Citation Impact
Citing Papers
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer
2002
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
Telomeric Protein Pin2/TRF1 as an Important ATM Target in Response to Double Strand DNA Breaks
2001
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Identification of Hyperreactive Cysteines within Ryanodine Receptor Type 1 by Mass Spectrometry
2004
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis
2000
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
2002
The DNA damage response pathways: at the crossroad of protein modifications
2007
Cell-cycle checkpoints and cancer
2004 StandoutNature
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
2001
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
Reconstitution of an ATM-Dependent Checkpoint that Inhibits Chromosomal DNA Replication following DNA Damage
2000
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
DNA Damage-induced Association of ATM with Its Target Proteins Requires a Protein Interaction Domain in the N Terminus of ATM
2005
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
The p53 pathway and apoptosis
1999
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
ATM, a central controller of cellular responses to DNA damage
2001
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
2008 Nature
Cancer Risk and the ATM Gene: a Continuing Debate
2000
DNA damage, p53, apoptosis and vascular disease
2007
Postulated Role of Interdomain Interaction within the Ryanodine Receptor in Ca2+ Channel Regulation
2000
A role for p53 in base excision repair
2001
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
The Role of ATM in Telomere Structure and Function
2001
The controlling role of ATM in homologous recombinational repair of DNA damage
2000
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
Sensing of intermediates in V(D)J recombination by ATM
2002
Antiangiogenic therapy—evolving view based on clinical trial results
2012
Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
2000 StandoutNobel
UV-induced Ataxia-telangiectasia-mutated and Rad3-related (ATR) Activation Requires Replication Stress
2004
Functional Link between BLM Defective in Bloom's Syndrome and the Ataxia-telangiectasia-mutated Protein, ATM
2002
ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses
2003
ATM: Genome stability, neuronal development, and cancer cross paths
2001
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
2004
Recombinational DNA repair and human disease
2002
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
The Pore Structure of the Closed RyR1 Channel
2005
Switching and Signaling at the Telomere
2001 StandoutNobel
Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM
2016
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
A Critical Role for Pin2/TRF1 in ATM-dependent Regulation
2002
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
2007
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Involvement of novel autophosphorylation sites in ATM activation
2006
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Mechanisms of switching on p53: a role for covalent modification?
1999
p53 regulation by post-translational modification and nuclear retention in response to diverse stresses
1999
Utilization of Oriented Peptide Libraries to Identify Substrate Motifs Selected by ATM
2000
Caffeine Abolishes the Mammalian G2/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase Activity
2000
The DNA-dependent protein kinase
1999
ATM-dependent phosphorylation of nibrin in response to radiation exposure
2000
De novo discovery of mutated driver pathways in cancer
2011
Identification of Domains of Ataxia-telangiectasia Mutated Required for Nuclear Localization and Chromatin Association
2005
Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53
2001
DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway
2000
Post-translational modification of p53 in tumorigenesis
2004
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
Purification and Characterization of ATM from Human Placenta
2000
The cellular response to p53: the decision between life and death
1999
ATM and ATR: networking cellular responses to DNA damage
2001
A Novel Tel1/ATM N-Terminal Motif, TAN, Is Essential for Telomere Length Maintenance and a DNA Damage Response
2008 StandoutNobel
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.
2001
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation
2014
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
CHK1 and CHK2 are differentially involved in mismatch repair–mediated 6-thioguanine-induced cell cycle checkpoint responses
2004
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Chk2/hCds1 functions as a DNA damage checkpoint in G1by stabilizing p53
2000
ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
2001
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Surfing the p53 network
2000 StandoutNature
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Posttranslational Modifications of p53 in Replicative Senescence Overlapping but Distinct from Those Induced by DNA Damage
2000
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM
1999
Regulation of p53 stability
1999
Role for ATM in DNA damage-induced phosphorylation of BRCA1.
2000
Cancer Genome Landscapes
2013 StandoutScience
A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival
2002
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
1999
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
1999
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
2000
Human DNA Repair Genes
2001 StandoutScienceNobel
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G 1 /S checkpoint activation in response to DNA damage
2001
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Altered Telomere Nuclear Matrix Interactions and Nucleosomal Periodicity in Ataxia Telangiectasia Cells before and after Ionizing Radiation Treatment
1999
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
The Mre11p/Rad50p/Xrs2p Complex and the Tel1p Function in a Single Pathway for Telomere Maintenance in Yeast
2000
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
ATM mutations are associated with inactivation of theARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma
2002
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Katherine E. Keating being referenced
Epidermal Growth Factor Sensitizes Cells to Ionizing Radiation by Down-regulating Protein Mutated in Ataxia-Telangiectasia
2001
Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia
1993
ATM associates with and phosphorylates p53: mapping the region of interaction
1998
Detection of a novel RYR1 mutation in four malignant hyperthermia pedigrees
1994
Detection of a novel common mutation in the ryanodine receptor gene in malignant hyperthermia: implications for diagnosis and heterogeneity studies
1994
ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro
2003
Establishing a molecular taxonomy for epithelial ovarian cancer (EOC) from 363 formalin-fixed paraffin embedded (FFPE) specimens.
2011