Kaige Yan

Human mitochondrial protein complexes revealed by large-scale coevolution analysis and deep learning-based structure modeling

Structure of the nuclear exosome captured on a maturing preribosome

Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism

Protein interactions in human pathogens revealed through deep learning

Mechanisms, regulation and functions of the unfolded protein response

Mammalian Mitochondrial Complex I Structure and Disease-Causing Mutations

The role of RNase R in trans-translation and ribosomal quality control

Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM

NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly

Macrophages in immunoregulation and therapeutics

A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM

Advances in the field of single-particle cryo-electron microscopy over the last decade

Leveraging crosslinking mass spectrometry in structural and cell biology

Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

Time-resolved cryo-electron microscopy: Recent progress

NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4 mice and Leigh syndrome patients: A stabilizing role for NDUFAF2

In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes

Mitochondrial Respiratory Chain Complexes

Structural and mutational analysis of the ribosome-arresting human XBP1u

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Determination of the ribosome structure to a resolution of 2.5 Å by single‐particle cryo‐EM

Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit

Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes

The architecture of the mammalian respirasome

Structural insights into the assembly of the 30S ribosomal subunit in vivo: functional role of S5 and location of the 17S rRNA precursor sequence

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome

Mechanisms of ribosome stalling by SecM at multiple elongation steps