Citation Impact
Citing Papers
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
2019 Science
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
2013
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Review: Role of Blood Platelets in Infection and Inflammation
2002
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
2014
Plasma β-amyloid in Alzheimer’s disease and vascular disease
2016 StandoutNobel
Roles of tau protein in health and disease
2017
Reduction of Brain β-Amyloid (Aβ) by Fluvastatin, a Hydroxymethylglutaryl-CoA Reductase Inhibitor, through Increase in Degradation of Amyloid Precursor Protein C-terminal Fragments (APP-CTFs) and Aβ Clearance
2010
Open questions for Alzheimer’s disease immunotherapy
2014
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
2012
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
2015
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
MicroRNA fingerprints during human megakaryocytopoiesis
2006
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
The Amyloid-β Pathway in Alzheimer’s Disease
2021
Untangling Genetic Risk for Alzheimer’s Disease
2017
The therapeutic potential of interleukin-6 hyperagonists and antagonists
1997
Clearance of amyloid-β by circulating lipoprotein receptors
2007
The death of cardiotonic steroid‐treated cells: evidence of Na+i,K+i‐independent H+i‐sensitive signalling
2006
Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
2013
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
The effect of age and gender on bladder cancer: a critical review of the literature
2009
Identification of digitalis‐like compounds in human cataractous lenses
1993
Smooth muscle of the bladder in the normal and the diseased state: Pathophysiology, diagnosis and treatment
1997
Huntington's disease
2007 Standout
Advances in hematopoietic stem cell culture
1998
From Threat to Fear: The Neural Organization of Defensive Fear Systems in Humans
2009 StandoutNobel
Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes
2012
Marine natural products
1990 Standout
Digitalis-like compounds and Na + , K + -ATPase activity in bovine lens
1997
Marine natural products
2011
Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4
1996 Standout
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
2015
Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury
2011
Mechanisms of Protein Seeding in Neurodegenerative Diseases
2012
Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight
2018
Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain
2010
Na,K-ATPase Inhibitors from Bovine Hypothalamus and Human Plasma Are Different from Ouabain: Nanogram Scale CD Structural Analysis
1995
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation
1998
Gene delivery by lentivirus vectors
2007
An ionizable lipid toolbox for RNA delivery
2021 StandoutNobel
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Tau in physiology and pathology
2015 Standout
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
2015
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Conotoxins down under
2006
Motor and cognitive deficits in aged tau knockout mice in two background strains
2014
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Upscaling of lentiviral vector production by tangential flow filtration
2005
The Cellular Phase of Alzheimer’s Disease
2016
The versatility and universality of calcium signalling
2000 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo–pituitary–adrenocortical responsiveness
2003
Endogenous cardiac glycosides, a new class of steroid hormones
2002
Diabetic Retinopathy
2012 Standout
Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
2012
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
2007 Standout
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
A bioactive designer cytokine for human hematopoietic progenitor cell expansion
1997
Bladder cancer
2016 Standout
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Stress and the brain: from adaptation to disease
2005 Standout
Bovine adrenals and hypothalamus are a major source of proscillaridin A- and ouabain-immunoreactivities
1998
The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants
2017 Standout
Intravesical chemotherapy prophylaxis in primary superficial bladder cancer
2000
The Glymphatic System: A Beginner’s Guide
2015 Standout
Alzheimer's disease
2016 Standout
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
2017
Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease
2009
Antibody Therapeutics Targeting Aβ and Tau
2017
Cardiotonic steroids on the road to anti-cancer therapy
2007
Magnesium regulates intracellular free ionized calcium concentration and cell geometry in vascular smooth muscle cells
1992
Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis
2014
Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
2014
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
MicroRNA signatures in human cancers
2006 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Biomarkers of Traumatic Injury Are Transported from Brain to Blood via the Glymphatic System
2015
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury
2014
Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
2014
Reassessment of Exosome Composition
2019 Standout
The road to restoring neural circuits for the treatment of Alzheimer's disease
2016 Nature
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Tau Kinetics in Neurons and the Human Central Nervous System
2018
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Time-tagged ticker tapes for intracellular recordings
2023 StandoutNobel
Na + pump low and high ouabain affinity α subunit isoforms are differently distributed in cells
1997
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Lecanemab in Early Alzheimer’s Disease
2022 Standout
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells
2005
Self-Assembled Monolayers of Thiolates on Metals as a Form of Nanotechnology
2005 Standout
Tau reduction prevents disease in a mouse model of D ravet syndrome
2014
Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis
2012
Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection
2020
Long-term ouabain administration produces hypertension in rats.
1993
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Bladder Cancer
2020 Standout
Guideline for the Management of Nonmuscle Invasive Bladder Cancer (Stages Ta, T1, and Tis): 2007 Update
2007
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
2017
Anti‐tau antibody reduces insoluble tau and decreases brain atrophy
2015
Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels
2017
Mass spectral characterization of an endogenous digitalislike factor from human plasma.
