Citation Impact
Citing Papers
Angiogenic Factors in Diagnosis, Management, and Research in Preeclampsia
2013
Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success
2004
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
2018 StandoutNobel
Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae
2003
Human Cytotrophoblast Expression of the von Hippel–Lindau Protein Is Downregulated during Uterine Invasion in Situ and Upregulated by Hypoxia in Vitro
2001 StandoutNobel
Human placenta and trophoblast development: key molecular mechanisms and model systems
2019
Viral and Bacterial Pathogens at the Maternal‐Fetal Interface
2004
Drug development in preeclampsia: a ‘no go’ area?
2011
Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data
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Endometrial integrins and the establishment of uterine receptivity
1998
Soluble endoglin (sEng) joins the soluble fms-like tyrosine kinase (sFlt) receptor as a pre-eclampsia molecule
2006
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
Embryo Implantation
2000 Standout
Circulating angiogenic factors in gestational proteinuria without hypertension
2009
Cigarette Smoke Exposure and Angiogenic Factors in Pregnancy and Preeclampsia
2008
Epithelial-mesenchymal transition and its implications for fibrosis
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Plasma soluble endoglin concentration in pre‐eclampsia is associated with an increased impedance to flow in the maternal and fetal circulations
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HLA-G, pre-eclampsia, immunity and vascular events
2003
Maternal Vascular Underperfusion: Nosology and Reproducibility of Placental Reaction Patterns
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Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia.
1996
A decrease in maternal plasma concentrations of sVEGFR-2 precedes the clinical diagnosis of preeclampsia
2010
Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost?
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Blockade of the αvβ3 Integrin Adversely Affects Implantation in the Mouse1
2000
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Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis
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Biomarkers in pre-eclampsia: A novel approach to early detection of the disease
2012
Signaling by members of the TGF-β family in vascular morphogenesis and disease
2010
Animal models of preeclampsia; uses and limitations
2011
Maternal Preeclampsia Predicts the Development of Bronchopulmonary Dysplasia
2009
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3
2000
Serum and plasma determination of angiogenic and anti-angiogenic factors yield different results: The need for standardization in clinical practice
2010
Pathological Relevance of Epithelial and Mesenchymal Phenotype Plasticity
1999
Extracellular control of TGFβ signalling in vascular development and disease
2007
The myometrial junctional zone spiral arteries in normal and abnormal pregnancies
2002
Endoglin in angiogenesis and vascular diseases
2008
Fetal death: A condition with a dissociation in the concentrations of soluble vascular endothelial growth factor receptor-2 between the maternal and fetal compartments
2010
Uric Acid and Cardiovascular Risk
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Contribution of the Endothelium to the Glomerular Permselectivity Barrier in Health and Disease
2007
A subset of patients destined to develop spontaneous preterm labor has an abnormal angiogenic/anti-angiogenic profile in maternal plasma: Evidence in support of pathophysiologic heterogeneity of preterm labor derived from a longitudinal study
2009
Trophoblast pseudo-vasculogenesis: faking it with endothelial adhesion receptors
1998
Etiology and pathogenesis of preeclampsia: Current concepts
1998
Inhibition of TGF-β3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies
1999
Lipoprotein subfraction concentrations in preeclampsia: Pathogenic parallels to atherosclerosis
1997
Late sporadic miscarriage is associated with abnormalities in spiral artery transformation and trophoblast invasion
2006
Preeclampsia and small-for-gestational age are associated with decreased concentrations of a factor involved in angiogenesis: Soluble Tie-2
2008
Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins
1998
Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
2007
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
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2005 Standout
The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age
2008
Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis
2014
Regulation of angiogenesis by hypoxia: role of the HIF system
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Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study
2009
Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
1998 Standout
Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial
2011
Low maternal concentrations of soluble vascular endothelial growth factor receptor-2 in preeclampsia and small for gestational age
2008
Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure
2002
Growth factors, proteases and protease inhibitors in the maternal—fetaldialogue
1996
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?
1997
TGF-β signaling in vascular biology and dysfunction
2008
Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia
2016
Midwifery and quality care: findings from a new evidence-informed framework for maternal and newborn care
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Natural killer cells and pregnancy
2002
Placental Stress and Pre-eclampsia: A Revised View
2009
Urinary Placental Growth Factor and Risk of Preeclampsia
2005
Could uric acid have a pathogenic role in pre-eclampsia?
