Standout Papers
Citation Impact
Citing Papers
Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors
2009 Science
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Reconstitution of invertebrate glutamate receptor function depends on stargazin-like proteins
2006
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
2010 StandoutScience
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Regulation of NMDA receptors by cyclin-dependent kinase-5
2001
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Regulation of Editing and Expression of Glutamate α-Amino-Propionic-Acid (AMPA)/Kainate Receptors by Antidepressant Drugs
2006
Developmental Expression of Ca2+-Permeable AMPA Receptors Underlies Depolarization-Induced Long-Term Depression at Mossy Fiber–CA3 Pyramid Synapses
2007
Modulation of non‐NMDA receptor gating by auxiliary subunits
2014
A C-Terminal Determinant of GluR6 Kainate Receptor Trafficking
2004
A Role for Extracellular Na+in the Channel Gating of Native and Recombinant Kainate Receptors
2003
Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding
2006
External anions and cations distinguish between AMPA and kainate receptor gating mechanisms
2002
Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6
2007
A Transmembrane Accessory Subunit that Modulates Kainate-Type Glutamate Receptors
2009
Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine
2009
Domain organization and function in GluK2 subtype kainate receptors
2010
Block of Kainate Receptor Desensitization Uncovers a Key Trafficking Checkpoint
2006
Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
Genomic organization of the human GRIK2 gene and evidence for multiple splicing variants
2001
Q/R Site Editing Controls Kainate Receptor Inhibition by Membrane Fatty Acids
2005
Visualization of Subunit-Specific Delivery of Glutamate Receptors to Postsynaptic Membrane during Hippocampal Long-Term Potentiation
2012
An Endoplasmic Reticulum Retention Signal Located in the Extracellular Amino-terminal Domain of the NR2A Subunit of N-Methyl-d-aspartate Receptors
2009
Glutamate Receptor Trafficking: Endoplasmic Reticulum Quality Control Involves Ligand Binding and Receptor Function
2005
Crystal Structures of the Kainate Receptor GluR5 Ligand Binding Core Dimer with Novel GluR5-Selective Antagonists
2006
Amino-Acid Residues Involved in Glutamate Receptor 6 Kainate Receptor Gating and Desensitization
2003
Amino acid substitutions in the pore of rat glutamate receptors at sites influencing block by polyamines
1999
Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders
2000
Ionotropic Glutamate Receptors & CNS Disorders
2008
The Serine Protease Plasmin Cleaves the Amino-terminal Domain of the NR2A Subunit to Relieve Zinc Inhibition of the N-Methyl-d-aspartate Receptors
2009
A Nondesensitizing Kainate Receptor Point Mutant
2009
Intracellular Domains of NR2 Alter Calcium-Dependent Inactivation of N-Methyl-d-aspartate Receptors
2002
Structure–activity analysis of a novel NR2C/NR2D‐preferring NMDA receptor antagonist: 1‐(phenanthrene‐2‐carbonyl) piperazine‐2,3‐dicarboxylic acid
2004
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
2008
Binding of spermine and ifenprodil to a purified, soluble regulatory domain of theN‐methyl‐d‐aspartate receptor
2008
Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation
2009
Glutamate receptor ion channels
2005 Standout
Analysis of Transcriptional Regulatory Sequences of the N-Methyl-d-aspartate Receptor 2A Subunit Gene in Cultured Cortical Neurons and Transgenic Mice
2002
N-Methyl-d-aspartate (NMDA) Receptor Subunit NR1 Forms the Substrate for Oligomeric Assembly of the NMDA Receptor
2007
Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum
2008
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Mammalian polyamine metabolism and function
2009
Understanding Synapses: Past, Present, and Future
2008 StandoutNobel
Stargazin Reduces Desensitization and Slows Deactivation of the AMPA-Type Glutamate Receptors
2005
Protons Trap NR1/NR2B NMDA Receptors in a Nonconducting State
2005
Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines
2010 StandoutNobel
Amyloid beta peptides and glutamatergic synaptic dysregulation
2007
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
