Citation Impact
Citing Papers
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Identification of the haematopoietic stem cell niche and control of the niche size
2003 StandoutNature
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Retinoblastoma protein switches the E2F site from positive to negative element
1992 Nature
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
c-Myc-regulated microRNAs modulate E2F1 expression
2005 StandoutNature
Immunotherapy of Hematologic Malignancy
2003
Osteoblastic cells regulate the haematopoietic stem cell niche
2003 StandoutNature
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
1994
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Network calisthenics
2011
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1993 Standout
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
Recent advances into the understanding of mesenchymal stem cell trafficking
2007
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
The Rb/E2F pathway: expanding roles and emerging paradigms
2000 Standout
E2F target genes: unraveling the biology
2004
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Principles of CDK regulation
1995 StandoutNature
In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue
2002
Revealing the world of RNA interference
2004 StandoutNatureNobel
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.
1991
The retinoblastoma protein as a transcriptional repressor
1993
Hepatocyte growth factor is secreted by osteoblasts and cooperatively permits the survival of haematopoietic progenitors
2001
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Control of c-myc Regulation in Normal and Neoplastic Cells
1991
Wnt signalling in stem cells and cancer
2005 StandoutNature
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells
2003 StandoutNobel
Structural and functional contributions to the G1 blocking action of the retinoblastoma protein. (the 1992 Gordon Hamilton Fairley Memorial Lecture)
1993 StandoutNobel
The CBP co-activator is a histone acetyltransferase
1996 StandoutNature
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
1991
The "common stem cell" hypothesis reevaluated: human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors
1995
The Retinoblastoma Protein Binds to a Family of E2F Transcription Factors
1993
Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity
1991
Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27
1995 StandoutScience
An Essential Domain of the c-Myc Protein Interacts with a Nuclear Factor That Is Also Required for E1A-Mediated Transformation
1995
The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex.
1989
Thrombopoietin Is Synthesized by Bone Marrow Stromal Cells
1997
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Role of Members of the Wnt Gene Family in Human Hematopoiesis
1998
G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.
1993 StandoutNobel
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Association of cdk2 Kinase with the Transcription Factor E2F During S Phase
1992 Science
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.
1995
Cancer Cell Cycles
1996 StandoutScience
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase
1999
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
1993 StandoutNobel
The retinoblastoma protein binds to a family of E2F transcription factors.
1993
Role of E2F transcription factor in E1A-mediated trans activation of cellular genes
1991
A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.
1990
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors
1998 StandoutScience
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.
1995
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation.
1994
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
The Transcription Factor E2F-1 Is a Downstream Target of RB Action
1995 StandoutNobel
N-cadherin is developmentally regulated and functionally involved in early hematopoietic cell differentiation
2001
The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter
1992
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
1993
Differential regulation of E2F transactivation by cyclin/cdk2 complexes.
1994
E2F Is Required To Prevent Inappropriate S-Phase Entry of Mammalian Cells
2000
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins.
1994
Regions of the Retinoblastoma Gene Product Required for its Interaction with the E2F Transcription Factor are Necessary for E2 Promoter Repression and pRb-Mediated Growth Suppression
1993
Cyclin A/CDK2 Binds Directly to E2F-1 and Inhibits the DNA-Binding Activity of E2F-1/DP-1 by Phosphorylation
1994
Altered Cell Cycle Kinetics, Gene Expression, and G1 Restriction Point Regulation in Rb-Deficient Fibroblasts
1996
Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro.
1993
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.
1993
A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter.
1993 StandoutNobel
Cell Cycle Analysis of E2F in Primary Human T Cells Reveals Novel E2F Complexes and Biochemically Distinct Forms of Free E2F
1993
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.
1993
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily
1995 StandoutScience
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
1997
Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
1993
Multiple Changes in E2F Function and Regulation Occur upon Muscle Differentiation
1995
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.
1993
Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters
1994
Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow‐repopulating ability together with the expansion of committed progenitors
2000
CTCF, a Conserved Nuclear Factor Required for Optimal Transcriptional Activity of the Chicken c-myc Gene, Is an 11-Zn-Finger Protein Differentially Expressed in Multiple Forms
1993
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Transcription Factor E2F Is Required for Efficient Expression of the Hamster Dihydrofolate Reductase Gene In Vitro and In Vivo
1989
A Protein Synthesis-Dependent Increase in E2F1 mRNA Correlates with Growth Regulation of the Dihydrofolate Reductase Promoter
1993 StandoutNobel
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins
1992 Science
Another p53 Doppelgänger?
1998 StandoutScienceNobel
Works of Karin Thalmeier being referenced
Establishment of two permanent human bone marrow stromal cell lines with long-term post irradiation feeder capacity
1994
"Stem cell candidates" purified by liquid culture in the presence of Steel factor, IL-3, and 5FU are strictly stroma-dependent and have myeloid, lymphoid, and megakaryocytic potential.
1997
Evidence of Peripheral Blood‐Derived, Plastic‐Adherent CD34 −/low Hematopoietic Stem Cell Clones with Mesenchymal Stem Cell Characteristics
2000
Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter.
1989
Characterization of hemopoietic cell populations from human cord blood expressing c-kit.
1993
Constitutive and modulated cytokine expression in two permanent human bone marrow stromal cell lines.
1996
Graft-versus-host reaction spares normal stem cells in chronic myelogenous leukemia.
1996