Citation Impact
Citing Papers
Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
2011
LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
2021
DMAP: a connectivity map database to enable identification of novel drug repositioning candidates
2015
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Transcriptional data: a new gateway to drug repositioning?
2012
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis
2012
idTarget: a web server for identifying protein targets of small chemical molecules with robust scoring functions and a divide-and-conquer docking approach
2012
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
2016 Standout
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Targeting hypoxia in cancer therapy
2011 Standout
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations
2016
Navigating the kinome
2011
Deciphering Diseases and Biological Targets for Environmental Chemicals using Toxicogenomics Networks
2010
Elucidating Compound Mechanism of Action by Network Perturbation Analysis
2015
Open Babel: An open chemical toolbox
2011 Standout
Frequent hitters: nuisance artifacts in high-throughput screening
2020
PLIP: fully automated protein–ligand interaction profiler
2015 Standout
Serotonin, But Not N -Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo
2010
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Tools for in silico target fishing
2014
ChEMBL: a large-scale bioactivity database for drug discovery
2011 Standout
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
2015
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
2021
DrugBank 4.0: shedding new light on drug metabolism
2013 Standout
Network-Based Relating Pharmacological and Genomic Spaces for Drug Target Identification
2010
Old friends in new guise: repositioning of known drugs with structural bioinformatics
2011
How Ligands Illuminate GPCR Molecular Pharmacology
2017
Network medicine: a network-based approach to human disease
2010 Standout
Computational Methods in Drug Discovery
2014
Molecular Dynamics Simulation for All
2018 Standout
On the Integration of In Silico Drug Design Methods for Drug Repurposing
2017
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Target identification and mechanism of action in chemical biology and drug discovery
2013
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements
2010
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Biochemical network-based drug-target prediction
2010
FragmentStore--a comprehensive database of fragments linking metabolites, toxic molecules and drugs
2010
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases
2016
Drug repurposing: progress, challenges and recommendations
2018 Standout
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
Polypharmacology in Drug Discovery: A Review from Systems Pharmacology Perspective
2016
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks
2012 StandoutNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
A survey of yeast genomic assays for drug and target discovery
2010
SwissTargetPrediction: a web server for target prediction of bioactive small molecules
2014
DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome
2011
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds
2018
Systematic Drug Repositioning Based on Clinical Side-Effects
2011
The neural basis of psychedelic action
2022 Standout
Large-scale prediction and testing of drug activity on side-effect targets
2012 Nature
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
The ChEMBL database in 2017
2016 Standout
Exploiting drug-disease relationships for computational drug repositioning
2011
Identification of Odorant-Receptor Interactions by Global Mapping of the Human Odorome
2014
Emerging Topics in Structure-Based Virtual Screening
2013
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
Keystone taxa as drivers of microbiome structure and functioning
2018 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
2010 Standout
A Structure-Based Approach for Mapping Adverse Drug Reactions to the Perturbation of Underlying Biological Pathways
2010
Orthogonal photoswitching in a multifunctional molecular system
2016 StandoutNobel
Kinase inhibition-related adverse events predicted from in vitro kinome and clinical trial data
2010
Visible‐Light‐Driven Photoisomerization and Increased Rotation Speed of a Molecular Motor Acting as a Ligand in a Ruthenium(II) Complex
2015 StandoutNobel
The promises and perils of psychedelic pharmacology for psychiatry
2022
Optochemical Genetics
2011
Computational Drug Repositioning: From Data to Therapeutics
2013
Leveraging big data to transform target selection and drug discovery
2015
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data
2011
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Integrative methods for analyzing big data in precision medicine
2015
Modulatory profiling identifies mechanisms of small molecule-induced cell death
2011
Predicting New Indications for Approved Drugs Using a Proteochemometric Method
2012
Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS
2012
Correction: Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements
2010
Multiple Sclerosis
2018 Standout
Discovery of drug mode of action and drug repositioning from transcriptional responses
2010
Updates on drug–target network; facilitating polypharmacology and data integration by growth of DrugBank database
2015
Extended-Connectivity Fingerprints
2010 Standout
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
2019 Standout
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors
2010
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Shaping the interaction landscape of bioactive molecules
2013
Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19
2020
In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA)
2019
The Chemical Basis of Pharmacology
2010
Similarity-based machine learning methods for predicting drug–target interactions: a brief review
2013
o-Fluoroazobenzenes as Readily Synthesized Photoswitches Offering Nearly Quantitative Two-Way Isomerization with Visible Light
2012 Standout
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Polypharmacology: Challenges and Opportunities in Drug Discovery
2014
Emerging Targets in Photopharmacology
2016 StandoutNobel
Protein homology reveals new targets for bioactive small molecules
2015
PubChem in 2021: new data content and improved web interfaces
2020 Standout
The scoring bias in reverse docking and the score normalization strategy to improve success rate of target fishing
2017
Optochemische Genetik
2011
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Works of Kelan Thomas being referenced
Predicting new molecular targets for known drugs
2009 Nature
A pilot study of the pharmacodynamic impact of SSRI drug selection and beta-1 receptor genotype (ADRB1) on cardiac vital signs in depressed patients: a novel pharmacogenetic approach.
2010