NMDA receptors in clinical neurology: excitatory times ahead
2008
Molecular Architecture of the Mouse Nervous System
2018 Standout
Pilocarpine-Induced Seizures Cause Selective Time-Dependent Changes to Adult-Generated Hippocampal Dentate Granule Cells
2007
Staggering of Subunits in NMDAR Channels
2002
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
2005 Nature
Structural aspects of AMPA receptor activation, desensitization and deactivation
2007
Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed inXenopus laevisoocytes
2007
3-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists
2006
Pharmacological characterization, localization, and regulation of ionotropic glutamate receptors in skate horizontal cells
2009
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Gating Reaction Mechanisms for NMDA Receptor Channels
2005
Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor
2006
The Stoichiometry of AMPA Receptors and TARPs Varies by Neuronal Cell Type
2009
Modulation of the Dimer Interface at Ionotropic Glutamate-Like Receptor δ2 by d-Serine and Extracellular Calcium
2009
Glutamate uptake
2001 Standout
The Interaction between Stargazin and PSD-95 Regulates AMPA Receptor Surface Trafficking
2007
Astrocytic control of synaptic NMDA receptors
2007
20-Oxo-5β-Pregnan-3α-yl Sulfate Is a Use-Dependent NMDA Receptor Inhibitor
2005
A Splice Code for trans-Synaptic Cell Adhesion Mediated by Binding of Neuroligin 1 to α- and β-Neurexins
2005 StandoutNobel
Neuroprotection by the NR3A Subunit of the NMDA Receptor
2009
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
AMPA Receptor Trafficking at Excitatory Synapses
2003
Interaction of the M4 Segment with Other Transmembrane Segments Is Required for Surface Expression of Mammalian α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors
2011
The Quaternary Structure of a Calcium-Permeable AMPA Receptor: Conservation of Shape and Symmetry across Functionally Distinct Subunit Assemblies
2008
AMPA Receptor Binding Cleft Mutations That Alter Affinity, Efficacy, and Recovery from Desensitization
2005
Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core
2002
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
2005
The Transmembrane Domain Mediates Tetramerization of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors
2016
Identification of a Site in GluR1 and GluR2 That Is Important for Modulation of Deactivation and Desensitization
2003
The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain
2007
Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
2005
Regulation of mitogen‐activated protein kinases by glutamate receptors
2006
Characterization of the Binding Site for a Novel Class of Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Antagonists
2000
Regulatory mechanisms of AMPA receptors in synaptic plasticity
2007
Activation of recombinant NR1/NR2C NMDA receptors
2008
Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor
2000
Pharmacology of δ2 Glutamate Receptors: Effects of Pentamidine and Protons
2003
Structural Features of the Glutamate Binding Site in Recombinant NR1/NR2A N-Methyl-D-aspartate Receptors Determined by Site-Directed Mutagenesis and Molecular Modeling
2005
Pharmacological Characterization of Glycine-Activated Currents in HEK 293 Cells Expressing N-Methyl-D-aspartate NR1 and NR3 Subunits
2007
Two Families of TARP Isoforms that Have Distinct Effects on the Kinetic Properties of AMPA Receptors and Synaptic Currents
2007
Permeant Ion Effects on External Mg2+Block of NR1/2D NMDA Receptors
2006
Relating NMDA Receptor Function to Receptor Subunit Composition: Limitations of the Pharmacological Approach
2006
Azobenzene Photoswitches for Staudinger–Bertozzi Ligation
2013 StandoutNobel
Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential
2009
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Changes in Agonist Concentration Dependence That Are a Function of Duration of Exposure SuggestN-Methyl-d-aspartate Receptor Nonsaturation during Synaptic Stimulation
2001
LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
2013 StandoutNobel
Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
2005
Stereocontrolled Synthesis and Pharmacological Evaluation of Azetidine‐2,3‐Dicarboxylic Acids at NMDA Receptors
