Citation Impact
Citing Papers
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Presence of interleukin 10 (IL-10) in the ascites of patients with ovarian and other intra-abdominal cancers
1992
Adenoviral Transfer of the Viral IL-10 Gene Periarticularly to Mouse Paws Suppresses Development of Collagen-Induced Arthritis in Both Injected and Uninjected Paws
1999
Interleukin 10 (IL-10): an immunosuppressive factor and independent predictor in patients with metastatic renal cell carcinoma
1999
The DNA-damage response in human biology and disease
2009 StandoutNature
Functional diversity of helper T lymphocytes
1996 StandoutNature
Biological properties of interleukin 10
1992
Interleukin-10 Stimulation of Phosphatidylinositol 3-Kinase and p70 S6 Kinase Is Required for the Proliferative but Not the Antiinflammatory Effects of the Cytokine
1996
Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
2000
Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy
2000
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Triplet Repeat Expansion Mutations: The Example of Fragile X Syndrome
1995
Interleukin-10 Inhibition of HLA-DR Expression in Human Herpes Stromal Keratitis
1994
Inflammation and cancer
2002 StandoutNature
Relationship of Interleukin-10 Plasma Levels to Severity of Injury and Clinical Outcome in Injured Patients
1997
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes.
1995
Increased mRNA Expression of IL‐10 in Mononuclear Cells in Multiple Sclerosis and Optic Neuritis
1995
RETROVIRAL DELIVERY OF VIRAL INTERLEUKIN-10 INTO MYELOID DENDRITIC CELLS MARKEDLY INHIBITS THEIR ALLOSTIMULATORY ACTIVITY AND PROMOTES THE INDUCTION OF T-CELL HYPORESPONSIVENESS1,2
1998
Elevated interleukin-10 levels in patients with rheumatoid arthritis
1995
Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene
1997
IL-10 Inhibits the Primary Allogeneic T Cell Response to Human Peripheral Blood Dendritic Cells
1995
Expansion of an unstable DNA region and phenotypic variation in myotonic dystrophy
1992 Nature
Suppressive Effects of Interleukin‐10 on Human Mononuclear Phagocyte Function againstCandida albicansandStaphylococcus aureus
1998
Unstable DNA sequence in myotonic dystrophy
1992
Myotonic dystrophy, knockouts, warts
1996
Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP
1997
Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts
2000
Interleukin 10 production correlates with pathology in human Leishmania donovani infections.
1993
Characterization of the expression of DMPK and SIX5 in the human eye and implications for pathogenesis in myotonic dystrophy
1999
Effects of single intravenous doses of recombinant human interleukin-10 on subsets of circulating leukocytes in humans
1999
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins
2002
IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages
1998
Pms2 is a genetic enhancer of trinucleotide CAG{middle dot}CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion
2004
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase
2000
Tr1 cells: From discovery to their clinical application
2006
Immune complexes inhibit antimicrobial responses through interleukin-10 production. Effects in severe combined immunodeficient mice during Listeria infection.
1995
Regulatory T Cells
2000 StandoutNobel
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
2003
Effect of interleukin‐10 on dendritic cell maturation and function
1997
Downregulation of Cytokine-induced Neutrophil Chemoattractant and Prolongation of Rat Liver Allograft Survival by Interleukin-10
1998
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
2000
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Interleukin‐10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells
1994
UNC-39, the C. elegans homolog of the human myotonic dystrophy-associated homeodomain protein Six5, regulates cell motility and differentiation
2004 StandoutNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages
1992
SYSTEMIC ADMINISTRATION OF ANTI-INTERLEUKIN-10 ANTIBODY PROLONGS ORGAN ALLOGRAFT SURVIVAL IN NORMAL AND PRESENSITIZED RECIPIENTS1,2
1998
The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene
1993
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.
