binding protein exacerbates the host response to Escherichia coli
1991
Cell Proliferation in the Developing Human Kidney
1998
Proliferative activity of cyst epithelium in human renal cystic diseases.
1995
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.
1987 Standout
C4b-binding protein exacerbates the host response to Escherichia coli
1991