Citation Impact
Citing Papers
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Topographical and Temporal Diversity of the Human Skin Microbiome
2009 StandoutScience
Identification and characterization of essential genes in the human genome
2015 Science
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Stat3 regulates genes common to both wound healing and cancer
2005
DNA damage checkpoints: from initiation to recovery or adaptation
2007
Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation
2006
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
Common fragile sites
2003
Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
2005
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
mTOR Signaling in Growth Control and Disease
2012 Standout
Involvement of the TRAP220 Component of the TRAP/SMCC Coactivator Complex in Embryonic Development and Thyroid Hormone Action
2000
Necroptosis and its role in inflammation
2015 StandoutNature
ATR Regulates Fragile Site Stability
2002
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
2003 StandoutNature
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
2006
Pathogenesis and clinical features of psoriasis
2007 Standout
The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partners
2008
The mTOR pathway and its role in human genetic diseases
2008
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Akt-regulated pathways in prostate cancer
2005
Wound repair and regeneration
2008 StandoutNature
Tuberin Regulates p70 S6 Kinase Activation and Ribosomal Protein S6 Phosphorylation
2002
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
The NF-κB-independent functions of IKK subunits in immunity and cancer
2009
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
2009
Mechanisms of Disease: insights into the emerging role of signal transducers and activators of transcription in cancer
2005
Lack of toxicity of a STAT3 decoy oligonucleotide
2008
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
2005 Nature
Hypoxia regulates TSC1/2–mTOR signaling and tumor suppression through REDD1-mediated 14–3–3 shuttling
2008
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling
2006
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Choreographing Immunity in the Skin Epithelial Barrier
2019
Getting under the skin: the immunogenetics of psoriasis
2005
The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development
2008
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
2012
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Targeted Disruption of Glutathione Peroxidase 4 in Mouse Skin Epithelial Cells Impairs Postnatal Hair Follicle Morphogenesis that Is Partially Rescued through Inhibition of COX-2
2013
Epidermal barrier formation and recovery in skin disorders
2006
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Defining the mode of tumour growth by clonal analysis
2012 Nature
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Oncogenic stress sensed by the immune system: role of natural killer cell receptors
2009
Stress and mTORture signaling
2006
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
2010
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
STAT3 Activation Regulates Growth, Inflammation, and Vascularization in a Mouse Model of Gastric Tumorigenesis
2006
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
2009 Standout
Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway
2009
Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer
2009
Molecular mechanisms of cancer development in obesity
2011
Inflammation and Cancer: Is the Link as Simple as We Think?
2005
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Crosstalk in NF-κB signaling pathways
2011 Standout
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR
2007
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Cancer-related inflammation
2008 StandoutNature
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Molecular mechanisms of mTOR-mediated translational control
2009 Standout
Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis
2012
Cellular senescence: hot or what?
2009
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
The role of protein kinase C δ activation and STAT3 Ser727 phosphorylation in insulin-induced keratinocyte proliferation
2006
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
2009
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation.
2003 StandoutNobel
Malignant transformation in a nontumorigenic human prostatic epithelial cell line.
2001
Transcriptional Control of Wound Repair
2007
Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3
2007
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Links between α-catenin, NF-κB, and squamous cell carcinoma in skin
2006
Critical roles for the TSC-mTOR pathway in β-cell function
2009
The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
2008 Standout
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Cyclooxygenase-2-Dependent Activation of Signal Transducer and Activator of Transcription 3 by Interleukin-6 in Non–Small Cell Lung Cancer
2005
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Conformationally Constrained Peptidomimetic Inhibitors of Signal Transducer and Activator of Transcription 3: Evaluation and Molecular Modeling
2009
mTOR Pathway as a Target in Tissue Hypertrophy
2006
Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors
1993
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
Works of Kaoru Kiguchi being referenced
Progressive Metaplastic and Dysplastic Changes in Mouse Pancreas Induced by Cyclooxygenase-2 Overexpression
2008
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
1997
Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications
2009
Tuberin-Dependent Membrane Localization of Polycystin-1
2001
Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A
1992
Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
2004
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
2004
IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer
2008
WWOX, the FRA16D gene, behaves as a suppressor of tumor growth.
2001
Signal Transducer and Activator of Transcription 3 Is a Key Regulator of Keratinocyte Survival and Proliferation following UV Irradiation
2005
Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein.
1990
Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.
2002
Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion.
2000
Differential induction of apoptosis in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A.
1994
Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
2004
Epidermal Growth Factor Receptor-Mediated Activation of Stat3 during Multistage Skin Carcinogenesis
2004
ATM promotes apoptosis and suppresses tumorigenesis in response to Myc
2006
Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice
2000
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
2006