Citation Impact
Citing Papers
Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma
2008
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
Treatment of kidney cancer
2009 StandoutNobel
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
2012
The molecular hallmarks of epigenetic control
2016 Standout
Histone deacetylases and cancer
2007
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Cellular senescence: when bad things happen to good cells
2007 Standout
Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?
2006
Treatment of Obesity with Celastrol
2015 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD)
2009
Heat shock protein 90: The cancer chaperone
2007
Tumor-Associated Macrophages: From Mechanisms to Therapy
2014 Standout
The Epigenomics of Cancer
2007 Standout
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
2006
The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters
2013
Epigenetics in Cancer
2008 Standout
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
2010
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
2008
Acetylation and deacetylation of non-histone proteins
2005
Drug repurposing: progress, challenges and recommendations
2018 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Causes and consequences of microRNA dysregulation in cancer
2009 Standout
Myeloid-derived Suppressor Cells in Cancer Patients
2012
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Light‐Controlled Histone Deacetylase (HDAC) Inhibitors: Towards Photopharmacological Chemotherapy
2015 StandoutNobel
An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function
2007
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate
2010
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
2007
Histone deacetylase inhibitors: molecular mechanisms of action
2007
Histone Deacetylase Inhibitors: An Attractive Therapeutic Strategy Against Breast Cancer
2017
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
2014
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia
2008
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Clonal evolution in cancer
2012 StandoutNature
Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges
2009
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition
2010
Drugging the Cancer Chaperone HSP90
2007
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin
2007
PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases
2008
Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications
2008
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Histone deacetylase inhibitors in hematological malignancies and solid tumors
2015
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
The cancer genome
2009 StandoutNature
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes
2011
Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma
2009 Standout
Explorative Study on Isoform-Selective Histone Deacetylase Inhibitors
2009
New and emerging HDAC inhibitors for cancer treatment
2014
Histone Deacetylase Inhibitors Induce VHL and Ubiquitin-Independent Proteasomal Degradation of Hypoxia-Inducible Factor 1α
2006
Class II Histone Deacetylases Are Associated with VHL-Independent Regulation of Hypoxia-Inducible Factor 1α
2006
Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.
2011
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Transcriptional control of human p53-regulated genes
2008 Standout
Spermidine in health and disease
2018 StandoutScience
Histone Deacetylase Inhibitors: Overview and Perspectives
2007
Rational Combinations Using HDAC Inhibitors
2009
Histone Deacetylase Inhibitors: From Bench to Clinic
2008
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier
2012 StandoutNobel
Histone Deacetylase 6 Regulates Growth Factor-Induced Actin Remodeling and Endocytosis
2007
Causal analysis approaches in Ingenuity Pathway Analysis
2013 Standout
Ribosomopathies: human disorders of ribosome dysfunction
2010
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
2011
Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
2008
Histone deacetylase 10 promotes autophagy-mediated cell survival
2013
Mechanisms of Endocytosis
2009 Standout
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Targeting HDACs: A Promising Therapy for Alzheimer's Disease
2011
Works of Kathy Rocha being referenced
Activity of Suberoylanilide Hydroxamic Acid Against Human Breast Cancer Cells with Amplification of Her-2
2005
Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90
2005
Secondary Resistance to Lenalidomide in Del(5q) MDS Is Associated with CDC25C & PP2A Overexpression.
2009
Abrogation of Heat Shock Protein 70 Induction as a Strategy to Increase Antileukemia Activity of Heat Shock Protein 90 Inhibitor 17-Allylamino-Demethoxy Geldanamycin
2005
A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide
2009
Cotreatment with Vorinostat (Suberoylanilide Hydroxamic Acid) Enhances Activity of Dasatinib (BMS-354825) against Imatinib Mesylate–Sensitive or Imatinib Mesylate–Resistant Chronic Myelogenous Leukemia Cells
2006
Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl–expressing human leukemia cells
2006
Myeloid-Derived Suppressor Cells (MDSC) Are Effectors of Bone Marrow Suppression in Lower Risk Myelodysplastic Syndromes (MDS).
2009