Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
2015 Standout
Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
2016
Sirtuins as regulators of metabolism and healthspan
2012 Standout
PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
2011
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
2014
AMP-activated protein kinase: also regulated by ADP?
2011
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases
2012
mTOR Signaling in Growth Control and Disease
2012 Standout
Current and Future Drug Targets in Weight Management
2010
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels
2008
Adverse Health Effects of Marijuana Use
2014 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
2010
Autophagy and the Integrated Stress Response
2010 Standout
Sirtuin 1 in lipid metabolism and obesity
2011
N-acylethanolamines, anandamide and food intake
2009
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
2016
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
2010
Hallmarks of aging: An expanding universe
2023 Standout
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
NAD+ as a Signaling Molecule Modulating Metabolism
2011
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
2015
Sirtuins, Aging, and Medicine
2011
Sirtuins, Aging, and Metabolism
2011
Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance
2012
Hormonal Regulation of Hepatic Glucose Production in Health and Disease
2011
Can autophagy promote longevity?
2010
Targeting the cannabinoid system for pain relief?
2013
Autophagy: Renovation of Cells and Tissues
2011 Standout
Mitochondria: In Sickness and in Health
2012 Standout
1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase
2009
Coming of age: molecular drivers of aging and therapeutic opportunities
2013
Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
2012
Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
2014
Drug discovery for a new generation of covalent drugs
2012
A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care—an international randomised controlled trial
2012 Standout
SIRT1: recent lessons from mouse models
2010
Genome-Environment Interactions That Modulate Aging: Powerful Targets for Drug Discovery
2011
NAD+ homeostasis in health and disease
2020
Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs
2012
The controversial links among calorie restriction, SIRT1, and resveratrol
2011
AMP-activated protein kinase and its downstream transcriptional pathways
2010
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Autophagy and Aging
2011 Standout
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
2008 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Metabolic Networks of Longevity
2010
Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
2011
Clickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase
2011
How Chemoproteomics Can Enable Drug Discovery and Development
2012
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
2013 Standout
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
2020
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of senescent cells in ageing
2014 StandoutNature
Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis
2009
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
Hyperactive S6K1 Mediates Oxidative Stress and Endothelial Dysfunction in Aging: Inhibition by Resveratrol
2011
The Hallmarks of Aging
2013 Standout
Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies
2015
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
Prediabetes: a high-risk state for diabetes development
2012 Standout
Cannabinoids and the gut: New developments and emerging concepts
2010
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
2010
A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol
2012
Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors
2010
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Clues from cell metabolism
2010 StandoutNatureNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
Properties of Resveratrol:In VitroandIn VivoStudies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans
2015 Standout
Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase
2012
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts
2012
Spermidine in health and disease
2018 StandoutScience
Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells
2020
Synthesis and Evaluation of Substituted Chroman-4-one and Chromone Derivatives as Sirtuin 2-Selective Inhibitors
2012
Proteome-Wide Reactivity Profiling Identifies Diverse Carbamate Chemotypes Tuned for Serine Hydrolase Inhibition
2013
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
The resurgence of covalent drugs
2011
The biology of aging: 1985–2010 and beyond
2011
Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
2015 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
2014
Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides
2017 StandoutNobel
Regulation of mitochondrial biogenesis
2010
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
SirT1 Regulates Adipose Tissue Inflammation
2011
Specific Turn-On Fluorescent Probe with Aggregation-Induced Emission Characteristics for SIRT1 Modulator Screening and Living-Cell Imaging
2015
Non-Peptide Macrocyclic Histone Deacetylase Inhibitors Derived from Tricyclic Ketolide Skeleton
2010
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?
2015
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Chemical Glycoproteomics
2016 StandoutNobel
Works of Kay Ahn being referenced
Mechanistic Characterization of a 2-Thioxanthine Myeloperoxidase Inhibitor and Selectivity Assessment Utilizing Click Chemistry–Activity-Based Protein Profiling
2013
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
2012
Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain
2009
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)
2009
Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain
2011
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
2010
Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders
2009
Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System
2008
Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor
2010
Structure-guided inhibitor design for human FAAH by interspecies active site conversion
2008