Citation Impact
Citing Papers
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion
2008
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
2003 StandoutNobel
NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction
2003 Science
Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis.
1996
The trp ion channel family
2001
TRPM7 Regulates Cell Adhesion by Controlling the Calcium-dependent Protease Calpain
2006
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1996 Nature
Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade
1999 StandoutNobel
Plasmalemmal Phosphatidylinositol-4,5-Bisphosphate Level Regulates the Releasable Vesicle Pool Size in Chromaffin Cells
2005 Nobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Requirement for the PDZ Domain Protein, INAD, for Localization of the TRP Store-Operated Channel to a Signaling Complex
1997
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets
1995
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Rac and Rho: The Story Behind Melanocyte Dendrite Formation
2002
Regulation of Drosophila transient receptor potential‐like (TrpL) channels by phospholipase C‐dependent mechanisms
2001
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Wound healing and its impairment in the diabetic foot
2005 Standout
From worm to man: three subfamilies of TRP channels
2000
Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses
1998 Nature
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Calcium signalling: dynamics, homeostasis and remodelling
2003 Standout
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
TRP, TRPL and trouble in photoreceptor cells
1998
TRP channels and lipids: from Drosophila to mammalian physiology
2006
Piezo2 is required for Merkel-cell mechanotransduction
2014 StandoutNatureNobel
Imaging of cAMP Levels and Protein Kinase A Activity Reveals That Retinal Waves Drive Oscillations in Second-Messenger Cascades
2006 StandoutNobel
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
1999 Nature
Prostaglandin E Receptor EP3 Subtype Induces Neurite Retraction via Small GTPase Rho
1996
A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
1996 Nature
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase
1997
Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase
1995
The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF
1995
cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map
2007 StandoutNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Phosphoinositide Regulation of TRP Channels
2014
In Vivo Analysis of the Drosophila Light-Sensitive Channels, TRP and TRPL
1997
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Plasma membrane phosphoinositide organization by protein electrostatics
2005 Nature
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
PIP2 hydrolysis underlies agonist‐induced inhibition and regulates voltage gating of two‐pore domain K+ channels
2005
Differential Coupling of α1-, α2-, and β-Adrenergic Receptors to Mitogen-activated Protein Kinase Pathways and Differentiation in Transfected PC12 Cells
1998
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
Lipid rafts and membrane traffic
2007
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Lysophosphatidic acid: G-protein signalling and cellular responses
1997
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
β2-Adrenergic Receptor Signaling and Desensitization Elucidated by Quantitative Modeling of Real Time cAMP Dynamics
2007 StandoutNobel
TRP Is Cracked but Is CRAC TRP?
1996
Direct observation of the nanoscale dynamics of membrane lipids in a living cell
2008 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen‐processing pathway
2005
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
A role for Piezo2 in EPAC1-dependent mechanical allodynia
2013
Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodia
2000
cAMP-mediated Growth Inhibition in Fibroblasts Is Not Mediated via Mitogen-activated Protein (MAP) Kinase (ERK) Inhibition
1996
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents
2012 StandoutNobel
Independent roles of Rho‐GTPases in growth cone and axonal behavior
2002
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Differential Responses to Nerve Growth Factor and Epidermal Growth Factor in Neurite Outgrowth of PC12 Cells Are Determined by Rac1 Activation Systems
2001
The Growth-Promoting Effect of Low-Density Lipoprotein May Be Mediated by a Pertussis Toxin-Sensitive Mitogen-Activated Protein Kinase Pathway
1997
The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling
1999
Biosensing with plasmonic nanosensors
2008 Standout
Do Phosphatidylinositides Modulate Vertebrate Phototransduction?
2000
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
TRP Channel Proteins and Signal Transduction
2002
Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides
2015
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages
1997
The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts
1995
FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING
1996 Standout
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Regulation of the Actin Cytoskeleton by Thrombin in Human Endothelial Cells: Role of Rho Proteins in Endothelial Barrier Function
1998
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts.
1993
Rac Downregulates Rho Activity
1999
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.
1990 StandoutNobel
Lysophosphatidic acid possesses dual action in cellproliferation.
1994
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Kinetic analysis of receptor-activated phosphoinositide turnover
2003
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.
1993
The TRP Superfamily of Cation Channels
2005
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
PIP2and Proteins: Interactions, Organization, and Information Flow
2002
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Ca2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP
2006
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
1995
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.
1996
Angiotensin II Activates pp60c-srcin Vascular Smooth Muscle Cells
1995
A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells.
1991
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
1998
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.
1993
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts.
1994
Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts.
1993
AXON RETRACTION AND DEGENERATION IN DEVELOPMENT AND DISEASE
2005
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction.
1997
Two G Protein Oncogenes in Human Endocrine Tumors
1990 Science
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.
1993
Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the Gi-p21ras pathway.
1994
OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans
1997
Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization
1997
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Assessment of the Role of the Inositol 1,4,5-Trisphosphate Receptor in the Activation of Transient Receptor Potential Channels and Store-operated Ca2+ Entry Channels
2001
TRP Channels
2007 Standout
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Works of Kees Jalink being referenced
Agonist-induced PIP 2 Hydrolysis Inhibits Cortical Actin Dynamics: Regulation at a Global but not at a Micrometer Scale
2002
Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate
2007
Integrins control motile strategy through a Rho–cofilin pathway
2005
Activation of TRPM7 Channels by Phospholipase C-coupled Receptor Agonists
2006
Correcting Confocal Acquisition to Optimize Imaging of Fluorescence Resonance Energy Transfer by Sensitized Emission
2004
Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins
1989
An emerging role for PtdIns(4,5)P2-mediated signalling in human disease
2005
InsP3 Receptor Is Essential for Growth and Differentiation but Not for Vision in Drosophila
1997
Lysophosphatidic acid: A bioactive phospholipid with growth factor-like properties
1992
The Drosophila Light-Activated Conductance Is Composed of the Two Channels TRP and TRPL
1996
Peptide Diffusion, Protection, and Degradation in Nuclear and Cytoplasmic Compartments before Antigen Presentation by MHC Class I
2003
Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer
2001
Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator
1994
PIP2 signaling in lipid domains: a critical re‐evaluation
2005
Detecting cAMP‐induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator
2004
Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.
1993
Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae.
1993
Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.
1992
Gold-Enhanced Biomolecular Surface Imaging of Cells and Tissue by SIMS and MALDI Mass Spectrometry
2005
Spatial Regulation of Cyclic AMP-Epac1 Signaling in Cell Adhesion by ERM Proteins
2010
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.
1994
Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.
1990
cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts.
1994
The bioactive phospholipid lysophosphatidic acid is released from activated platelets
1993
Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.
1996
Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor.
1996
Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin
1992
Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers.
1992