Citation Impact
Citing Papers
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Tumor-Driven Paracrine Platelet-Derived Growth Factor Receptor α Signaling Is a Key Determinant of Stromal Cell Recruitment in a Model of Human Lung Carcinoma
2006
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.
2001
Hallmarks of Cancer: The Next Generation
2011 Standout
In Fibroblasts Vegf-D Expression Is Induced by Cell-Cell Contact Mediated by Cadherin-11
2001
Tissue plasminogen activator is a potent activator of PDGF‐CC
2004
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
2008
Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers
1999
Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase and phospholipase Cγ signaling pathways
2000
The PDGF family: four gene products form five dimeric isoforms
2004
PDGF-C Induces Maturation of Blood Vessels in a Model of Glioblastoma and Attenuates the Response to Anti-VEGF Treatment
2009
Lymphangiogenesis and cancer metastasis
2002 Standout
Lymphangiogenesis and tumor metastasis
2003
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Current biology of VEGF-B and VEGF-C
1999
Molecular mechanisms of lymphangiogenesis in health and disease
2002
Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis
2001
PDGF signaling in cells and mice
2004
Concurrent Induction of Lymphangiogenesis, Angiogenesis, and Macrophage Recruitment by Vascular Endothelial Growth Factor-C in Melanoma
2001
VEGF‐C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF‐7 tumors
2002
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Placenta Growth Factor and Vascular Endothelial Growth Factor B and C Expression in Microvascular Endothelial Cells and Pericytes
1999
Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development
2006
Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)
2001
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
2001 Standout
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
A Fully Human Monoclonal Antibody (CR002) Identifies PDGF-D as a Novel Mediator of Mesangioproliferative Glomerulonephritis
2003
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
2001
Cancer Metastasis: Building a Framework
2006 Standout
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
2001
The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation
2004
Clinical significance of vascular endothelial growth factor‐C (VEGF‐C) in breast cancer
2001
Ranibizumab for Neovascular Age-Related Macular Degeneration
2006 Standout
New insights into nNOS regulation of vascular homeostasis
2005 StandoutNobel
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancer
2006 Standout
Insight into the physiological functions of PDGF through genetic studies in mice
2004
VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer
1999
Purification and refolding of vascular endothelial growth factor‐B
2000
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
2002
Vascular Endothelial Growth Factor and Angiogenesis
2004 Standout
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1
2006 StandoutNobel
The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis
2000
The biology of VEGF and its receptors
2003 Standout
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Crosstalk Coregulation Mechanisms of G Protein-Coupled Receptors and Receptor Tyrosine Kinases
2006
Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
2014 Standout
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Platelet-derived growth factor A (pdgf-a) expression during zebrafish embryonic development
2002
Response to Imatinib Mesylate in Patients with Chronic Myeloproliferative Diseases with Rearrangements of the Platelet-Derived Growth Factor Receptor Beta
2002
Lymphangiogenesis in development and human disease
2005 StandoutNature
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Regulation of PDGF and its receptors in fibrotic diseases
2004
Effect of Angiogenic and Antiangiogenic Compounds on the Outgrowth of Capillary Structures from Fetal Mouse Bone Explants
2001
VEGF receptor signalling ? in control of vascular function
2006 Standout
PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment
2009
Pro-fibrogenic potential of PDGF-D in liver fibrosis
2007
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis
2001
The Role of Platelet-Derived Growth Factor Signaling in Healing Myocardial Infarcts
2006
Targeting Vascular Endothelial Growth Factor (VEGF) for Anti-tumor Therapy, by Anti-VEGF Neutralizing Monoclonal Antibodies or by VEGF Receptor Tyrosine-kinase Inhibitors
1999
Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
2013
Angiogenesis in life, disease and medicine
2005 StandoutNature
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
2003 Standout
Novel VEGF family members: VEGF-B, VEGF-C and VEGF-D
2001
Structural and functional specificities of PDGF‐C and PDGF‐D, the novel members of the platelet‐derived growth factors family
2005
Identification and expansion of human colon-cancer-initiating cells
2006 StandoutNature
Differential Binding of Vascular Endothelial Growth Factor B Splice and Proteolytic Isoforms to Neuropilin-1
1999
Structural organization of the tight junctions
2007
Vascular Endothelial Growth Factor Family and Receptor Expression in Human Choroidal Neovascular Membranes
2002
PDGF‐a/PDGF alpha‐receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis
2001
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Platelet-derived Growth Factor D, Tissue-specific Expression in the Eye, and a Key Role in Control of Lens Epithelial Cell Proliferation
2004
Emerging Biological Principles of Metastasis
2017 Standout
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Expression of Vascular Endothelial Growth Factor (VEGF) Family Members in Breast Cancer
1999
Overexpression of Lymphangiogenic Growth Factor VEGF-C in Human Pancreatic Cancer
2001
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Platelet‐derived growth factor signaling as a cue of the epithelial–mesenchymal interaction required for anuran skin metamorphosis
2003
Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting
2008
Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas
2001
The role of VEGF in normal and neoplastic hematopoiesis
2002
Effect of VEGF receptor inhibitor PTK787/ZK222548 combined with ionizing radiation on endothelial cells and tumour growth
2001
Characterization of the Interactome of the Human MutL Homologues MLH1, PMS1, and PMS2
2006
The Two PDGF Receptors Maintain Conserved Signaling In Vivo despite Divergent Embryological Functions
2001
PDGF and cardiovascular disease
2004
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
2003
PDGF-D, a new protease-activated growth factor
2001
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
2007 StandoutNobel
Vascular endothelial growth factor–C gene expression in papillary and follicular thyroid carcinomas