2010
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Automated assays for sVEGF R1 and PlGF as an aid in the diagnosis of preterm preeclampsia: a prospective clinical study
2009
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
2000
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
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Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
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The “Great Obstetrical Syndromes” are associated with disorders of deep placentation
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AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both
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A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia
2009
Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome
2002
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
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The detection, investigation and management of hypertension in pregnancy: full consensus statement
2000
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
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RNAi modulation of placental sFLT1 for the treatment of preeclampsia
2018
Basic and Therapeutic Aspects of Angiogenesis
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HELLP babies link a novel lincRNA to the trophoblast cell cycle
2012
Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia
2000 Nature
Vascular endothelial growth factor and diabetic complications
2008
Unexplained fetal death is associated with increased concentrations of anti-angiogenic factors in amniotic fluid
2010
Mechanisms of angiogenesis and arteriogenesis
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Molecular genetics of preeclampsia and HELLP syndrome — A review
2012
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
1997
Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies
2019
Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia
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Endothelium-Microenvironment Interactions in the Developing Embryo and in the Adult
2007
Prediction of pre-eclampsia in early pregnancy by estimating the spot urinary albumin: creatinine ratio using high-performance liquid chromatography
2011
Factors Regulating Trophoblast Migration and Invasiveness: Possible Derangements Contributing to Pre-eclampsia and Fetal Injury11Studies from the authors’ laboratory summarized in this article were supported by the Canadian Institutes of Health Research Grant MOP-36446
2003
Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors
2008
Recurrent miscarriage
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Calcitonin Gene-Related Peptide (CGRP) and CGRP Receptor Expression at the Human Implantation Site
2002
An imbalance between angiogenic and anti-angiogenic factors precedes fetal death in a subset of patients: results of a longitudinal study
2010
VEGF Inhibition and Renal Thrombotic Microangiopathy
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Reassessment of Exosome Composition
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Molecular mechanisms and clinical applications of angiogenesis
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Recombinant Vascular Endothelial Growth Factor 121 Attenuates Autoantibody-Induced Features of Pre-eclampsia in Pregnant Mice
2010
Antiphospholid antibodies regulate the expression of trophoblast cell adhesion molecules
2002
Elevated serum soluble fms-like tyrosine kinase 1 (sFlt1) level in women with hydatidiform mole
2009
Genes and the preeclampsia syndrome
2008
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
Preeclampsia prevention and management
2000
Pre-eclampsia
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Diagnosis and management of atypical preeclampsia-eclampsia
2008
A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate
2008
Circulating Angiogenic Factors and the Risk of Preeclampsia
2004 Standout
Murine HIP/L29 Is a Heparin-binding Protein with a Restricted Pattern of Expression in Adult Tissues
1998
IL-10 Is an Autocrine Inhibitor of Human Placental Cytotrophoblast MMP-9 Production and Invasion
1999
Preeclampsia: An excessive maternal inflammatory response to pregnancy
1999 Standout
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
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Latest Advances in Understanding Preeclampsia
2005 StandoutScience
Magnesium sulphate versus phenytoin for eclampsia
2010
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Id-2 regulates critical aspects of human cytotrophoblast differentiation, invasion and migration
2000
Urinary tract infection during pregnancy: current concepts on a common multifaceted problem
2018
Preeclampsia Prevention and Management
2000
Regulation of Human Placental Development by Oxygen Tension
1997 Science
Maternal Plasma Concentrations of Soluble Endoglin in Pregnancies with Intrauterine Growth Restriction
2007
Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia
2007
Redefining Preeclampsia Using Placenta-Derived Biomarkers
2013
Tracking placental development in health and disease
2020
Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology
1998
Macrophage-Derived IL-33 Is a Critical Factor for Placental Growth
2013
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.
1995
Magnesium sulphate and other anticonvulsants for women with pre-eclampsia
2010
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Microscopic Imaging and Spectroscopy with Scattered Light
2010
Endothelial Function and Circulating Biomarkers Are Disturbed in Women and Children After Preeclampsia
2011
The Promise of Angiogenic Markers for the Early Diagnosis and Prediction of Preeclampsia
2012
Hypertensive Disorders of Pregnancy
2018 Standout
Report of the Canadian Hypertension Society Consensus Conference: 3. Pharmacologic treatment of hypertensive disorders in pregnancy.
1997
Maternal Genotype and Severe Preeclampsia: A HuGE Review
2014
Preterm labor: One syndrome, many causes
2014 StandoutScience
Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction
2013
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae
2003
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
2007 StandoutNobel
Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia
2013
Animal Models of Preeclampsia
2020
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
Uric Acid Is as Important as Proteinuria in Identifying Fetal Risk in Women With Gestational Hypertension
2005
Works of Kee-Hak Lim being referenced
Angiogenic Factors and the Risk of Adverse Outcomes in Women With Suspected Preeclampsia
2012
HLA-G Isoforms Produced by Placental Cytotrophoblasts and Found in Amniotic Fluid Are Due to Unusual Glycosylation
1998
Complementary Expression of Hip, a Cell-surface Heparan Sulfate Binding Protein, and Perlecan at the Human Fetal-Maternal Interface1
1998
Urinary tract infection during pregnancy, angiogenic factor profiles, and risk of preeclampsia
2015
The use of angiogenic biomarkers to differentiate non-HELLP related thrombocytopenia from HELLP syndrome
2009
Phenytoin Versus Magnesium Sulfate in Preeclampsia: A Pilot Study
2008
Clinical characterization and outcomes of preeclampsia with normal angiogenic profile
2013
Plasma type II phospholipase A2 levels are elevated in severe preeclampsia
1995
Soluble endoglin contributes to the pathogenesis of preeclampsia
2006 Standout
Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy
2007
The clinical utility of serum uric acid measurements in hypertensive diseases of pregnancy
1998
Diagnostic Utility of Soluble FMS-like Tyrosine Kinase 1 and Soluble Endoglin in Hypertensive Diseases of Pregnancy
2008
Circulating Angiogenic Factors and Risk of Adverse Maternal and Perinatal Outcomes in Twin Pregnancies With Suspected Preeclampsia
2012
Circulating Levels of the Antiangiogenic Marker Soluble FMS-Like Tyrosine Kinase 1 Are Elevated in Women With Pregestational Diabetes and Preeclampsia
2007
The use of angiogenic biomarkers to differentiate non-HELLP related thrombocytopenia from HELLP syndrome
2010
Integrin switching regulates normal trophoblast invasion
1994
Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia.
1997
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
2003
Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels
2007
Twin Pregnancy and the Risk of Preeclampsia: Bigger Placenta or Relative Ischemia?
2009