Citation Impact
Citing Papers
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
How chemokines organize the tumour microenvironment
2023
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor
1991
Eukaryotic activators function during multiple steps of preinitiation complex assembly
1993 Nature
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Yeast and human TFIID with altered DNA-binding specificity for TATA elements
1992
Cloning of a human gene encoding the general transcription initiation factor IIB
1991 Nature
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Recycling of the general transcription factors during RNA polymerase II transcription.
1995
Fusion tails for the recovery and purification of recombinant proteins
1991
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Family of proteins that interact with TFIID and regulate promoter activity
1991
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
Mechanism and Regulation of Yeast RNA Polymerase II Transcription
1998 StandoutNobel
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation
1991
TBP, a universal eukaryotic transcription factor?
1993
Reduced binding of TFIID to transcriptionally compromised mutants of VP16
1991 Nature
Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells
1993 Nature
The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization
2006
Cell type-specific functions of Rho GTPases revealed by gene targeting in mice
2006
Mediator and the mechanism of transcriptional activation
2005 StandoutNobel
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Structure and function of transcriptional activation domains
1995
Transcriptional activation by viral regulatory proteins
1991
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly
1991
Mammalian Rho GTPases: new insights into their functions from in vivo studies
2008 Standout
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
1995 StandoutNobel
A highly conserved domain of TFIID displays species specificity in vivo
1991
Mediator of transcriptional regulation
1996
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals
1990 Nature
Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains
1992
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis
2002
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Mechanism of action of an acidic transcriptional activator in vitro
1991
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication
1993
Functional differences between yeast and human TFIID are localized to the highly conserved region
1991
GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
2007
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
The interactions of transcription factors and their adaptors, coactivators and accessory proteins
1991
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes
1991
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Transcriptional activation by recruitment
1997 Nature
Dominant negative mutations in yeast TFIID define a bipartite DNA-binding region
1991
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
An Activator Target in the RNA Polymerase II Holoenzyme
1998
Mechanisms of transactivation by retinoic acid receptors
1993
Irresistible force meets immovable object: Transcription and the nucleosome
1991 StandoutNobel
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.
1991
Structural organization of yeast and mammalian mediator complexes
2000 StandoutNobel
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein
1991 Science
An ATP-dependent inhibitor of TBP binding to DNA.
1993
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Delineation of two functional regions of transcription factor TFIIB.
1993
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes
1996
A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID.
1992
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
The highly pleiotropic gene SLC39A8 as an opportunity to gain insight into the molecular pathogenesis of schizophrenia
2017
TFIIB or not TFIIB?
1991 Nature
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
1993
Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator.
1993
Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation.
1993
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
2007
Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
1993 StandoutNobel
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.
1991
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
1993 StandoutNobel
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.
1994
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
1995 StandoutNobel
Contact with a component of the polymerase II holoenzyme suffices for gene activation
1995
Transcription factor TFIID induces DNA bending upon binding to the TATA element.
1992
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
1993
Adopt a moratorium on heritable genome editing
2019 StandoutNatureNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Conserved Structures of Mediator and RNA Polymerase II Holoenzyme
1999 StandoutScienceNobel
TFIIA induces conformational changes in TFIID via interactions with the basic repeat.
1992
Mediator of Transcriptional Regulation
2000 StandoutNobel
RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro.
1994
Complete, 12-subunit RNA polymerase II at 4.1-Å resolution: Implications for the initiation of transcription
2003 StandoutNobel
Transcriptional activation in yeast by the proline-rich activation domain of human CTF1.
1993
Mapping the transcriptional transactivation function of simian virus 40 large T antigen
1991
A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors.
1994
A Transcriptional Mediator Protein That Is Required for Activation of Many RNA Polymerase II Promoters and Is Conserved from Yeast to Humans
1997
Two distinct domains in the yeast transcription factor IID and evidence for a TATA box-induced conformational change.
1991
Association of an activator with an RNA polymerase II holoenzyme.
1995
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Krüppel-associated boxes are potent transcriptional repression domains.
1994
TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.
1992
TFIIA Induces Conformational Changes in TFIID via Interactions with the Basic Repeat
1992
A Highly Conserved Domain of RNA Polymerase II Shares a Functional Element with Acidic Activation Domains of Upstream Transcription Factors
1994
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts.
1991
Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
1993
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow
2007
Functional domains of the Drosophila Engrailed protein.
1993
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
An Activator Binding Module of Yeast RNA Polymerase II Holoenzyme
1999
Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells
1998 StandoutScienceNobel
A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.
1994 StandoutNobel
RNA polymerase II carboxy-terminal domain contributes to the response to multiple acidic activators in vitro.
1991
Transcription Factor IID Mutants Defective for Interaction with Transcription Factor IIA
1992 Science
Yeast and human TFIIDs are interchangeable for the response to acidic transcriptional activators in vitro.
1992 StandoutNobel
Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau).
1992
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton
2006
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
1997 StandoutNobel
Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein.
1993
Works of Keith Stringer being referenced
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization
2005
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID
1990 Nature
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis
2005
Loss of Serum Response Element-Binding Activity and Hyperphosphorylation of Serum Response Factor during Cellular Aging
1994
The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth
2006