Citation Impact
Citing Papers
The Homeobox Gene Caudal Regulates Constitutive Local Expression of Antimicrobial Peptide Genes in Drosophila Epithelia
2003
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
MicroRNAs Regulate Brain Morphogenesis in Zebrafish
2005 Science
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans
2006 StandoutScienceNobel
Caspase-mediated processing of the Drosophila NF-κB factor Relish
2003
Prevalence of Local Immune Response against Oral Infection in a Drosophila/Pseudomonas Infection Model
2006
The LARK RNA-Binding Protein Selectively Regulates the Circadian Eclosion Rhythm by Controlling E74 Protein Expression
2007
Two Proteases Defining a Melanization Cascade in the Immune System of Drosophila
2006
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective
2002
A Ubiquitin-Proteasome Pathway Represses the Drosophila Immune Deficiency Signaling Cascade
2002
Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome
1997
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
2005
MicroRNAs
2004 Standout
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
2004 Standout
Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
2004 StandoutNobel
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
2001
Sensing of Gram‐positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP‐SA
2006
Structural and biochemical studies of retroviral proteases
2000
Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning
1998 StandoutNobel
Sensing and signaling during infection in Drosophila
2004 StandoutNobel
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Functional Dissection of an Innate Immune Response by a Genome-Wide RNAi Screen
2004
Asymmetry in the Assembly of the RNAi Enzyme Complex
2003 Standout
In vitro analysis of RNA interference in Drosophila melanogaster
2003
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
The C-terminal cytoplasmic Lys-Thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling
2000
Post-transcriptional gene silencing by double-stranded RNA
2001
Structural Basis for Preferential Recognition of Diaminopimelic Acid-type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins
2006
Planting the seed: target recognition of short guide RNAs
2014
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
The Drosophila Inhibitor of Apoptosis (IAP) DIAP2 Is Dispensable for Cell Survival, Required for the Innate Immune Response to Gram-negative Bacterial Infection, and Can Be Negatively Regulated by the Reaper/Hid/Grim Family of IAP-binding Apoptosis Inducers
2006
The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila
2006
Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing
2005
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Killing the messenger: short RNAs that silence gene expression
2003
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
2004
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
A Model of Bacterial Intestinal Infections in Drosophila melanogaster
2007 StandoutNobel
A Drosophila Pattern Recognition Receptor Contains a Peptidoglycan Docking Groove and Unusual L,D-Carboxypeptidase Activity
2004 Nobel
Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9
2017
Drosophila immunity: paths and patterns
2003
The immune response of Drosophila
2003 StandoutNatureNobel
RISC Assembly Defects in the Drosophila RNAi Mutant armitage
2004
Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
2005
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
2005 StandoutNature
RNA Interference and Small Interfering RNAs
2001
The Exosome Regulates Circadian Gene Expression in a Posttranscriptional Negative Feedback Loop
2009
Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting
1989 StandoutNatureNobel
Molecular analysis of large transposable elements carrying the white locus of Drosophila melanogaster
1983
Drosophila Immunity: A Large-Scale In Vivo RNAi Screen Identifies Five Serine Proteases Required for Toll Activation
2006
Immune Activation of NF-κB and JNK Requires Drosophila TAK1
2003
Targeting of TAK1 by the NF-κB protein Relish regulates the JNK-mediated immune response in Drosophila
2004
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 StandoutNobel
Crystal Structure of the Drosophila Peptidoglycan Recognition Protein (PGRP)-SA at 1.56 Å Resolution
2004
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Downregulation of the Drosophila Immune Response by Peptidoglycan-Recognition Proteins SC1 and SC2
2006 StandoutNobel
Revealing the world of RNA interference
2004 StandoutNatureNobel
Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing
2017
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
The road to Toll
2004
The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila
2005 StandoutNobel
The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation
2006
Inhibitor of apoptosis 2 and TAK1‐binding protein are components of the Drosophila Imd pathway
2005
The Drosophila Amidase PGRP-LB Modulates the Immune Response to Bacterial Infection
2006
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
The functions of animal microRNAs
2004 StandoutNatureNobel
Perspective: machines for RNAi
2005
Mouse period 2 mRNA circadian oscillation is modulated by PTB–mediated rhythmic mRNA degradation
2008
The Role of Ubiquitination in Drosophila Innate Immunity
2005
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway
2005
The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila
2005
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
2003
Replication-competent Moloney murine leukemia virus carrying a bacterial suppressor tRNA gene: selective cloning of proviral and flanking host sequences.
1985
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus
1985
Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems
1993 Standout
Genome organization and transactivation of the human immunodeficiency virus type 2
1987 StandoutNatureNobel
Dynamic analysis of larval locomotion in Drosophila chordotonal organ mutants
2003
Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites
1987
Role of reverse transcription in the generation of extrachromosomal copia mobile genetic elements
1984 Nature
Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.