2008
Organic blockers escape from trapping in the AMPA receptor channels by leaking into the cytoplasm
2007
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-d-aspartate receptors
2009
Characterization of the Rat GRIK5 Kainate Receptor Subunit Gene Promoter and Its Intragenic Regions Involved in Neural Cell Specificity
2001
Xenopus laevis Oocytes Endogenously Express All Subunits of the Ionotropic Glutamate Receptor Family
2009
Block of AMPA Receptor Desensitization by a Point Mutation outside the Ligand-Binding Domain
2004
Interdomain Interactions in AMPA and Kainate Receptors Regulate Affinity for Glutamate
2006
Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1β Complex Reveal Specific Protein-Protein and Protein-Ca2+ Interactions
2007 StandoutNobel
Why glycine transporters have different stoichiometries
2002
Structure and function of an irreversible agonist-β2 adrenoceptor complex
2011 StandoutNatureNobel
Coupling of Energy Metabolism and Synaptic Transmission at the Transcriptional Level: Role of Nuclear Respiratory Factor 1 in Regulating both CytochromecOxidase and NMDA Glutamate Receptor Subunit Genes
2009
Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression
2004
Nuclear respiratory factor 1 co‐regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy metabolism in neurons
2009
Allosteric control of an ionotropic glutamate receptor with an optical switch
2005
Revisiting the Postulated “Unitary Glutamate Receptor”: Electrophysiological and Pharmacological Analysis in Two Heterologous Expression Systems Fails to Detect Evidence for Its Existence
2005
Structural Rearrangements of NR1/NR2A NMDA Receptors during Allosteric Inhibition
2008
Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus
2005
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
NMDA receptor function: subunit composition versus spatial distribution
2006
Extracellular Interactions between GluR2 and N-Cadherin in Spine Regulation
2007
The chemical biology of clinically tolerated NMDA receptor antagonists
2006
Crystal structure and association behaviour of the GluR2 amino‐terminal domain
2009
PICK1 and Phosphorylation of the Glutamate Receptor 2 (GluR2) AMPA Receptor Subunit Regulates GluR2 Recycling after NMDA Receptor-Induced Internalization
2007
NMDA Receptor NR2 Subunit Dependence of the Slow Component of Magnesium Unblock
2006
Structural landscape of isolated agonist-binding domains from single AMPA receptors
2011
Dissection of Synapse Induction by Neuroligins
2005 StandoutNobel
Four Different Subunits Are Essential for Expressing the Synaptic Glutamate Receptor at Neuromuscular Junctions ofDrosophila
2005
Amantadine Inhibits NMDA Receptors by Accelerating Channel Closure during Channel Block
2005
Neuroligins Determine Synapse Maturation and Function
2006 StandoutNobel
A Novel Conus Snail Polypeptide Causes Excitotoxicity by Blocking Desensitization of AMPA Receptors
2009
Developmental Changes in AMPA and Kainate Receptor-Mediated Quantal Transmission at Thalamocortical Synapses in the Barrel Cortex
2005
Apparent Homomeric NR1 Currents Observed in Xenopus Oocytes are Caused by an Endogenous NR2 Subunit
2007
Mg2+Imparts NMDA Receptor Subtype Selectivity to the Alzheimer's Drug Memantine
2009
Molecular Determinants of Glycine-Independent Desensitization of NR1/NR2A Receptors
2005
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
2005 Nature
Mechanism of Positive Allosteric Modulators Acting on AMPA Receptors
2005
The Activation Gate and Gating Mechanism of the NMDA Receptor
2008
Desensitization of NMDA Receptor Channels Is Modulated by Glutamate Agonists
2001
Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases
2013
Competitive AMPA receptor antagonists
2006
Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits
2005
Site within N-Methyl-D-aspartate Receptor Pore Modulates Channel Gating
2004
Sequence and analysis of the 5′ flanking and 5′ untranslated regions of the rat N-methyl-d-aspartate receptor 2A gene
2002
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Memantine binding to a superficial site on NMDA receptors contributes to partial trapping
2009
Identification of Tbr‐1/CASK complex target genes in neurons
