Standout Papers
Citation Impact
Citing Papers
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
2007 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
MicroRNA-155 is induced during the macrophage inflammatory response
2007 StandoutNobel
Jinx , an MCMV susceptibility phenotype caused by disruption of Unc13d : a mouse model of type 3 familial hemophagocytic lymphohistiocytosis
2007 StandoutNobel
Self-assembled mRNA vaccines
2021
Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
2023 StandoutNobel
Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages
2007
The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease
2009 StandoutNobel
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin
2019
Transcriptional regulation of macrophage polarization: enabling diversity with identity
2011 Standout
JAK-STAT Signaling: From Interferons to Cytokines
2007
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
Messenger RNA-Based Vaccines Against Infectious Diseases
2020 StandoutNobel
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Genetic analysis of resistance to viral infection
2007 StandoutNobel
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
2013
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Sensitization of IFN-γ Jak-STAT signaling during macrophage activation
2002
Hepatitis E virus persists in the presence of a type III interferon response
2017
ATP-sensitive potassium channels mediate survival during infection in mammals and insects
2007 StandoutNobel
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Signal integration between IFNγ and TLR signalling pathways in macrophages
2006
Inhibitor of κB Kinase ϵ (IKKϵ), STAT1, and IFIT2 Proteins Define Novel Innate Immune Effector Pathway against West Nile Virus Infection
2011
A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity
2019
Recent advances in mRNA vaccine technology
2020 StandoutNobel
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection
2018
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Precis on forward genetics in mice
2007 StandoutNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
The JAK-STAT Pathway at Twenty
2012
SOCS3 Is a Critical Physiological Negative Regulator of G-CSF Signaling and Emergency Granulopoiesis
2004
STAT1 as a key modulator of cell death
2006
Molecular mechanisms of the anti-inflammatory functions of interferons
2007
The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells
2014
An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence
2010 StandoutNobel
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Chemical Probes Identify a Role for Histone Deacetylase 3 in Friedreich's Ataxia Gene Silencing
2009
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift
2021
Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA
2018
Self-amplifying RNA vaccines for infectious diseases
2020
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
2018 StandoutNobel
Comprehensive Integration of Single-Cell Data
2019 Standout
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
2016
Analysis of the MCMV resistome by ENU mutagenesis
2006 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Histone Deacetylase Inhibitors as Anticancer Drugs
2017
Transcriptional repressors: multifaceted regulators of gene expression
2013
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism
2004
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
A Novel Role for IFN-Stimulated Gene Factor 3II in IFN-γ Signaling and Induction of Antiviral Activity in Human Cells
2010
Venezuelan Equine Encephalitis Virus Disrupts STAT1 Signaling by Distinct Mechanisms Independent of Host Shutoff
2009
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Impact of β2 integrin deficiency on mouse natural killer cell development and function
2011 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.
2011
A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
2013
Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations
2015
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Histone Deacetylase Inhibitors: From Bench to Clinic
2008
The Two Faces of Interferon-γ in Cancer
2011
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
An Update on Self-Amplifying mRNA Vaccine Development
2021
New Kids on the Block: RNA-Based Influenza Virus Vaccines
2018
Works of Katrin Ramsauer being referenced
The Stat1 Binding Motif of the Interferon-γ Receptor Is Sufficient to Mediate Stat5 Activation and Its Repression by SOCS3
2001
Phosphorylation of the Stat1 Transactivation Domain Is Required for Full-Fledged IFN-γ-Dependent Innate Immunity
2003
Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design
2017
Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-γ-induciblegbp2gene
2007
Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons
2003
Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase 1
2006
p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation
2002
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding
2011 StandoutNobel