1984
Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
2004
Isolation of a New Human Retrovirus from West African Patients with AIDS
1986 StandoutScienceNobel
Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage
2008
Immunology: Approaches to AIDS therapy
1986 StandoutNatureNobel
Pathway Specificity by the Bifunctional Receptor Frizzled Is Determined by Affinity for Wingless
2000
Molecular Genetics of the Bithorax Complex in Drosophila melanogaster
1983 StandoutScienceNobel
Correct integration of retroviral DNA in vitro
1987 StandoutNobel
Molecular biology: Reverse transcriptase rides again
1985 StandoutNatureNobel
Circadian Amplitude of Cryptochrome 1 Is Modulated by mRNA Stability Regulation via Cytoplasmic hnRNP D Oscillation
2009
A Spätzle-Processing Enzyme Required for Toll Signaling Activation in Drosophila Innate Immunity
2006
Caspar, a suppressor of antibacterial immunity in Drosophila
2006
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
2001
Involvement of nucleocapsids in reverse transcription: a general phenomenon?
1987
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
1986 StandoutNatureNobel
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
RNA Silencing in Plants--Defense and Counterdefense
2001 Science
Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome.
1983
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.
1993
Viruses in Human Cancers
1991 StandoutScienceNobel
The Drosophila Inhibitor of Apoptosis Protein DIAP2 Functions in Innate Immunity and Is Essential To Resist Gram-Negative Bacterial Infection
2006
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Toll and IMD Pathways Synergistically Activate an Innate Immune Response in Drosophila melanogaster
2007
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
2003
Peptidoglycan Molecular Requirements Allowing Detection by the Drosophila Immune Deficiency Pathway
2004
Isolation and characterization of a hepatitis B virus endemic in herons
1988
Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro
2005
Use and Abuse of RNAi to Study Mammalian Gene Function
2012 StandoutScienceNobel
Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
2005
Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease
1989 Science
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Expression of the Rous Sarcoma Virus pol Gene by Ribosomal Frameshifting
1985 StandoutScienceNobel
Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors.
1984
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Drosophila : The Genetics of Innate Immune Recognition and Response
2004
Mutants and pseudorevertants of moloney murine leukemia virus with alterations at the integration site
1985
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
A retrovirus-like strategy for expression of a fusion protein encoded by yeast transposon Ty1
1985 Nature
RNA viruses: Reverse transcription in plants?
1983 Nature
LAV Revisited: Origins of the Early HIV-1 Isolates from Institut Pasteur
1991 StandoutScienceNobel
Morphogen gradient interpretation
2001 StandoutNatureNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Ty elements transpose through an RNA intermediate
1985
Works of Kaoru Saigo being referenced
Transcriptional regulation ofatonalrequired forDrosophilalarval eye development by concerted action of Eyes absent, Sine oculis and Hedgehog signaling independent of Fused kinase and Cubitus interruptus
2000
Identification of seven novel protein‐tyrosine kinase genes of Drosophila by the polymerase chain reaction
1991
Homodimeric Structure and Double-stranded RNA Cleavage Activity of the C-terminal RNase III Domain of Human Dicer
2007
Requirements of DFR1/Heartless, a mesoderm-specific Drosophila FGF-receptor, for the formation of heart, visceral and somatic muscles, and ensheathing of longitudinal axon tracts in CNS
1997
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian Cells Requires Dicer and eIF2C Translation Initiation Factors
2003
In Vivo RNA Interference Analysis Reveals an Unexpected Role for GNBP1 in the Defense against Gram-positive Bacterial Infection in Drosophila Adults
2004
Inducible Expression of Double-Stranded RNA Reveals a Role for dFADD in the Regulation of the Antibacterial Response in Drosophila Adults
2002
Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect
2008
Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect
2008
Distinct expression of two Drosophila homologs of fibroblast growth factor receptors in imaginai discs
1993
Crystal structure of the PIN domain of human telomerase‐associated protein EST1A
2007
Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
2000
Retrovirus-like features and site specific insertions of a transposable element, tom, in Drosophila ananassae
1988
The nucleotide sequences of copia and copia-related RNA in Drosophila virus-like particles
1985 Nature
Close relationship between the long terminal repeats of avian leukosis-sarcoma virus and copia-like movable genetic elements of Drosophila.
1983
Retrovirus-like particles containing RNA homologous to the transposable element copia in Drosophila melanogaster
1983 Nature
Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus.
1985
Insertion of a movable genetic element, 297, into the T-A-T-A box for the H3 histone gene in Drosophila melanogaster.
1982
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1
2007
Acopiaprimer pseudogene possibly generated by an aberrant reverse transcription of acopiarelated element inDrosophila
1986
Identification of the coding sequence for a reverse transcriptase-like enzyme in a transposable genetic element in Drosophila melanogaster
1984 Nature
Retroviral protease-like sequence in the yeast transposon Ty 1
1985 Nature
Sequence-specific insertion of the Drosophila transposable genetic element 17.6
1984 Nature
Identification of genes for reverse transcriptase–like enzymes in twoDrosophilaretrotransposons,412 and gypsy; a rapid detection method of reverse transcriptase genes using YXDD box probes
1986
Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants
1999