2004
Crystal Structure of the GluR2 Amino-Terminal Domain Provides Insights into the Architecture and Assembly of Ionotropic Glutamate Receptors
2009
Differential binding properties of [3H]dextrorphan and [3H]MK-801 in heterologously expressed NMDA receptors
2005
Translational regulation of GluR2 mRNAs in rat hippocampus by alternative 3′ untranslated regions
2009
Molecular Dynamics Simulations of the Ligand-Binding Domain of the Ionotropic Glutamate Receptor GluR2
2002
Enhancement of NMDA receptor‐mediated currents by light in rat neurones in vitro
2000
Different Domains of the AMPA Receptor Direct Stargazin-mediated Trafficking and Stargazin-mediated Modulation of Kinetics
2006
The Selective Activation of the Glutamate Receptor GluR5 by ATPA Is Controlled by Serine 741
2003
Mechanisms of Modal Activation of GluA3 Receptors
2011
Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP
2012 StandoutNobel
Control of Glutamate Receptor 2 (GluR2) Translational Initiation by Its Alternative 3′ Untranslated Regions
2009
Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog
2005
The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity
2007
Neto1 Is a Novel CUB-Domain NMDA Receptor–Interacting Protein Required for Synaptic Plasticity and Learning
2009
An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder
2008
Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2
2005
Molecular Mechanism of AMPA Receptor Noncompetitive Antagonism
2005
Subtype-dependence of N-methyl-d-aspartate receptor modulation by pregnenolone sulfate
2005
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
Differential Regulation of Ionotropic Glutamate Receptors
2006
Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins
2006
Two mechanisms of action of the adamantane derivative IEM‐1460 at human AMPA‐type glutamate receptors
2005
Leucine-Rich Repeat Transmembrane Proteins Are Essential for Maintenance of Long-Term Potentiation
2013 StandoutNobel
Structure of the zinc‐bound amino‐terminal domain of the NMDA receptor NR2B subunit
2009
Subtypes of NMDA receptors in new‐born rat hippocampal granule cells
2002
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Subunit-Specific Agonist Activity at NR2A-, NR2B-, NR2C-, and NR2D-Containing N-Methyl-d-aspartate Glutamate Receptors
2007
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
2003
Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape ‘superslow’ afterburst EPSC in rat hippocampus
2004
Autoinactivation of Neuronal AMPA Receptors via Glutamate-Regulated TARP Interaction
2009
Major Depressive Disorder
2008 Standout
Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
2009
Fast and Slow Voltage-Dependent Dynamics of Magnesium Block in the NMDA Receptor: The Asymmetric Trapping Block Model
2004
The Free Energy Landscapes Governing Conformational Changes in a Glutamate Receptor Ligand-Binding Domain
2007
Comparative Studies of Anthraquinone- and Anthracene-Tetraamines as Blockers of N-Methyl-d-aspartate Receptors
2006
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Insights into social insects from the genome of the honeybee Apis mellifera
2006 StandoutNature
Dual Palmitoylation of NR2 Subunits Regulates NMDA Receptor Trafficking
2009
Structural and Single-Channel Results Indicate That the Rates of Ligand Binding Domain Closing and Opening Directly Impact AMPA Receptor Gating
2008
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Structural Determinants of d-Cycloserine Efficacy at the NR1/NR2C NMDA Receptors
2010
Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons
2008
Mechanism of differential control of NMDA receptor activity by NR2 subunits
2009 Nature
On the role of NR3A in human NMDA receptors
2007
Proteolysis of the N-Methyl-d-Aspartate Receptor by Calpain in Situ
2002
Interaction of hydrogen sulfide with ion channels
2010
Kainate receptors
2006
Zinc inhibition of rat NR1/NR2AN‐methyl‐d ‐aspartate receptors
2007
Partial Agonism and Antagonism of the Ionotropic Glutamate Receptor iGLuR5
2007
Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission
2006
The Role of Intracellular Sodium in the Regulation of NMDA-Receptor-Mediated Channel Activity and Toxicity
2005
