Citation Impact
Citing Papers
Luminal particles within cellular microtubules
2006 StandoutNobel
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
2004
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
2003
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Roles of tau protein in health and disease
2017
The Amyloid Precursor Protein-binding Protein APP-BP1 Drives the Cell Cycle through the S-M Checkpoint and Causes Apoptosis in Neurons
2000
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
2010
Role of the Tau N-terminal region in microtubule stabilization revealed by newendogenous truncated forms
2015
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Axonal Transport RatesIn VivoAre Unaffected by Tau Deletion or Overexpression in Mice
2008
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005
Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
2009
Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial
2016
Regulation and function of the interaction between the APC tumour suppressor protein and EB1
2000
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
2012
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
2001 StandoutNobel
Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo
2006
Increased p27, an essential component of cell cycle control, in Alzheimer's disease
2003
Going new places using an old MAP: tau, microtubules and human neurodegenerative disease
2001
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
2009
Repeat motifs of tau bind to the insides of microtubules in the absence of taxol
2002
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
C-terminal ECFP Fusion Impairs Synaptotagmin 1 Function
2004 StandoutNobel
The Molecular Motor Toolbox for Intracellular Transport
2003
Alzheimer's disease
2011 Standout
Axon pathology in neurological disease: a neglected therapeutic target
2002
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity
2008
The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
2008
Amyloid‐β‐induced toxicity of primary neurons is dependent upon differentiation‐associated increases in tau and cyclin‐dependent kinase 5 expression
2003
Are Tangles as Toxic as They Look?
2011
Trafficking and Proteolytic Processing of APP
2012
Structural Principles of Tau and the Paired Helical Filaments of Alzheimer’s Disease
2007
A journey into space
2001 StandoutNobel
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
SUT-1 enables tau-induced neurotoxicity in C . elegans
2007
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship
2010
Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
2011
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
2005
Tau in physiology and pathology
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
2004
CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival
2004
Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases
2011
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
The axonal transport of mitochondria
2012
Alzheimer's disease
2006 Standout
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
2003 Standout
Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules
1999
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
2011 StandoutNobel
Post-translational modifications of tau protein in Alzheimer’s disease
2004
Alzheimer's Disease
2010 Standout
Missorting of Tau in Neurons Causes Degeneration of Synapses That Can Be Rescued by the Kinase MARK2/Par-1
2007
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Amyloid‐β oligomers induce synaptic damage via Tau‐dependent microtubule severing by TTLL6 and spastin
2013
Tau oligomers and aggregation in Alzheimer’s disease
2009
Lysosomal Activation Is a Compensatory Response Against Protein Accumulation and Associated Synaptopathogenesis—An Approach for Slowing Alzheimer Disease?
2003
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
2000
The Amyloid State of Proteins in Human Diseases
2012 Standout
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.
2000 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
2004
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
2005
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
1999 Nature
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
2005
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis
2005
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
2012
Aβ Oligomers Cause Localized Ca 2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
2010
Interaction of the G′ Domain of Elongation Factor G and the C-Terminal Domain of Ribosomal Protein L7/L12 during Translocation as Revealed by Cryo-EM
2005 StandoutNobel
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
2004
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites
2009
Molecular motors implicated in the axonal transport of tau and α-synuclein
2005
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Amyloid-β, Tau, and Dementia
2009
Structure, Microtubule Interactions, and Paired Helical Filament Aggregation by Tau Mutants of Frontotemporal Dementias
2000
Tau interaction with microtubules in vivo
2004
A Century of Alzheimer's Disease
2006 StandoutScience
Tau is essential to β-amyloid-induced neurotoxicity
2002
3D structure of Alzheimer's amyloid-β(1–42) fibrils
2005 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
GSK-3 is essential in the pathogenesis of Alzheimer's disease
2006
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Rapid dynamics of the microtubule binding of ensconsin in vivo
2001
The Slow Axonal Transport of the Microtubule-Associated Protein Tau and the Transport Rates of Different Isoforms and Mutants in Cultured Neurons
2002
Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
2007
Chemically Optimizing Operational Efficiency of Molecular Rotary Motors
2014 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Artificial Molecular Machines
2015 Standout
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Role of Tau Protein in Both Physiological and Pathological Conditions
2004
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
1999
Phosphorylation that Detaches Tau Protein from Microtubules (Ser262, Ser214) Also Protects It against Aggregation into Alzheimer Paired Helical Filaments
1999
Establishment and plasticity of neuronal polarity
1999
Protein Kinase MARK/PAR-1 Is Required for Neurite Outgrowth and Establishment of Neuronal Polarity
2002
Dendritic BC200 RNA in aging and in Alzheimer's disease
2007
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
2002
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
2012
Differential Regulation of Dynein and Kinesin Motor Proteins by Tau
2008 Science
Works of Karsten Stamer being referenced
Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models
2015
The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease
1998
Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
1998
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
2002