1993
Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity
2000
Interleukin-10 Down-Regulates MHC Class II αβ Peptide Complexes at the Plasma Membrane of Monocytes by Affecting Arrival and Recycling
1997
In vivo effects of interleukin-10 on human cytochrome P450 activity
2000
Interleukin‐10 inhibition of the progression of established collagen‐induced arthritis
1996
CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus
2001
Slipped-strand DNAs formed by long (CAG)middle dot(CTG) repeats: slipped-out repeats and slip-out junctions
2002
Triplet repeat mutations in human disease
1992 Science
Genomic Cloning and Characterization of the Human Homeobox Gene SIX6 Reveals a Cluster of SIX Genes in Chromosome 14 and Associates SIX6 Hemizygosity with Bilateral Anophthalmia and Pituitary Anomalies
1999
Expandable DNA repeats and human disease
2007 Nature
Allograft transduction of IL-10 prolongs survival following orthotopic liver transplantation
1999
The complex pathology of trinucleotide repeats
1997
MSH2 ATPase Domain Mutation Affects CTG•CAG Repeat Instability in Transgenic Mice
2009
Interleukin-10 in Non-Hodgkin's Lymphoma
1997
SYSTEMIC ADMINISTRATION OF CELLULAR INTERLEUKIN-10 CAN EXACERBATE CARDIAC ALLOGRAFT REJECTION IN MICE1,2
1996
Mapping of the interleukin‐10/interleukin‐10 receptor combining site
1998
CTG repeat instability and size variation timing in DNA repair-deficient mice
2003
Six family genes-structure and function as transcription factors and their roles in development
2000
Human Interleukin-10 Expression in T/Natural Killer-Cell Lymphomas
1998
Interleukin-10 (IL-10) Augments Allograft Arterial Disease
1999
LONG-TERM ALLOGRAFT ACCEPTANCE IN A PATIENT WITH POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDER
1997
Increased interleukin-10 serum levels in patients with solid tumours
1996
Interleukin‐10 prevents experimental allergic encephalomyelitis in rats
1994
Biological properties of interleukin 10
1992
Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury
1996
Interleukin 10 Treatment Does Not Prolong Experimental Corneal Allograft Survival
1999
Adenovirus-Mediated Gene Transfer of Viral Interleukin-10 Inhibits the Immune Response to Both Alloantigen and Adenoviral Antigen
1997
Type 1/Type 2 Immunity in Infectious Diseases
2001
Interleukin-10 inhibits apoptotic cell death in infectious mononucleosis T cells.
1994
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
Repeat expansion disease: progress and puzzles in disease pathogenesis
2010
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
1998
Characterization of Cardiac Conduction System Abnormalities in Mice with Targeted Disruption of Six5 Gene
2002
The human interleukin-10 receptor gene maps to chromosome 11q23.3
1995
Interleukin‐10 Down‐Regulates Oxidative Metabolism and Antibody‐Dependent Cellular Cytotoxicity of Human Neutrophils
1997
CD4+ T Cell Clones Producing both Interferon-γ and Interleukin-10 Predominate in Bronchoalveolar Lavages of Active Pulmonary Tuberculosis Patients
1999
IL-10 expression is associated with the expression of platelet-derived endothelial cell growth factor and prognosis in oral and oropharyngeal carcinoma
1999
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
2000
Intracoronary adenovirus-mediated transfer of immunosuppressive cytokine genes prolongs allograft survival
1997
The Inhibition of HIV Replication in Monocytes by Interleukin 10 Is Linked to Inhibition of Cell Differentiation
1996
The interleukin-10 homolog encoded by Eepstein-Barr virus enhances the reactivation of virus-specific cytotoxic T cell and HLA-unrestricted killer cell responses
1992
Myotonic Dystrophy Is Associated with a Reduced Level of RNA from the DMWD Allele Adjacent to the Expanded Repeat
1999
Reverse Mutation in Myotonic Dystrophy
1993
Atherosclerosis — An Inflammatory Disease
1999 Standout
Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction.
1994
The Fas Death Factor
1995 StandoutScience
Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa
1999
Regulation of Tumor Growth and Metastasis by Interleukin-10: The Melanoma Experience
1999
Structure of the human DNA ligast I gene
1992 StandoutNobel
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection.