The involvement of the NMDA receptor d-serine/glycine site in the pathophysiology and treatment of schizophrenia
2009
Modulation by permeant ions of Mg2+ inhibition of NMDA‐activated whole‐cell currents in rat cortical neurons
2002
Generation of neuronal variability and complexity
2006 Nature
Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
2008
NMDA Receptors Mediate Olfactory Learning and Memory in Drosophila
2005
Molecular Dynamics Simulations of the Ligand-binding Domain of an N-Methyl-d-aspartate Receptor
2006
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
2009 Nature
Structure and function of AMPA receptors
2003
Stargazin Modulation of AMPA Receptors
2016
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Tumor Necrosis Factor α Increases Neuronal Vulnerability to Excitotoxic Necrosis by Inducing Expression of the AMPA–Glutamate Receptor Subunit GluR1 via an Acid Sphingomyelinase- and NF-κB-Dependent Mechanism
2002
Subunit‐specific mechanisms and proton sensitivity of NMDA receptor channel block
2007
Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors
2005
The Structure of a Mixed GluR2 Ligand-binding Core Dimer in Complex with (S)-Glutamate and the Antagonist (S)-NS1209
2006
Evolutionary Conserved Role for TARPs in the Gating of Glutamate Receptors and Tuning of Synaptic Function
2008
Modeling of the Pore Domain of the GLUR1 Channel: Homology with K+ Channel and Binding of Channel Blockers
2002
The Relationship between Agonist Potency and AMPA Receptor Kinetics
2006
Activity Patterns Govern Synapse-Specific AMPA Receptor Trafficking between Deliverable and Synaptic Pools
2009
NR3A Modulates the Outer Vestibule of the “NMDA” Receptor Channel
2006
Extracellular Vestibule Determinants of Ca2+ Influx in Ca2+‐Permeable AMPA Receptor Channels
2003
Molecular Determinants of Proton-Sensitive N-Methyl-d-aspartate Receptor Gating
2003
Subcellular segregation of distinct heteromeric NMDA glutamate receptors in the striatum
2003
News on glutamate receptors in glial cells
1996
Developmental Changes in NMDA Neurotoxicity Reflect Developmental Changes in Subunit Composition of NMDA Receptors
2006
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
2016
Light‐Induced Control of Protein Translocation by the SecYEG Complex
2010 StandoutNobel
pH-Dependent Inhibition of Kainate Receptors by Zinc
2008
Pharmacological Implications of Two Distinct Mechanisms of Interaction of Memantine with N-Methyl-d-aspartate-Gated Channels
2005
Developmental changes in synaptic AMPA and NMDA receptor distribution and AMPA receptor subunit composition in living hippocampal neurons.
2000
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Distinct Synaptic and Extrasynaptic NMDA Receptors in Developing Cerebellar Granule Neurons
1999
Mapping the Binding Site of the Neuroprotectant Ifenprodil on NMDA Receptors
2002
Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2
2005
Specific Assembly with the NMDA Receptor 3B Subunit Controls Surface Expression and Calcium Permeability of NMDA Receptors
2003
Assembly with the NR1 Subunit Is Required for Surface Expression of NR3A-Containing NMDA Receptors
2001
NR2B and NR2D Subunits Coassemble in Cerebellar Golgi Cells to Form a Distinct NMDA Receptor Subtype Restricted to Extrasynaptic Sites
2003
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Auxiliary proteins promote modal gating ofAMPA ‐ and kainate‐type glutamate receptors
2014
Surface Expression of GluR-D AMPA Receptor Is Dependent on an Interaction between Its C-Terminal Domain and a 4.1 Protein
2003
Selective Activation Induced Cleavage of the NR2B Subunit by Calpain
2003
Synapse-Associated Protein 97 Selectively Associates with a Subset of AMPA Receptors Early in their Biosynthetic Pathway
2001
Direct and Versatile Synthesis of Red‐Shifted Azobenzenes
2016 StandoutNobel
Subunit-specific Contribution of Pore-forming Domains to NMDA Receptor Channel Structure and Gating
2007
Amino Acid Substitutions in the Pore Helix of GluR6 Control Inhibition by Membrane Fatty Acids
2008
A steroid modulatory domain on NR2B controlsN-methyl-d -aspartate receptor proton sensitivity
2004
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
The role of AMPA receptor-mediated excitotoxicity in ALS: Is deficient RNA editing to blame?
