Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Vascular transcellular signaling.
1993
Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies
2016
Prostaglandin Endoperoxide H Synthases-1 and -2
1996
A large data set comparison of protein structures determined by crystallography and NMR: Statistical test for structural differences and the effect of crystal packing
2007
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Concordant Induction of Prostaglandin E2Synthase with Cyclooxygenase-2 Leads to Preferred Production of Prostaglandin E2over Thromboxane and Prostaglandin D2in Lipopolysaccharide-Stimulated Rat Peritoneal Macrophages
1997
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Cytosolic Phospholipase A2 Is Required for Cytokine-induced Expression of Type IIA Secretory Phospholipase A2 That Mediates Optimal Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Rat 3Y1 Fibroblasts
1998
Substrate Binding Is the Rate-limiting Step in Thromboxane Synthase Catalysis
2001
Facile measurement of 1H–15N residual dipolar couplings in larger perdeuterated proteins
2010
Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors
2000
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
2016 Standout
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
Peroxynitrite formed by simultaneous generation of nitric oxide and superoxide selectively inhibits bovine aortic prostacyclin synthase
1996
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death
2004
The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis
2011
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics
2008
Subcellular Localization of Prostaglandin Endoperoxide H Synthases-1 and -2 by Immunoelectron Microscopy
1998
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
2020
Multiple frequency saturation pulses reduce CEST acquisition time for quantifying conformational exchange in biomolecules
2018
Coupling between Cyclooxygenase, Terminal Prostanoid Synthase, and Phospholipase A2
2001
Improved accuracy of 15N–1H scalar and residual dipolar couplings from gradient-enhanced IPAP-HSQC experiments on protonated proteins
2009
Emerging solution NMR methods to illuminate the structural and dynamic properties of proteins
2019
Molecular Cloning of Prostacyclin Synthase from Bovine Endothelial Cells
1997
Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2
2000 Standout
Prostaglandin endoperoxide synthases-1 and -2
1995
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
2010 StandoutNobel
Prostaglandin and thromboxane biosynthesis
1991
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Peroxide-utilizing biocatalysts: structural and functional diversity of heme-containing enzymes
2004
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2
1996 Standout
Atomic-level characterization of disordered protein ensembles
2007
Scrutinizing Molecular Mechanics Force Fields on the Submicrosecond Timescale with NMR Data
2010
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis
1995 Standout
The Membrane Binding Domains of Prostaglandin Endoperoxide H Synthases 1 and 2
1999
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
2001 StandoutNature
At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?
2009 StandoutNobel
Protein Structure Determination from Pseudocontact Shifts Using ROSETTA
2012 StandoutNobel
Obstructive sleep apnoea and its cardiovascular consequences
2008 Standout
Polyguanidines as Chiral Orienting Media for Organic Compounds
2010
The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature
1993 Standout
Molecular Cloning and Expression of Fatty Acid α-Hydroxylase from Sphingomonas paucimobilis
1997
Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides
2021 StandoutNobel
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
2015 Standout
Conformational Properties of a Peptidic Catalyst: Insights from NMR Spectroscopic Studies
2018
Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution
2008 Science
Ion-dependent protein–surface interactions from intrinsic solvent response
2021 StandoutNobel
Protein NMR Structures Refined with Rosetta Have Higher Accuracy Relative to Corresponding X-ray Crystal Structures
2014 StandoutNobel
The orientation of prostaglandin endoperoxide synthases-1 and -2 in the endoplasmic reticulum.
1994
Fast Rescoring Protocols to Improve the Performance of Structure-Based Virtual Screening Performed on Protein–Protein Interfaces
2020
MOLECULAR MECHANISMS OF PROSTAGLANDIN TRANSPORT
1998
The Cation−π Interaction
1997 Standout
A Dipicolinic Acid Tag for Rigid Lanthanide Tagging of Proteins and Paramagnetic NMR Spectroscopy
2008
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
PubChem 2023 update
2022 Standout
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
2013 Standout
Prostanoid biosynthesis and mechanisms of action
1992
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
Characterization of the Fast Dynamics of Protein Amino Acid Side Chains Using NMR Relaxation in Solution
2006
CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data
2013 Standout
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Validation of Molecular Dynamics Simulations of Biomolecules Using NMR Spin Relaxation as Benchmarks: Application to the AMBER99SB Force Field
2007
Quantitative Molecular Ensemble Interpretation of NMR Dipolar Couplings without Restraints
2007
Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis.
1993
Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings
2011 StandoutNobel
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Geometry, Energetics, and Dynamics of Hydrogen Bonds in Proteins: Structural Information Derived from NMR Scalar Couplings
2006
Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells.
1994
The Ubiquitin Code
2012 Standout
Heme-Containing Oxygenases
1996 Standout
PubChem in 2021: new data content and improved web interfaces
2020 Standout
Prostaglandins and Inflammation
2011 Standout
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Structure and Chemistry of Cytochrome P450
2005 Standout
Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion Study
2011 StandoutNobel
Works of Ke Ruan being referenced
Characterization of the structure and membrane interaction of NH2-terminal domain of thromboxane A2 synthase.
1994
Composite Alignment Media for the Measurement of Independent Sets of NMR Residual Dipolar Couplings
2005
Amino-terminal topology of thromboxane synthase in the endoplasmic reticulum.
1993
Fluorine Pseudocontact Shifts Used for Characterizing the Protein–Ligand Interaction Mode in the Limit of NMR Intermediate Exchange
2017
NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43
2019
Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange saturation transfer
2016
The short-neurotoxin-binding regions on the α-chain of human and Torpedo californica acetylcholine receptors
1991
Multiple Alignment Tensors from a Denatured Protein
2006
Primary structure of human thromboxane synthase determined from the cDNA sequence.
1992
Acetylcholine receptor-alpha-bungarotoxin interactions: determination of the region-to-region contacts by peptide-peptide interactions and molecular modeling of the receptor cavity.
1990
NMR Residual Dipolar Couplings as Probes of Biomolecular Dynamics
2006
The polar warhead of a TRIM 24 bromodomain inhibitor rearranges a water‐mediated interaction network
2017