1994
The role of free radicals in asbestos-induced diseases
1992
A PILOT TRIAL OF RECOMBINANT HUMAN INTERLEUKIN-10 IN KIDNEY TRANSPLANT RECIPIENTS RECEIVING OKT3 INDUCTION THERAPY1,2
1997
Disposition of Recombinant Human Interleukin‐10 in Subjects with Various Degrees of Renal Function
1999
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Antimetastatic and Antitumor Activities of Interleukin 10 in a Murine Model of Breast Cancer
1996
Progression of Mycosis Fungoides Is Associated with Increasing Cutaneous Expression of Interleukin-10 mRNA
1996
The Caenorhabditis elegans Six/sine oculis Class Homeobox Gene ceh-32 Is Required for Head Morphogenesis
2001
Interleukin‐10 inhibits B7 and intercellular adhesion molecule‐1 expression on human monocytes
1994
High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations
2012
The Hallmarks of Aging
2013 Standout
IL-10 suppresses cell surface CD23/Fc?RII expression, not by enhancing soluble CD23 release, but by reducing CD23 mRNA expression in human monocytes
1996
Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein.
1994
Correlation between CTG trinucleotide repeat length and frequency of severe congenital myotonic dystrophy
1992
Mechanisms of trinucleotide repeat instability during human development
2010
Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging
2012
DIFFERENTIAL EFFECTS OF EXOGENOUS INTERLEUKIN-10 ON CARDIAC ALLOGRAFT SURVIVAL1,2
1999
Expression of interleukin 10 in human melanoma
1994
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.
1994
The familial periodic paralyses and nondystrophic myotonias
1998
Prolongation of cardiac allograft survival with intracoronary viral interleukin-10 gene transfer
1999
A review of the association between interleukin-10 and human B-cell malignancies
1998
Detection of soluble interleukin-2 receptor and interleukin-10 in the serum of patients with aggressive non-Hodgkin's lymphoma.Identification of a subset at high risk of treatment failure
1994
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Channelopathies: ion channel disorders of muscle as a paradigm for paroxysmal disorders of the nervous system
1997
Interleukin-10 Gene Transfer to the Airway Regulates Allergic Mucosal Sensitization in Mice
1999
Impaired antigen presentation by human monocytes during endotoxin tolerance
2000
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression
1996
MONOCYTES ARE TARGET CELLS FOR IL-10 INDUCTION BY HIV-1 NEF PROTEIN
2000
A receptor for interleukin 10 is related to interferon receptors.
1993
Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors.
1995
MSH2-Dependent Germinal CTG Repeat Expansions Are Produced Continuously in Spermatogonia from DM1 Transgenic Mice
2003
Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis
1998
T Cell-Derived IL-10 Promotes Lung Cancer Growth by Suppressing Both T Cell and APC Function
1999
Interleukin-10–Treated Human Dendritic Cells Induce a Melanoma-Antigen–Specific Anergy in CD8+ T Cells Resulting in a Failure to Lyse Tumor Cells
1999
Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis
1997
High levels of circulating IL-10 in human malaria
1994
Mutational processes of simple-sequence repeat loci in human populations.
1994
IL-10 augments CD23 expression on U937 cells and down-regulates IL-4-driven CD23 expression on cultured human blood monocytes: effects of IL-10 and other cytokines on cell phenotype and phagocytosis.
1995
IL-10 Converts Human Dendritic Cells into Macrophage-Like Cells with Increased Antibacterial Activity Against Virulent Mycobacterium tuberculosis
2000
The structural organization and protein composition of lens fiber junctions.
1989
Mutations in aquaporin-1 in Phenotypically Normal Humans Without Functional CHIP Water Channels
1994 StandoutScienceNobel
Serum Interleukin-10 Levels as a Prognostic Factor in Advanced Non-small Cell Lung Cancer Patients
2000
IL-10 Gene Knockout Mice Show Enhanced Th1-Like Protective Immunity and Absent Granuloma Formation FollowingChlamydia trachomatisLung Infection
1999
A Single Amino Acid Determines the Immunostimulatory Activity of Interleukin 10
2000
Characterization of interleukin-10 receptors on human and mouse cells.
