Citation Impact
Citing Papers
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers
2018 StandoutNobel
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
2009 StandoutNobel
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
2013 StandoutNobel
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success
2004
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
2011
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
T cell exhaustion
2011 Standout
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family
2016
Genetic susceptibility to type 1 diabetes
2005
Etiology of Type 1 Diabetes
2010
Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency
2015
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Intrinsic and extrinsic control of peripheral T‐cell tolerance by costimulatory molecules of the CD28/ B7 family
2011
The Vertebrate Genome Annotation (Vega) database
2004
Genetics, pathogenesis and clinical interventions in type 1 diabetes
2010 Nature
Tolerance and Autoimmunity: Lessons at the Bedside of Primary Immunodeficiencies
2007
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 StandoutNobel
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Pre-eclampsia
2005 Standout
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection
2015
CTLA4 gene polymorphism and autoimmunity
2005
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage φ29
2004 StandoutNobel
The Stages of Type 1A Diabetes
2005
Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes
2008
Type 1 diabetes
2013 Standout
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells
2007
Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing
2009
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Next Generation Sequencing Analysis of Human Platelet PolyA+ mRNAs and rRNA-Depleted Total RNA
2013 StandoutNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Molecular and cellular insights into T cell exhaustion
2015 Standout
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
2011 StandoutNature
Pre-eclampsia
2015 Standout
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
The vertebrate genome annotation (Vega) database
2007
The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes
2004
Latest Advances in Understanding Preeclampsia
2005 StandoutScience
The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency
2009
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
Regulatory T Cells and Human Disease
2020 StandoutNobel
B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells
2012 StandoutNobel
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
Altered phenotype and function of dendritic cells in children with type 1 diabetes
2005
Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo
2006
CTLA-4 blockade in tumor models: an overview of preclinical and translational research.
2013
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Modeling CTLA4 -linked autoimmunity with RNA interference in mice
2006
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
The Idd4 Locus Displays Sex-Specific Epistatic Effects on Type 1 Diabetes Susceptibility in Nonobese Diabetic Mice
2006
A system for Cre-regulated RNA interference in vivo
2008
A Transendocytosis Model of CTLA-4 Function Predicts Its Suppressive Behavior on Regulatory T Cells
2015
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function
2011
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Sex-Specific Effect of Insulin-Dependent Diabetes 4 on Regulation of Diabetes Pathogenesis in the Nonobese Diabetic Mouse
2005
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
2011
Cutting Edge: Chronic Inflammatory Liver Disease in Mice Expressing a CD28-Specific Ligand
2012 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells
2009
Comprehensive human genome amplification using multiple displacement amplification
2002
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans
2012 StandoutNobel
Slc11a1, Formerly Nramp1, Is Expressed in Dendritic Cells and Influences Major Histocompatibility Complex Class II Expression and Antigen-Presenting Cell Function
2007
PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes–Associated Allele Is Not a Loss-of-Function Variant
2012
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Kara Hunter being referenced
Genetic Evidence That the Differential Expression of the Ligand-Independent Isoform of CTLA-4 Is the Molecular Basis of the Idd5.1 Type 1 Diabetes Region in Nonobese Diabetic Mice
2009
Interactions between Idd5.1/Ctla4 and Other Type 1 Diabetes Genes
2007
Type 1 diabetes genes and pathways shared by humans and NOD mice
2005
HLA class II typing of whole genome amplified mouth swab DNA
2000
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes
2006
Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles
2014
Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species
2008
CD8+ T Cell Tolerance in Nonobese Diabetic Mice Is Restored by Insulin-Dependent Diabetes Resistance Alleles
2005
Genes within the Idd5 and Idd9/11 Diabetes Susceptibility Loci Affect the Pathogenic Activity of B Cells in Nonobese Diabetic Mice
2006
Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses SupportCtla4andNramp1as Candidates forIdd5.1andIdd5.2in the Nonobese Diabetic Mouse
2004