Citation Impact
Citing Papers
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
2006
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Ubiquitin-binding domains
2006
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor
2010
Ufd1 Exhibits the AAA-ATPase Fold with Two Distinct Ubiquitin Interaction Sites
2005
Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
2017
Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T
2008
PIAS proteins: pleiotropic interactors associated with SUMO
2009
Ubiquitin-binding domains — from structures to functions
2009
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Systems Biology of Growth Factor‐Induced Receptor Endocytosis
2008
Ubiquitin-dependent Proteolytic Control of SUMO Conjugates
2007
Specificity in Signal Transduction
2004
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
2004
A Role for Ubiquitin in Selective Autophagy
2009
SUMO‐targeted ubiquitin ligases in genome stability
2007
Lysosomes: fusion and function
2007 Standout
Structure of the Small Ubiquitin-like Modifier (SUMO)-interacting Motif of MBD1-containing Chromatin-associated Factor 1 Bound to SUMO-3
2008
LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
2012
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
2010
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
2006
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
2008
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
The LC3 interactome at a glance
2013
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Direct Binding of CoREST1 to SUMO-2/3 Contributes to Gene-Specific Repression by the LSD1/CoREST1/HDAC Complex
2009
Autophagy regulates lipid metabolism
2009 StandoutNature
Dynamic control of signaling by modular adaptor proteins
2007
Lineage dependency and lineage-survival oncogenes in human cancer
2006
A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity
2010
Intra-endosomal membrane traffic
2006
E3-Independent Monoubiquitination of Ubiquitin-Binding Proteins
2007
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
2009 Nature
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Atg8‐family interacting motif crucial for selective autophagy
2010 StandoutNobel
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
Principles of ubiquitin and SUMO modifications in DNA repair
2009 Nature
The cullin protein family
2011
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics
2005
Network organization of the human autophagy system
2010 StandoutNature
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling
2008
Role of ubiquitin- and Ubl-binding proteins in cell signaling
2007
The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
2007 StandoutNobel
Flotillins and the PHB Domain Protein Family: Rafts, Worms and Anaesthetics
2005
Structural basis for regulation of poly‐SUMO chain by a SUMO‐like domain of Nip45
2009
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Signaling from endosomes: Location makes a difference
2008
Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins
2007
The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines
2010
Reading protein modifications with interaction domains
2006
A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle
2004
Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis
2006
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
2006
Linkage-Specific Avidity Defines the Lysine 63-Linked Polyubiquitin-Binding Preference of Rap80
2009
Evidence for Bidentate Substrate Binding as the Basis for the K48 Linkage Specificity of Otubain 1
2009
A SIM-ultaneous role for SUMO and ubiquitin
2008
Endocytosis: the DUB version
2006
Endocytosis and intracellular trafficking of ErbBs
2008
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching
2007
Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation
2008
The Yeast Hex3·Slx8 Heterodimer Is a Ubiquitin Ligase Stimulated by Substrate Sumoylation
2007
Human Growth Hormone-regulated HOXA1 Is a Human Mammary Epithelial Oncogene
2003
Differential Regulation of EGF Receptor Internalization and Degradation by Multiubiquitination within the Kinase Domain
2006
Proteolytic and lipolytic responses to starvation
2006
Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling
2009
Small Ubiquitin-related Modifier (SUMO) Binding Determines Substrate Recognition and Paralog-selective SUMO Modification
2008
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25
2008
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
α-Synuclein and Parkin Contribute to the Assembly of Ubiquitin Lysine 63-linked Multiubiquitin Chains
2005
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
The ubiquitous role of ubiquitin in the DNA damage response
2010
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
E3 ubiquitin ligases as T cell anergy factors
2004
Ubc9 Sumoylation Regulates SUMO Target Discrimination
2008
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
2008
An extended consensus motif enhances the specificity of substrate modification by SUMO
2006
Sprouty proteins, masterminds of receptor tyrosine kinase signaling
2008
Global quantification of mammalian gene expression control
2011 StandoutNature
Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway
2007
Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway
2008
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Concepts in sumoylation: a decade on
2007
The Structure and Conformation of Lys63-Linked Tetraubiquitin
2009
Regulation of death receptor signaling by the ubiquitin system
2009
Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1
2009
The plant immune system
2006 StandoutNature
Strigolactone inhibition of shoot branching
2008 StandoutNature
Regulation of ubiquitin-binding proteins by monoubiquitination
2006
EGF receptor ubiquitination is not necessary for its internalization
2007
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Mechanism of Divergent Growth Factor Effects in Mesenchymal Stem Cell Differentiation
2005 Science
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
2015 StandoutScience
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling
2007 Science
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
2008 StandoutScience
B Cell Signaling and Fate Decision
2009
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Getting into position: the catalytic mechanisms of protein ubiquitylation
2004
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
SUMO junction—what's your function?
2007
Biogenesis and Function of Multivesicular Bodies
2007
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
MIB-1 Is Required for Spermatogenesis and Facilitates LIN-12 and GLP-1 Activity inCaenorhabditis elegans
2018
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
2009
The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases,
2005
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Modification of Proteins by Ubiquitin and Ubiquitin-Like Proteins
2006
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
Depletion of TSG101 forms a mammalian `Class E' compartment: a multicisternal early endosome with multiple sorting defects
2005
RING Domain E3 Ubiquitin Ligases
2009 Standout
AMSH is an endosome-associated ubiquitin isopeptidase
2004
Functional Roles of Ubiquitin-Like Domain (ULD) and Ubiquitin-Binding Domain (UBD) Containing Proteins
2009
A Tale of Two Cbls: Interplay of c-Cbl and Cbl-b in Epidermal Growth Factor Receptor Downregulation
2008
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
2006
Regulation of Epidermal Growth Factor Receptor Down-Regulation by UBPY-mediated Deubiquitination at Endosomes
2005
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
The SUMO E3 Ligase Activity of Pc2 Is Coordinated through a SUMO Interaction Motif
2010
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
The Ubiquitin Code
2012 Standout
High-Throughput Cloning of Temperature-Sensitive Caenorhabditis elegans Mutants with Adult Syncytial Germline Membrane Architecture Defects
2015
Ubiquitin-Binding Domains in Y-Family Polymerases Regulate Translesion Synthesis
2005 Science
Structural Mechanisms Underlying Posttranslational Modification by Ubiquitin-Like Proteins
2007
Seven-Transmembrane Receptors and Ubiquitination
2007
Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated Nuclear Receptor Ad4BP/SF-1
2009
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Works of Kaisa Haglund being referenced
Specification of SUMO1- and SUMO2-interacting Motifs
2006
Identification of a Novel Proline-Arginine Motif Involved in CIN85-dependent Clustering of Cbl and Down-regulation of Epidermal Growth Factor Receptors
2003
Ubiquitylation and cell signaling
2005
Homeobox gene Cdx1 regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells
2001
Distinct monoubiquitin signals in receptor endocytosis
2003
Aberrant Receptor Signaling and Trafficking as Mechanisms in Oncogenesis
2007
Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth
2009
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
2003
Investigating spermatogenesis in Drosophila melanogaster
2014
Suppressors of T-cell Receptor Signaling Sts-1 and Sts-2 Bind to Cbl and Inhibit Endocytosis of Receptor Tyrosine Kinases
2004
ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo
2015
Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors
2002
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development.
2011
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
2004
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
2011
The role of ubiquitylation in receptor endocytosis and endosomal sorting
2012
Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
2005