1993
Resting Respiratory Tract Dendritic Cells Preferentially Stimulate T Helper Cell Type 2 (Th2) Responses and Require Obligatory Cytokine Signals for Induction of Th1 Immunity
1998
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Interleukin-10 and Gp130 Cytokines in Human Multiple Myeloma
1999
Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.
1995
Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses.
1995
The Drosophila homeobox gene optix is capable of inducing ectopic eyes by an eyeless-independent mechanism
2000
Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: its underlying mechanism in comparison with interleukin-4
1995
Reversal of Proinflammatory Responses by Ligating the Macrophage Fcγ Receptor Type I
1998
Lack of interleukin 10 regulation of antigen presentation‐associated molecules expressed on colonic epithelial cells
1999
Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.
1996
Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production
1996
A Prominent Role for Sp1 During Lipopolysaccharide- Mediated Induction of the IL-10 Promoter in Macrophages
2000
Interleukin-10 Increases Th1 Cytokine Production and Cytotoxic Potential in Human Papillomavirus-Specific CD8+Cytotoxic T Lymphocytes
2000
Production of interleukin-10 by human bronchogenic carcinoma.
1994
Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure.
1995
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Identification of an IL-10-Producing HLA-DR-Negative Monocyte Subset in the Malignant Ascites of Patients with Ovarian Carcinoma That Inhibits Cytokine Protein Expression and Proliferation of Autologous T Cells
1999
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.
1996
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Infection with Mycobacterium avium induces production of interleukin-10 (IL-10), and administration of anti-IL-10 antibody is associated with enhanced resistance to infection in mice
1993
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.
1996
Treatment with anti-interleukin-10 monoclonal antibody enhances early resistance to but impairs complete clearance of Listeria monocytogenes infection in mice
1994
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.
1994
Interleukin 10 (IL-10) regulation of tumour necrosis factor alpha (TNF-alpha) from human alveolar macrophages and peripheral blood monocytes.
1996
Myotonic Dystrophy Mutation: an Unstable CTG Repeat in the 3′ Untranslated region of the Gene
1992 Science
A Transgenic Model to Analyze the Immunoregulatory Role of IL-10 Secreted by Antigen-Presenting Cells
1999
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis.
1996
Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.
1992
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
1993 Standout
Neural Science
2000 StandoutNobel
Induction of hapten-specific tolerance by interleukin 10 in vivo.
1994
Individual Nonobese Diabetic Mice Exhibit Unique Patterns of CD8+ T Cell Reactivity to Three Islet Antigens, Including the Newly Identified Widely Expressed Dystrophia Myotonica Kinase
2004
Macrophage deactivation by interleukin 10.
1991
IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosity.
1996
Directing gene expression to cerebellar granule cells using γ-aminobutyric acid type A receptor α6 subunit transgenes
1997
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.
1994
Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish
1998
Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases
2001
Human interleukin-10 can directly inhibit T-cell growth
1993
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Lipopolysaccharide-dependent induction of IL-10 receptor expression on murine fibroblasts.
1994
The genome of Caenorhabditis elegans.
1995 StandoutNobel
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Constitutive IL-10 Production Accounts for the High NK Sensitivity, Low MHC Class I Expression, and Poor Transporter Associated with Antigen Processing (TAP)-1/2 Function in the Prototype NK Target YAC-1
1998
A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice.
1984
Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor
1993
Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein
1992 StandoutScienceNobel
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.
1994
A new bacteriophage P1–derived vector for the propagation of large human DNA fragments
1994
The major intrinsic protein (MIP) of the bovine lens fiber membrane: Characterization and structure based on cDNA cloning
1984
Anergic T Cells as Suppressor Cells in Vitro
1994 Science
Staining of interleukin-10 predicts clinical outcome in patients with nasopharyngeal carcinoma
1999
Interleukin 10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis.
1996
Lack of Evidence for the Dichotomy of T H 1 and T H 2 Predominance in HIV-Infected Individuals
1994 Science
Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10.
