Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
2010 StandoutScience
Drosophila dMyc is required for ovary cell growth and endoreplication
2004
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
1997 Nature
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth
1998 Nature
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
The interplay between MYC and HIF in cancer
2007
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Induction of Mxi1-SRα by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression
2007
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival
2005
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression
1997 Nature
Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection
2007
Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A
1997
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Function of the c-Myc Oncogenic Transcription Factor
1999
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
The Mad Side of the Max Network: Antagonizing the Function of Myc and More
2006
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
2007
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
c-Myc-regulated microRNAs modulate E2F1 expression
2005 StandoutNature
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins
1998
The price of repression
1995
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The language of covalent histone modifications
2000 StandoutNature
Sin3: a flexible regulator of global gene expression and genome stability
2004
Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters
1997
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
2005
Genetic control of cell size
2000
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
c-MYC: more than just a matter of life and death
2002
Myc Target Transcriptomes
2006
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
Lessons Learned from Myc/Max/Mad Knockout Mice
2006
The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc
2000
c-Myc/Max Heterodimers Bind Cooperatively to the E-Box Sequences Located in the First Intron of the Rat Ornithine Decarboxylase (ODC) Gene
1997
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network
2003
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
A transcriptional co-repressor that interacts with nuclear hormone receptors
1995 StandoutNature
E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
2002
Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila
2005 Nobel
The c‐myc Promoter: Still MysterY and Challenge
2007
A Role for Mammalian Sin3 in Permanent Gene Silencing
2008 StandoutNobel
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
1995 StandoutNature
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
1999
Expression ofmyc-family,myc-interacting, andmyc-target genes during preimplantation mouse development
1997
Chromatin crosstalk in development and disease: lessons from REST
2007
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
Myc/Max/Mad in Invertebrates: The Evolution of the Max Network
2006
HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation
2007
c-Myc regulates mammalian body size by controlling cell number but not cell size
2001 NatureNobel
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex
1997
Reflecting on 25 years with MYC
2008 Standout
Silencing of microRNAs in vivo with ‘antagomirs’
2005 StandoutNature
Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock
2011 StandoutNobel
Control of cell growth by c-Myc in the absence of cell division
1999
Translocations involving c-myc and c-myc function
2001
Structural Aspects of Interactions Within the Myc/Max/Mad Network
2006
Drosophila myc Regulates Cellular Growth during Development
1999
Histone acetylation in chromatin structure and transcription
1997 StandoutNature
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes
1999
Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression
1997
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1998 StandoutNature
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53
1998
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase
1997
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
2003
The Mlx Network: Evidence for a Parallel Max-Like Transcriptional Network That Regulates Energy Metabolism
2006
Myc in model organisms: A view from the flyroom
2006
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
2000
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination.
1997
Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation
2008
c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism
1999
The coregulator exchange in transcriptional functions of nuclear receptors
2000 Standout
Cancer Cell Cycles
1996 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
The MAX-interacting transcription factor network
2006
dMyc is required for larval growth and endoreplication in Drosophila
2004
Mnt Takes Control as Key Regulator of the Myc/Max/Mxd Network
2007
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
The Myc/Max/Mad Network and the Transcriptional Control of Cell Behavior
2000
Loss of HCF-1–Chromatin Association Precedes Temperature-Induced Growth Arrest of tsBN67 Cells
2001
ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION
1998
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.
1995
The Max Network Gone Mad
2001
Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion
2001 StandoutNobel
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms
2000
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
The Transcriptional Repressor dMnt Is a Regulator of Growth in Drosophila melanogaster
2005
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
The Smad transcriptional corepressor TGIF recruits mSin3.
2001
Works of Ken Chen being referenced
An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3
1995
Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype
1997
Identification of Mammalian Sds3 as an Integral Component of the Sin3/Histone Deacetylase Corepressor Complex
2002