1999
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
2001
Cooperation between the PDGF receptors in cardiac neural crest cell migration
2007
Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells
2008
Mechanisms of Bone Metastasis
2004 Standout
Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation
2004
Reversal of experimental pulmonary hypertension by PDGF inhibition
2005
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
2004 Standout
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Vascular endothelial growth factor B controls endothelial fatty acid uptake
2010 Nature
PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor
2001
VEGF: an update on biological and therapeutic aspects
2000
Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines
2005
VEGF-A, VEGF-C, and VEGF-D in Colorectal Cancer Progression
2001
Blockade of Platelet-Derived Growth Factor or Its Receptors Transiently Delays but Does Not Prevent Fibrous Cap Formation in ApoE Null Mice
2002
Angiogenesis as a therapeutic target
2005 StandoutNature
Developmental and Pathological Angiogenesis
2011
VEGF‐null cells require PDGFR α signaling‐mediated stromal fibroblast recruitment for tumorigenesis
2004
Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues
2000
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
2008
Modeling Development and Disease with Organoids
2016 Standout
VEGFs, receptors and angiogenesis
1999
Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells
1999
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
Platelet-Derived Growth Factor Receptor-α in Ventricular Zone Cells and in Developing Neurons
2001
Spectrum of Activity and Mechanism of Action of VEGF/PDGF Inhibitors
2007
A specific requirement for PDGF-C in palate formation and PDGFR-α signaling
2004
Guidance of mesoderm cell migration in theXenopusgastrula requires PDGF signaling
2004
Monitoring Metastatic Behavior of Human Tumor Cells in Mice with Species-Specific Polymerase Chain Reaction: Elevated Expression of Angiogenesis and Bone Resorption Stimulators by Breast Cancer in Bone Metastases
2001
Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1
1999
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
2004 Standout
VEGF and its receptors
2004
Platelet-Derived Growth Factor Production by B16 Melanoma Cells Leads to Increased Pericyte Abundance in Tumors and an Associated Increase in Tumor Growth Rate
2004
Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma.
2000
Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics
2002 StandoutScience
Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.
2001
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.
2001
Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.
2000
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
2005
Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation
2010
Mice Lacking the Vascular Endothelial Growth Factor-B Gene ( Vegfb ) Have Smaller Hearts, Dysfunctional Coronary Vasculature, and Impaired Recovery From Cardiac Ischemia
2000
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
2005 Standout
Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3
1998 Science
High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas.
2000
Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities
2004
VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells
2002
Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and Proliferation of Vascular Smooth Muscle Cells in Heart-Specific Transgenic Mice
2005
Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase
2004
Roles of PDGF in animal development
2003
Mechanisms of Vessel Branching
2009
Angiogenesis in Ischemic Disease
1999
Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
2001
Neuropilin‐1 expression by tumor cells promotes tumor angiogenesis and progression
2000
VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues
2000
Cancer Genome Landscapes
2013 StandoutScience
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.
2002
Angiogenesis stimulated by PDGF‐CC, a novel member in the PDGF family, involves activation of PDGFR‐aa and ‐ap receptors
2002
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Abnormal gastrointestinal development in PDGF-A and PDGFR-α deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis
2000
The Effect of Platelet-Derived Growth Factor Ligands in Rat Cardiac Allograft Vasculopathy and Fibrosis
2006
Vascular Endothelial Growth Factor A (VEGF-A) Is Involved in Guidance of VEGF Receptor-Positive Cells to the Anterior Portion of Early Embryos
2004
Regulation of angiogenesis via vascular endothelial growth factor receptors.
2000
Early myotome specification regulates PDGFA expression and axial skeleton development
2000
Vascular Endothelial Growth Factor-B Promotes In Vivo Angiogenesis
2003
Angiogenesis in Endocrine Tumors
2003
Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis
2004
The splice variants of vascular endothelial growth factor (VEGF) and their receptors
2001
Loss of T-Cell Protein Tyrosine Phosphatase Induces Recycling of the Platelet-derived Growth Factor (PDGF) β-Receptor but Not the PDGF α-Receptor
2006
Lymphatic Vessels as Targets of Tumor Therapy?
2001
Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice
2001
VEGF-D Is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered Into Skeletal Muscle via Adenoviruses
2003
Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells
2005
Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators
2005
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates
2014
Works of Karin Aase being referenced
VEGF-B binds to VEGFR-1 and regulates plasminogen activator activity in endothelial cells
1998
Expression of a Novel PDGF Isoform, PDGF-C, in Normal and Diseased Rat Kidney
2002
Angiomotin regulates endothelial cell migration during embryonic angiogenesis
2007
Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors
1998
Angiomotin Regulates Endothelial Cell-Cell Junctions and Cell Motility
2005
Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains
2002
Expression analysis of PDGF-C in adult and developing mouse tissues
2002
PDGF-C is a new protease-activated ligand for the PDGF α-receptor
2000
Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature
1999
p130‐Angiomotin associates to actin and controls endothelial cell shape
2006
Isoform-specific Expression of VEGF-B in Normal Tissues and Tumors
2001
Transgenic Overexpression of Platelet-Derived Growth Factor-C in the Mouse Heart Induces Cardiac Fibrosis, Hypertrophy, and Dilated Cardiomyopathy
2003
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
1998
The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells
2008
Vascular Endothelial Growth Factor-B–Deficient Mice Display an Atrial Conduction Defect
2001