1993
Interleukin-10 Upregulates Tumor Necrosis Factor Receptor Type-II (p75) Gene Expression in Endotoxin-Stimulated Human Monocytes
1997
Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-10
1999
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Immunoregulatory role of interleukin 10 in rheumatoid arthritis.
1994
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells.
1998
The Biology of Chemokines and their Receptors
2000 Standout
Serum interleukin-10 levels in patients with advanced gastrointestinal malignancies
1999
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Human DNA Repair Genes
2001 StandoutScienceNobel
Effect of IL-10 on collagen-induced arthritis in mice
1996
In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen.
1993
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Triplet Repeat Mutations in Human Disease
1992 Science
Cytokine production in the immune response to murine gammaherpesvirus 68
1996 StandoutNobel
Detection of linkage disequilibrium between the myotonic dystrophy locus and a new polymorphic DNA marker.
1991
Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)
2000
Effect of interleukin-10 on NF-kB and AP-1 activities in interleukin-2 dependent CD8 T lymphoblasts
1994
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
1991 Standout
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
1998 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Identification of functional domains on human interleukin 10
1997
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
Interleukin-10 inhibits motility in murine and human B lymphocytes.
1994
T-cell subsets in autoimmunity
1993
Inhibitory and Stimulatory Effects of IL-10 on Human CD8+ T Cells
1998
Expression of myogenin during embryogenesis is controlled by Six/ sine oculis homeoproteins through a conserved MEF3 binding site
1998
Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells
2003
An Unstable Triplet Repeat in a Gene Related to Myotonic Muscular Dystrophy
1992 Science
Works of Keith Johnson being referenced
Comparative O2-. responses of lung macrophages and blood phagocytic cells in the rat. Possible relevance to IgA immune complex induced lung injury.
1987
Cloning of the HumanSIX1Gene and Its Assignment to Chromosome 14
1996
Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes
1994
Characterisation of Expression of mDMAHP, a Homeodomain-Encoding Gene at the Murine DM Locus
1997
Drosophila homolog of the myotonic dystrophy-associated gene, SIX5, is required for muscle and gonad development
2001
Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis
1994
Somatic Instability of the Myotonic Dystrophy (CTG)n Repeat during Human Fetal Development
1997
Genetics and Physiology of the Myotonic Muscle Disorders
1993
Aging: The Reality: Biomarkers of Aging: From Primitive Organisms to Humans
2004
Microsatellite instability in early sporadic breast cancer
1996
Origin of the expansion mutation in myotonic dystrophy
1993
Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy
1993
Recombination events that locate myotonic dystrophy distal to APOC2 on 19q
1989
Cloning of the essential myotonic dystrophy region and mapping of the putative defect
1992 Nature
Over Expression of the Murine Myotonic Dystrophy Protein Kinase in the Mouse Myogenic C2C12 Cell Line Leads to Inhibition of Terminal Differentiation
1998
Myotonic dystrophy: will the real gene pleasestep forward!
1996
Cloning and Chromosomal Localization of Human Cdc42-Binding Protein Kinase β
1999
A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat
1995
Functional analysis of the homeodomain protein SIX5
2000
Myotonic dystrophy: absence of CTG enlarged transcript in congenital forms, and low expression of the normal allele
1993
Biology of disease. Newer concepts in the pathogenesis of immune complex-induced tissue injury.
1982
A new polymorphic probe which defines the region of chromosome 19 containing the myotonic dystrophy locus.
1990
Myotonic dystrophy: size- and sex-dependent dynamics of CTG meiotic instability, and somatic mosaicism.
1993
Mediation of IgA induced lung injury in the rat. Role of macrophages and reactive oxygen products.
1986
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.
1991 Standout
D19S51 is closely linked with and maps distal to the myotonic dystrophy locus on 19q.
1991
Abnormal contractile activity and calcium cycling in cardiac myocytes isolated from dmpk knockout mice
2003
Arrangement of MP26 in lens junctional membranes: Analysis with proteases and antibodies
1983