2009
Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase
2000
Conserved SOL-1 proteins regulate ionotropic glutamate receptor desensitization
2006
The Cell Biology of Synaptic Plasticity: AMPA Receptor Trafficking
2007
Conantokin-Br fromConus brettinghamiand Selectivity Determinants for the NR2D Subunit of the NMDA Receptor
2009
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Functional Characterization of Tet-AMPA [Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic Acid] Analogues at Ionotropic Glutamate Receptors GluR1−GluR4. The Molecular Basis for the Functional Selectivity Profile of 2-Bn-Tet-AMPA
2007
Multiple Molecular Determinants for Allosteric Modulation of Alternatively Spliced AMPA Receptors
2003
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Rapid Synthesis and Synaptic Insertion of GluR2 for mGluR-LTD in the Ventral Tegmental Area
2007 Science
Functional Insights from Glutamate Receptor Ion Channel Structures
2012
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Developmental Profile of the Changing Properties of NMDA Receptors at Cerebellar Mossy Fiber–Granule Cell Synapses
2000
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Studies of NMDA Receptor Function and Stoichiometry with Truncated and Tandem Subunits
2003
Subunit Interactions and AMPA Receptor Desensitization
2001
Three Pairs of Cysteine Residues Mediate Both Redox and Zn2+Modulation of the NMDA Receptor
2001
Transcription of the chickenGrin1gene is regulated by the activity of SP3 and NRSF in undifferentiated cells and neurons
2008
Channel-Lining Residues of the AMPA Receptor M2 Segment: Structural Environment of the Q/R Site and Identification of the Selectivity Filter
2001 Nobel
Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists
2008
Characterization of the Binding Site for a Novel Class of Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Antagonists
2000
A Subtype-Selective, Use-Dependent Inhibitor of Native AMPA Receptors
2007
Developmental Changes in Synaptic AMPA and NMDA Receptor Distribution and AMPA Receptor Subunit Composition in Living Hippocampal Neurons
2000
Enantiomeric Propanolamines as selectiveN-Methyl-d -aspartate 2B Receptor Antagonists
2008
Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductase
2011 StandoutNobel
N-Hydroxypyrazolyl Glycine Derivatives as SelectiveN-Methyl-d -aspartic Acid Receptor Ligands
2008
Emerging Targets in Photopharmacology
2016 StandoutNobel
Postsynaptic glutamate receptor δ family contributes to presynaptic terminal differentiation and establishment of synaptic transmission
2009
Functional Excitatory Synapses in HEK293 Cells Expressing Neuroligin and Glutamate Receptors
2003
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Cutting Edge: Granzyme B Proteolysis of a Neuronal Glutamate Receptor Generates an Autoantigen and Is Modulated by Glycosylation
2001
DRPEER: A Motif in the Extracellular Vestibule Conferring High Ca2+Flux Rates in NMDA Receptor Channels
2002
Glutamate Receptor Subunit 2 Serine 880 Phosphorylation Modulates Synaptic Transmission and Mediates Plasticity in CA1 Pyramidal Cells
2003
Molecular determinants of coordinated proton and zinc inhibition of N- methyl- d -aspartate NR1/NR2A receptors
2000
Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes
2003
GluR3 Flip and Flop: Differences in Channel Opening Kinetics
2007
Probing of NMDA Channels with Fast Blockers
1999
Identification of Amino Acid Residues in GluR1 Responsible for Ligand Binding and Desensitization
2001
Subtype-Dependence of NMDA Receptor Channel Open Probability
1999
SOL-1 is an auxiliary subunit that modulates the gating of GLR-1 glutamate receptors inCaenorhabditis elegans
2006
Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid
2005
Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors
2008
A Tetrazolyl-Substituted Subtype-Selective AMPA Receptor Agonist
2007
Mechanisms of Antagonism of the GluR2 AMPA Receptor: Structure and Dynamics of the Complex of Two Willardiine Antagonists with the Glutamate Binding Domain
2009
Works of Karin Borges being referenced
Blockade of K+ channels induced by AMPA/kainate receptor activation in mouse oligodendrocyte precursor cells is mediated by NA+ entry
1995
Chapter 11 AMPA receptors: Molecular and functional diversity
1998
Activity of the rat GluR4 promoter in transfected cortical neurons and glia
2003
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model
2003
Functional Organization of the GluR1 Glutamate Receptor Promoter
2001
GENETIC REGULATION OF GLUTAMATE RECEPTOR ION CHANNELS
1999
The Glutamate Receptor Ion Channels
1999 Standout
The glutamate receptor ion channels.
1999