Citation Impact
Citing Papers
Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008
2008 Standout
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF
2001 StandoutScience
Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
2017
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
2017
Long term immunologic consequences of experimental stroke and mucosal tolerance
2009
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Harnessing hypoxic adaptation to prevent, treat, and repair stroke
2007
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Increase in Endogenous Brain Superoxide Dismutase as a Potential Mechanism of Lipopolysaccharide-Induced Brain Ischemic Tolerance
2000
Harms and benefits of lymphocyte subpopulations in patients with acute stroke
2008
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1
2000 StandoutNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Role of erythropoietin in the brain
2007
Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression
2008
Cerebral preconditioning and ischaemic tolerance
2006
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Pathobiology of ischaemic stroke: an integrated view
1999 Standout
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
2009
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Immune responses after acute ischemic stroke or myocardial infarction
2010
Central nervous system injury-induced immune deficiency syndrome
2005 Standout
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use
2009
Hypoxia and Inflammation
2011 Standout
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
In VitroIschemic Tolerance Involves Upregulation of Glutamate Transport Partly Mediated by the TACE/ADAM17-Tumor Necrosis Factor-α Pathway
2004
DNA methylation in health and disease
2000
Ischemic tolerance and endogenous neuroprotection
2003
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Hypoxic preconditioning involves system Xc− regulation in mouse neural stem cells
2011
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
2006 Nature
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
A novel endogenous erythropoietin mediated pathway prevents axonal degeneration
2004
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
2008 Standout
The immunology of stroke: from mechanisms to translation
2011 Standout
HIF–prolyl hydroxylases and cardiovascular diseases
2012
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
2002 StandoutNobel
Neural regulators of innate immune responses and inflammation
2004
Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms
2007
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke
2007
Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat
2006
Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo
2005
Molecular Physiology of Preconditioning-Induced Brain Tolerance to Ischemia
2008
Myocardial Reperfusion Injury
2007 Standout
Neuroprotection in the PNS: Erythropoietin and Immunophilin Ligands
2005
Sensitization and tolerization to brain antigens in stroke
2008
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The Inflammasomes
2010 Standout
Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α
2003 StandoutNobel
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Hypoxia-inducible Factor-1 Deficiency Results in Dysregulated Erythropoiesis Signaling and Iron Homeostasis in Mouse Development
2006 StandoutNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity
2009
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain
2009
Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism?
2002
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Hypoxia-inducible Factor Prolyl 4-Hydroxylase Inhibition
2005
ERYTHROPOIETIN ATTENUATES THE TISSUE INJURY ASSOCIATED WITH HEMORRHAGIC SHOCK AND MYOCARDIAL ISCHEMIA
2004
Brain dendritic cells in ischemic stroke: Time course, activation state, and origin
2009
Functional Status of Peripheral Blood T-Cells in Ischemic Stroke Patients
2010
Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection
2009
Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain
2000 StandoutNobel
Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-α and ceramide
2000
Hypoxia-Inducible Factor-1α Mediates Hypoxia-Induced Delayed Neuronal Death That Involves p53
1999
Preventive Antibacterial Treatment Improves the General Medical and Neurological Outcome in a Mouse Model of Stroke
2003
Normobaric Hypoxia Induces Tolerance to Focal Permanent Cerebral Ischemia in Association with an Increased Expression of Hypoxia-Inducible Factor-1 and its Target Genes, Erythropoietin and VEGF, in the Adult Mouse Brain
2002
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
Experimental Stroke-Induced Changes in the Bone Marrow Reveal Complex Regulation of Leukocyte Responses
2010
Neuroprotection by Hypoxic Preconditioning Involves Oxidative Stress-Mediated Expression of Hypoxia-Inducible Factor and Erythropoietin
2005
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Oxidative stress in glaucomatous neurodegeneration: Mechanisms and consequences
2006
Experimental Stroke Induces Massive, Rapid Activation of the Peripheral Immune System
2005
Role of T Lymphocytes and Interferon-γ in Ischemic Stroke
2006
Ischemic Tolerance
2002
Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
2003 StandoutNobel
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Targeting tumors through the HIF system
2000 StandoutNobel
Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning?
2008
Inhibition of NGF deprivation–induced death by low oxygen involves suppression of BIMEL and activation of HIF-1
2005
Infection After Acute Ischemic Stroke
2007
Inhibition of Toll-like Receptor and Cytokine Signaling—A Unifying Theme in Ischemic Tolerance
2004 StandoutNobel
HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
2010 StandoutNobel
Protection from Oxidative Stress–Induced Apoptosis in Cortical Neuronal Cultures by Iron Chelators Is Associated with Enhanced DNA Binding of Hypoxia-Inducible Factor-1 and ATF-1/CREB and Increased Expression of Glycolytic Enzymes, p21waf1/cip1, and Erythropoietin
1999 StandoutNobel
Intranasal delivery of erythropoietin plus insulin-like growth factor–I for acute neuroprotection in stroke
2009
Erythropoietin Selectively Attenuates Cytokine Production and Inflammation in Cerebral Ischemia by Targeting Neuronal Apoptosis
2003
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.
1999
Translation of Ischemic Preconditioning to the Patient
2004
T- and B-Cell-Deficient Mice with Experimental Stroke have Reduced Lesion Size and Inflammation
2007
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Recombinant T Cell Receptor Ligand Treats Experimental Stroke
2009
Works of Karsten Ruscher being referenced
Non-toxic amyloid beta formed in the presence of glypican-1 or its deaminatively generated heparan sulfate degradation products
2013
Induction of ischemic tolerance in rat cortical neurons by 3-nitropropionic acid: chemical preconditioning
1999
Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons
1998
A fluorescence based non-radioactive electrophoretic mobility shift assay
2000
Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia
2015
Induction of tolerance in rat cortical neurons: hypoxic preconditioning
1997
Respiratory Chain Inhibition Induces Tolerance to Focal Cerebral Ischemia
1999
DNA Methyltransferase Contributes to Delayed Ischemic Brain Injury
2000
Desferrioxamine Induces Delayed Tolerance against Cerebral Ischemia in Vivo and in Vitro
2002
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model.
2002
Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from anIn VitroModel
2002
Serial Analysis of Gene Expression Identifies Metallothionein-II as Major Neuroprotective Gene in Mouse Focal Cerebral Ischemia
2002
Hypoxia-Induced Stroke Tolerance in the Mouse Is Mediated by Erythropoietin
2003
Stroke-induced Immunodeficiency Promotes Spontaneous Bacterial Infections and Is Mediated by Sympathetic Activation Reversal by Poststroke T Helper Cell Type 1–like Immunostimulation
2003