Citation Impact
Citing Papers
Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
2009
The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNFα
2014
High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
2009
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Triple negative breast cancer: unmet medical needs
2010
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Triple negative tumours: a critical review
2007
Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer
2011
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The expression of β-catenin in different subtypes of breast cancer and its clinical significance
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer
2012
Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome
2010
Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
2010
Triple-Negative Breast Cancer
2010 Standout
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis
2012
Breast cancer stem cells: treatment resistance and therapeutic opportunities
2011
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer
2014
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
2009
Targeting hypoxia in cancer therapy
2011 Standout
A view on drug resistance in cancer
2019 StandoutNature
Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence
2013
BRCAness revisited
2016
Inhibition of Aurora-A suppresses epithelial–mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
2008
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Wnt Signaling in Cancer
2012
Pro-senescence therapy for cancer treatment
2011
Appraising iniparib, the PARP inhibitor that never was—what must we learn?
2013
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
2013
Wnt signaling in cancer
2016 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Genetic Interactions in Cancer Progression and Treatment
2011
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances
2012
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas
2011
Expression of Dicer and Drosha in triple-negative breast cancer
2012
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression
2016
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
2011
Histological and molecular types of breast cancer: is there a unifying taxonomy?
2009
Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma
2013
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
How basal are triple‐negative breast cancers?
2008
Fibroblast growth factor signalling: from development to cancer
2010 Standout
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
2013 Nature
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues
2012
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
2010 Standout
Pioneer transcription factors: establishing competence for gene expression
2011
MicroRNA biogenesis pathways in cancer
2015 Standout
BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer
2009
Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer
2008
The essence of senescence: Figure 1.
2010 Standout
Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy
2009
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
2011
Mechanisms of resistance to therapies targeting BRCA-mutant cancers
2013
Differentiation Generates Paracrine Cell Pairs That Maintain Basaloid Mouse Mammary Tumors: Proof of Concept
2011
Identification of direct transcriptional targets of V600EBRAF/MEK signalling in melanoma
2009
The DNA damage response and cancer therapy
2012 Nature
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
EMT: 2016
2016 Standout
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
2011 Standout
An essential microRNA maturing microprocessor complex component DGCR8 is up-regulated in colorectal carcinomas
2013
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
2011
Gene-Expression Signatures in Breast Cancer
2009
Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
2014
Oncogene-induced senescence: the bright and dark side of the response
2010
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
2012
Resistance to therapy caused by intragenic deletion in BRCA2
2008 Nature
The opposing roles of laminin-binding integrins in cancer
2016
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
2010
Therapeutic potential of PARP inhibitors for metastatic breast cancer
2011
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
The functions and regulation of the PTEN tumour suppressor
2012 Standout
The Hallmarks of Aging
2013 Standout
β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells
2015
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma
2011
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C
1998 Standout
Loss of Dicer expression is associated with breast cancer progression and recurrence
2012
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C
1997
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
2010
Genetic variegation of clonal architecture and propagating cells in leukaemia
2010 Nature
Senescence in tumours: evidence from mice and humans
2009
DICER1: mutations, microRNAs and mechanisms
2014
Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
2010
Gatekeeper Mutations Mediate Resistance to BRAF-Targeted Therapies
2010
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Downregulated D icer expression predicts poor prognosis in chronic lymphocytic leukemia
2012
Intratumor Heterogeneity: Seeing the Wood for the Trees
2012
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
2012
Basal-Like Breast Cancer: A Critical Review
2008
miRNA Deregulation in Cancer Cells and the Tumor Microenvironment
2016
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Wnt signaling potentiates nevogenesis
2013
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
2009
Cancer Genome Landscapes
2013 StandoutScience
Controlled Synthesis of End-Functionalized Mannose-6-phosphate Glycopolypeptides for Lysosome Targeting
2016
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies
2009
Canonical Wnt signaling regulates Slug activity and links epithelial–mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
2012
Chemical Glycoproteomics
2016 StandoutNobel
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1 -mutated basal-like breast cancer
2007
Works of Kay Savage being referenced
Aurora-A Regulation of Nuclear Factor-κB Signaling by Phosphorylation of IκBα
2007
A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer
2010
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas
2006
The Collagen Receptor Endo180 (CD280) Is Expressed on Basal-like Breast Tumor Cells and Promotes Tumor Growth In vivo
2007
Metaplastic breast carcinomas are basal‐like tumours
2006
Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue
2008
Caveolin 1 Is Overexpressed and Amplified in a Subset of Basal-like and Metaplastic Breast Carcinomas: A Morphologic, Ultrastructural, Immunohistochemical, and In situ Hybridization Analysis
2007
Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer
2007
A mouse model of basal‐like breast carcinoma with metaplastic elements
2007
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis
2005
The molecular underpinning of lobular histological growth pattern: a genome‐wide transcriptomic analysis of invasive lobular carcinomas and grade‐ and molecular subtype‐matched invasive ductal carcinomas of no special type
2009
Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype
2007
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
2009
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer
2010
Nestin is expressed in basal-like and triple negative breast cancers
2008
Mixed micropapillary–ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components
2009
Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis
2007
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
2010
Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice
2009
MYC amplification in breast cancer: a chromogenic in situ hybridisation study
2006
Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue
2006
Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis
2007
Genomic profile of a secretory breast cancer with an ETV6–NTRK3 duplication
2009
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
2006
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
2007
BRCA1 dysfunction in sporadic basal-like breast cancer
2006
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast
2008
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization
2006
Chronic Hepatitis C Virus Infection in Haemophilic Patients: Clinical Significance of Viral Genotype
1995
PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors
2010