1991
Bifidobacterium and enteral feeding in preterm infants: Cluster‐randomized trial
2014
Identification of two cardiac glycosides as Na(+)-pump inhibitors in rat urine and diet.
1994
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo
2003
Nitrogenous sesquiterpenes from the Thai marine sponge Halichondria sp.
2011
Identification and characterization of a ouabain-like compound from human plasma.
1991
Orientational Behavior of Thermotropic Liquid Crystals on Surfaces Presenting Electrostatically Bound Vesicular Stomatitis Virus
2004
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Impaired Lipoprotein Receptor-Mediated Peripheral Binding of Plasma Amyloid-β is an Early Biomarker for Mild Cognitive Impairment Preceding Alzheimer's Disease
2011
Whole Structure−Activity Relationships of the Fat-Accumulation Inhibitor (−)-Ternatin: Recognition of the Importance of Each Amino Acid Residue
2008
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease
2015
Effect of 1 Night of Total Sleep Deprivation on Cerebrospinal Fluid β-Amyloid 42 in Healthy Middle-Aged Men
2014
Sodium/Calcium Exchange: Its Physiological Implications
1999 Standout
Culture-Induced Changes in Blood—Brain Barrier Transcriptome: Implications for Amino-Acid Transporters in vivo
2009
Physiological effects of endogenous ouabain: control of intracellular Ca2+ stores and cell responsiveness
1993
Works of Kaoru Yamada being referenced
The Low Density Lipoprotein Receptor-related Protein 1 Mediates Uptake of Amyloid β Peptides in an in Vitro Model of the Blood-Brain Barrier Cells
2008
Upregulation of Polymeric Immunoglobulin Receptor Expression by the Heat‐Inactivated Potential Probiotic Bifidobacterium bifidum OLB6378 in a Mouse Intestinal Explant Model
2011
Convergent synthesis and in vivo inhibitory effect on fat accumulation of (−)-ternatin, a highly N-methylated cyclic peptide
2007
Purification of Endogenous Digitalis-Like Factors from Normal Human Urine
1998
Modulation of the levels of ouabain‐like compound by central catecholamine neurons in rats
1995
Isolation of a urinary digitalis-like factor indistinguishable from digoxin
1990
Halichlorine is a novel L-type Ca2+ channel inhibitor isolated from the marine sponge Halichondria okadai Kadota
2009
Ouabain-like factor
1998
Aβ Immunotherapy: Intracerebral Sequestration of Aβ by an Anti-Aβ Monoclonal Antibody 266 with High Affinity to Soluble Aβ
2009
Immunohistochemical mapping of nitric oxide synthase in the rat hypothalamus and colocalization with neuropeptides
1996
Antisense Reduction of Tau in Adult Mice Protects against Seizures
2013
Purification and characterization of human urine-derived digitalis-like factor
1988
Existence of a polar digitalis-like factor in mammalian hypothalamus
1989
Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model
2015
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier
2007
Major Involvement of Low-Density Lipoprotein Receptor-Related Protein 1 in the Clearance of Plasma Free Amyloid β-Peptide by the Liver
2006
Prophylactic treatment for superficial bladder cancer following transurethral resection
1987
Functional Correction of Fanconi Anemia Group C Hematopoietic Cells by the Use of a Novel Lentiviral Vector
2001
Thrombopoietin‐independent effect of interferon‐γ on the proliferation of human megakaryocyte progenitors
1997
Extracellular α-synuclein levels are regulated by neuronal activity
2018
Modulation of vascular calcium channel activity in response to acute volume expansion in rats
1995
In VivoMicrodialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
2011
Presence of digitalis-like factor in mammalian plasma
1988
Analysis of in vivo turnover of tau in a mouse model of tauopathy
2015
Neuronal activity regulates extracellular tau in vivo
2014
Effect of sex hormones on development of urinary bladder tumours in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine
1975
An autopsy case with clinically and molecular genetically diagnosed Huntington's disease with only minimal non-specific neuropathological findings.
2000
[Effects of long-term administration of oxybutynin hydrochloride (KL007) for the treatment of neurogenic bladder and unstable bladder].
1989
Analysis of interleukin 6 receptor and gp130 expressions and proliferative capability of human CD34+ cells.
1996
Soluble Interleukin-6 (IL-6) Receptor With IL-6 Stimulates Megakaryopoiesis From Human CD34+ Cells Through Glycoprotein (gp)130 Signaling
1999
Homocereulide, an Extremely Potent Cytotoxic Depsipeptide from the Marine Bacterium Bacillus cereus
1995
Urinary sodium pump inhibitor raises cytosolic free calcium concentration in rat aorta.
1989
Lentivirus Vector Purification Using Anion Exchange HPLC Leads to Improved Gene Transfer
2003
Neuronal activity regulates extracellular tau in vivo
2014