Ken Ikeuchi

How do cells cope with RNA damage and its consequences?

UCSF ChimeraX: Tools for structure building and analysis

Pathological Proteins in Parkinson's Disease: Focus on the Proteasome

Pathological roles of MAPK signaling pathways in human diseases

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

Parkin genetics: one model for Parkinson's disease

A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides

Parkin negatively regulates JNK pathway in the dopaminergic neurons ofDrosophila

Translation dynamics in human cells visualized at high resolution reveal cancer drug action

Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

RING Domain E3 Ubiquitin Ligases

Physicochemical Foundations of Life that Direct Evolution: Chance and Natural Selection are not Evolutionary Driving Forces

The Ccr4-Not complex monitors the translating ribosome for codon optimality

Ubiquitination of stalled ribosome triggers ribosome-associated quality control

Stress- and ubiquitylation-dependent phase separation of the proteasome

Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3′ end of nonstop mRNA

Recent Progress on the Molecular Mechanism of Quality Controls Induced by Ribosome Stalling

Autosomal recessive juvenile parkinsonism

Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways