Citation Impact
Citing Papers
Incision of DNA–protein crosslinks by UvrABC nuclease suggests a potential repair pathway involving nucleotide excision repair
2002
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
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The Mo-Se active site of nicotinate dehydrogenase
2009
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
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Simultaneous prediction of protein folding and docking at high resolution
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Catalysis at a dinuclear [CuSMo(O)OH] cluster in a CO dehydrogenase resolved at 1.1-Å resolution
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Emergence of symmetry in homooligomeric biological assemblies
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2007
Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase
2005
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
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A New Type of Bacterial Sulfatase Reveals a Novel Maturation Pathway in Prokaryotes
2006
Molecular Basis for Enzymatic Sulfite Oxidation
2008
Mechanism of Release and Fate of Excised Oligonucleotides during Nucleotide Excision Repair
2012 StandoutNobel
Human Mismatch Repair
2005 StandoutNobel
Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase
2008
Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases
1999
The First Mammalian Aldehyde Oxidase Crystal Structure
2012
Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
2008 StandoutNobel
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Synthetic Analogues and Reaction Systems Relevant to the Molybdenum and Tungsten Oxotransferases
2003
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
The ϕ29 DNA polymerase:protein‐primer structure suggests a model for the initiation to elongation transition
2006 StandoutNobel
Molybdenum and tungsten in biology
2002
The Transition to an Elongation Complex by T7 RNA Polymerase Is a Multistep Process
2007
A synthetic hexapeptide designed to resemble a proteinaceous p‐loop nest is shown to bind inorganic phosphate
2012
Molecular cloning, characterization and expression analysis of three aldehyde oxidase genes from Pisum sativum L.
2007
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Human Xanthine Oxidase Changes its Substrate Specificity to Aldehyde Oxidase Type upon Mutation of Amino Acid Residues in the Active Site: Roles of Active Site Residues in Binding and Activation of Purine Substrate
2007
RecA-like motor ATPases—lessons from structures
2004
Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications
2003
Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells
2009
3D Complex: A Structural Classification of Protein Complexes
2006
Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase
2008
Visualizing polynucleotide polymerase machines at work
2006 StandoutNobel
UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke
2006
Mammalian xanthine oxidoreductase – mechanism of transition from xanthine dehydrogenase to xanthine oxidase
2008
Exchangeable oxygens in the vicinity of the molybdenum center of the high-pH form of sulfite oxidase and sulfite dehydrogenase
2009
Toward modeling the high chloride, low pH form of sulfite oxidase: Ka-band ESEEM of equatorial chloro ligands in oxomolybdenum(V) complexes
2007
Computational Enzyme Design
2013 StandoutNobel
Studies of the Mo(V) center of the Y343F mutant of human sulfite oxidase by variable frequency pulsed EPR spectroscopy
2007
The Iron Sulfur Protein AtsB Is Required for Posttranslational Formation of Formylglycine in the Klebsiella Sulfatase
1999
Applications of pulsed EPR spectroscopy to structural studies of sulfite oxidizing enzymes
2012
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
The Role of Tyrosine 343 in Substrate Binding and Catalysis by Human Sulfite Oxidase
2004
Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
2008
The Mechanism of Assembly and Cofactor Insertion into Rhodobacter capsulatus Xanthine Dehydrogenase
2008
Molecular Basis for Multiple Sulfatase Deficiency and Mechanism for Formylglycine Generation of the Human Formylglycine-Generating Enzyme
2005
Plant Sulfite Oxidase as Novel Producer of H2O2
2006
The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes
2003
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress
2005
Substrate Orientation in Xanthine Oxidase
2007
The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases
2003
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Structural Insights into Sulfite Oxidase Deficiency
2005
Rhodobacter capsulatus XdhC Is Involved in Molybdenum Cofactor Binding and Insertion into Xanthine Dehydrogenase
2006
Sulfotransferases and Sulfatases in Mycobacteria
2002 StandoutNobel
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates
2000
Direct Evidence for ArOS Bond Cleavage upon Inactivation of Pseudomonas aeruginosa Arylsulfatase by Aryl Sulfamates
2008
Transcription Initiation in a Single-Subunit RNA Polymerase Proceeds through DNA Scrunching and Rotation of the N-Terminal Subdomains
2008
Active Site Geometry and Substrate Recognition of the Molybdenum Hydroxylase Quinoline 2-Oxidoreductase
2004 Nobel
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Oxidative Half-reaction of Arabidopsis thaliana Sulfite Oxidase
2009
The Role of Active Site Glutamate Residues in Catalysis of Rhodobacter capsulatus Xanthine Dehydrogenase
2004
Riding the sulfur cycle – metabolism of sulfonates and sulfate esters in Gram-negative bacteria
2000
Nucleotide Excision Repair in Human Cells
2013 StandoutNobel
Cell biology of molybdenum
2009
Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann–Pick C1 disease — Lysosomal storage disorders caused by defects of non-lysosomal proteins
2008
Structure of the molybdopterin-bound Cnx1G domain links molybdenum and copper metabolism
2004 Nature
An Extremely Potent Inhibitor of Xanthine Oxidoreductase
2003
Major Conformational Changes During T7RNAP Transcription Initiation Coincide with, and are Required for, Promoter Release
2005
Significance of Plant Sulfite Oxidase
2007
Clue to damage recognition by UvrB: residues in the beta-hairpin structure prevent binding to non-damaged DNA
2001
Mechanisms and structures of crotonase superfamily enzymes – How nature controls enolate and oxyanion reactivity
2008
Proteolysis in the SOS response and metal homeostasis in Escherichia coli
2009
Multiple Sulfatase Deficiency Is Caused by Mutations in the Gene Encoding the Human Cα-Formylglycine Generating Enzyme
2003
Different inhibitory potency of febuxostat towards mammalian and bacterial xanthine oxidoreductases: insight from molecular dynamics
2012
Bacterial sulfite-oxidizing enzymes
2010
A Yeast Four-hybrid System Identifies Cdk-activating Kinase as a Regulator of the XPD Helicase, a Subunit of Transcription Factor IIH
2001
Pulsed EPR investigations of the Mo(V) centers of the R55Q and R55M variants of sulfite dehydrogenase from Starkeya novella
2010
The Role of Arginine 310 in Catalysis and Substrate Specificity in Xanthine Dehydrogenase from Rhodobacter capsulatus
2007
Molybdenum cofactors, enzymes and pathways
2009 Nature
Molybdenum enzymes in higher organisms
2010
Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair
2006
Structure and stability of the molybdenum cofactor intermediate cyclic pyranopterin monophosphate
2011
Molecular Basis of Intramolecular Electron Transfer in Sulfite-oxidizing Enzymes Is Revealed by High Resolution Structure of a Heterodimeric Complex of the Catalytic Molybdopterin Subunit and a c-Type Cytochrome Subunit
2005
The Hallmarks of Aging
2013 Standout
Catalytic promiscuity and the evolution of new enzymatic activities
1999
Site Directed Mutagenesis of Amino Acid Residues at the Active Site of Mouse Aldehyde Oxidase AOX1
2009
Nucleotide Excision Repair
2005 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Molybdenum and tungsten enzymes: the xanthine oxidase family
2006
Aryl sulfamates are broad spectrum inactivators of sulfatases: Effects on sulfatases from various sources
2008
An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair
2009 StandoutNobel
Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship
2005
Structural and Biochemical Identification of a Novel Bacterial Oxidoreductase
2004
Novel cofactors via post-translational modifications of enzyme active sites
2000
Structure of the DNA Repair Helicase XPD
2008
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase
2011
1.3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase Family
2001
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Purification and Characterization of the FeII- and α-Ketoglutarate-Dependent Xanthine Hydroxylase from Aspergillus nidulans
2007
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Direct Demonstration of the Presence of Coordinated Sulfate in the Reaction Pathway of Arabidopsis thaliana Sulfite Oxidase Using 33S Labeling and ESEEM Spectroscopy
2007
Catalytic Proficiency: The Extreme Case of S–O Cleaving Sulfatases
2011
Spectroscopic studies of molybdenum and tungsten enzymes
2011
Sulfatase Activity of E. coli Alkaline Phosphatase Demonstrates a Functional Link to Arylsulfatases, an Evolutionarily Related Enzyme Family
1998
Kinetic, Structural, and EPR Studies Reveal That Aldehyde Oxidoreductase from Desulfovibrio gigas Does Not Need a Sulfido Ligand for Catalysis and Give Evidence for a Direct Mo−C Interaction in a Biological System
2009
Directed Evolution: Bringing New Chemistry to Life
2017 StandoutNobel
New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymes in Vitro and in Vivo
2008 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Structure of a Xanthine Oxidase-Related 4-Hydroxybenzoyl-CoA Reductase with an Additional [4Fe-4S] Cluster and an Inverted Electron Flow
2004
The Reaction Mechanism of Xanthine Oxidase: Evidence for Two-Electron Chemistry Rather Than Sequential One-Electron Steps
2002
Covalent Modifiers: An Orthogonal Approach to Drug Design
2009
A mutation in T7 RNA polymerase that facilitates promoter clearance
2005
Molybdenum Site Structure of Escherichia coli YedY, a Novel Bacterial Oxidoreductase
2010
Initiation of Repair of DNA−Polypeptide Cross-Links by the UvrABC Nuclease
2005
Direct Observation of Hydrogen Bonds in Nucleic Acid Base Pairs by Internucleotide 2JNN Couplings
1998
Structural Studies of the Molybdenum Center of the Pathogenic R160Q Mutant of Human Sulfite Oxidase by Pulsed EPR Spectroscopy and 17O and 33S Labeling
2008
Structural Basis of Eukaryotic Nitrate Reduction: Crystal Structures of the Nitrate Reductase Active Site
2005
Structural aspects of mononuclear Mo/W-enzymes
2010
Identification and Characterization of a Novel Bacterial Sulfite Oxidase with No Heme Binding Domain from Deinococcus radiodurans
2005
Xanthine Dehydrogenase Electrocatalysis: Autocatalysis and Novel Activity
2011
The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria
2010
QM/MM Studies of Xanthine Oxidase: Variations of Cofactor, Substrate, and Active-Site Glu802
2010
Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages
2005
Identity of the Exchangeable Sulfur-Containing Ligand at the Mo(V) Center of R160Q Human Sulfite Oxidase
2012
Electronic Structure Description of thecis-MoOS Unit in Models for Molybdenum Hydroxylases
2007
Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology
2003
Prokaryotic Nucleotide Excision Repair: The UvrABC System
2006
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
SULFATASES AND HUMAN DISEASE
2005
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
Eukaryotic DNA Polymerases
2002
[13C,13C]- and [13C,1H]-TROSY in a Triple Resonance Experiment for Ribose−Base and Intrabase Correlations in Nucleic Acids1
2001 StandoutNobel
Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells
2013 StandoutNobel
The oxygen‐tolerant and NAD +‐dependent formate dehydrogenase from Rhodobacter capsulatus is able to catalyze the reduction of CO 2 to formate
2013
Enzymatic Mechanisms of Phosphate and Sulfate Transfer
2006
Spectroscopic Characterization of YedY: The Role of Sulfur Coordination in a Mo(V) Sulfite Oxidase Family Enzyme Form
2009
Formylglycine, a Post-Translationally Generated Residue with Unique Catalytic Capabilities and Biotechnology Applications
2014 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
The Mononuclear Molybdenum Enzymes
2014 Standout
X-ray Crystal Structure and EPR Spectra of “Arsenite-Inhibited” Desulfovibrio gigas Aldehyde Dehydrogenase: A Member of the Xanthine Oxidase Family
2004
A Combined QM/MM Study on the Reductive Half-Reaction of Xanthine Oxidase: Substrate Orientation and Mechanism
2009
Mitochondrial DNA mutations in disease and aging
2011
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Molybdenum enzymes in bacteria and their maturation
2011
Bioinorganic chemistry of molybdenum and tungsten enzymes: A structural–functional modeling approach
2010
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
MOLYBDENUM COFACTOR BIOSYNTHESIS AND MOLYBDENUM ENZYMES
2006
Structure-Based Alteration of Substrate Specificity and Catalytic Activity of Sulfite Oxidase from Sulfite Oxidation to Nitrate Reduction
2012
Spectroscopic and Kinetic Studies of Arabidopsis thaliana Sulfite Oxidase: Nature of the Redox-Active Orbital and Electronic Structure Contributions to Catalysis
2005
NMR scalar couplings across Watson–Crick base pair hydrogen bonds in DNA observed by transverse relaxation-optimized spectroscopy
1998 StandoutNobel
Evolutionary Persistence of the Molybdopyranopterin-Containing Sulfite Oxidase Protein Fold
2008
Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
2005
Direct Detection and Characterization of Chloride in the Active Site of the Low-pH Form of Sulfite Oxidase Using Electron Spin Echo Envelope Modulation Spectroscopy, Isotopic Labeling, and Density Functional Theory Calculations
2009
Identification of a Rhodobacter capsulatus l -Cysteine Desulfurase That Sulfurates the Molybdenum Cofactor When Bound to XdhC and before Its Insertion into Xanthine Dehydrogenase
2007
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Inhibition Studies of Bovine Xanthine Oxidase by Luteolin, Silibinin, Quercetin, and Curcumin
2009
Sequential Release of Promoter Contacts during Transcription Initiation to Elongation Transition
2006
Works of Karsten Theis being referenced
Determination of backbone nitrogen–nitrogen J correlations in proteins
1997
Identification of Residues within UvrB That Are Important for Efficient DNA Binding and Damage Processing
2004
Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis
2003
Crystal Structure and Deletion Analysis Show that the Accessory Subunit of Mammalian DNA Polymerase γ, PolγB, Functions as a Homodimer
2001
Crystal Structures of the Active and Alloxanthine-Inhibited Forms of Xanthine Dehydrogenase from Rhodobacter capsulatus
2002
Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair
2004
The β-Hairpin Motif of UvrB Is Essential for DNA Binding, Damage Processing, and UvrC-mediated Incisions
2002
Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair
1999
The Crystal Structure of Plant Sulfite Oxidase Provides Insights into Sulfite Oxidation in Plants and Animals
2003
Twisted or Shifted? Fluorescence Measurements of Late Intermediates in Transcription Initiation by T7 RNA Polymerase
2007
Topological and Conformational Analysis of the Initiation and Elongation Complex of T7 RNA Polymerase Suggests a New Twist
2004
Crystal Structure of Human Arylsulfatase A: The Aldehyde Function and the Metal Ion at the Active Site Suggest a Novel Mechanism for Sulfate Ester Hydrolysis,
1998
The nucleotide excision repair protein UvrB, a helicase-like enzyme with a catch
2000