Citation Impact
Citing Papers
Identification of factors required for m 6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI
2017
Spatially resolved, highly multiplexed RNA profiling in single cells
2015 StandoutScience
N6-Methyladenosine Modulates Nonsense-Mediated mRNA Decay in Human Glioblastoma
2019
RepeatModeler2 for automated genomic discovery of transposable element families
2020 Standout
Single-base mapping of m 6 A by an antibody-independent method
2019
SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells
2017
RNA modifications modulate gene expression during development
2018 Science
The emerging biology of RNA post-transcriptional modifications
2016
N 6 ‐Methyladenosine‐Sensitive RNA‐Cleaving Deoxyribozymes
2018
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence
2017
Nitro-fatty Acid Formation and Signaling
2008
Epidemic Inflammation: Pondering Obesity
2008
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3
2019
The Role of m6A/m-RNA Methylation in Stress Response Regulation
2018
The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells
2019
MicroRNA-145 Modulates N6-Methyladenosine Levels by Targeting the 3′-Untranslated mRNA Region of the N6-Methyladenosine Binding YTH Domain Family 2 Protein
2017
Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo
2019
Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets
2018
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
2018
METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma
2019
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein–RNA Interactome
2017
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1
2017
The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway
2019
The role of m6A RNA methylation in human cancer
2019 Standout
Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression
2018
N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
2020 Science
N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer
2019
Identifying sequence features that drive ribosomal association for lncRNA
2018
Looping Back to Leap Forward: Transcription Enters a New Era
2014
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112
2019
Engineering precision nanoparticles for drug delivery
2020 Standout
The embryo as a laboratory: quantifying transcription in Drosophila
2014
The Many Faces of PPARγ
2005
Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis
2017
m6A modification controls the innate immune response to infection by targeting type I interferons
2018
Extensive translation of circular RNAs driven by N6-methyladenosine
2017
ALKBH1-Mediated tRNA Demethylation Regulates Translation
2016
The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′–3′ exoribonuclease XRN1
2018
N6-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics
2016
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
2018
m6AVar: a database of functional variants involved in m6A modification
2017
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
2017
Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
2017
N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
2016
Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression
2016
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis
2019
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
2017
Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins
2015
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis
2019
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment
2015
Base-resolution models of transcription-factor binding reveal soft motif syntax
2021
YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
2016
N6-Methylated Adenosine in RNA: From Bacteria to Humans
2015
Post-transcriptional gene regulation by mRNA modifications
2016 Standout
Cracking the epitranscriptome
2016
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake
2018 StandoutNobel
A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors
2018
N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection
2016
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
2016
Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
2016
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
2017 Nature
Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells
2016
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner
2019
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
2016
Dynamics of Human and Viral RNA Methylation during Zika Virus Infection
2016
m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome
2016
Interactions, localization, and phosphorylation of the m6A generating METTL3–METTL14–WTAP complex
2018
The Human Transcription Factors
2018 Standout
Regulatory Enhancer–Core-Promoter Communication via Transcription Factors and Cofactors
2016
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice
2004
Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex
2019
Nonresolving Inflammation
2010 Standout
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
2017
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
2018 Standout
Epitranscriptomic influences on development and disease
2017
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells
2019 Nature
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
2017
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Transcriptome-wide high-throughput deep m6A-seq reveals unique differential m6A methylation patterns between three organs in Arabidopsis thaliana
2015
m6A modulates haematopoietic stem and progenitor cell specification
2017 Nature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation
2017
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
2015
Enhancer Control of Transcriptional Bursting
2016
m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
2016 Nature
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts
2018
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
2011
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1
2019
Brain catecholamine metabolism in catechol‐O‐methyltransferase (COMT)‐deficient mice
2002
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
2018
N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
2018
Critical Enzymatic Functions of FTO in Obesity and Cancer
2018
Role of N6-methyladenosine modification in cancer
2017
Neocortical excitation/inhibition balance in information processing and social dysfunction
2011 StandoutNature
Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs
2017
Peroxisome Proliferator‐Activated Receptors in the Modulation of the Immune/Inflammatory Response in Atherosclerosis
2008
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
2015 Standout
Materials for non-viral intracellular delivery of messenger RNA therapeutics
2015
mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
2018 Nature
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
2017
RNA m6A methylation regulates the ultraviolet-induced DNA damage response
2017 Nature
A common class of transcripts with 5′-intron depletion, distinct early coding sequence features, and N 1 -methyladenosine modification
2016
Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior
2010 StandoutNobel
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 Standout
Combinatorial function of transcription factors and cofactors
2017
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
MiR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m6A-caused stabilization of SEC62
2019
5′ UTR m6A Promotes Cap-Independent Translation
2015 Standout
Dynamic m6A mRNA methylation directs translational control of heat shock response
2015 Nature
The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer
2014
RNA N6-methyladenosine modification in cancers: current status and perspectives
2018
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
2017
Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment
2010
N6-Methyladenosine Modification Controls Circular RNA Immunity
2019
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
2017 Nature
Illumina-based RiboMethSeq approach for mapping of 2′-O-Me residues in RNA
2016
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
2020 Standout
Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code
2015
The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
2019
What We Talk About When We Talk About Fat
2014 Standout
The biogenesis, biology and characterization of circular RNAs
2019 Standout
Helraiser intermediates provide insight into the mechanism of eukaryotic replicative transposition
2018
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
2017
The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA
2016 Nature
Regulation of m6A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline
2017
YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma
2018
Reading, writing and erasing mRNA methylation
2019 Standout
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
2019
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma
2019
DART-seq: an antibody-free method for global m6A detection
2019
RNA N 6-Methyladenosine Modification in Normal and Malignant Hematopoiesis
2019
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
2017
Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome
2016
N1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
2015
Probing RNA Modification Status at Single-Nucleotide Resolution in Total RNA
2015
Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex
2016 Nature
m6A RNA methylation promotes XIST-mediated transcriptional repression
2016 Nature
Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation
2019
Exploring the full spectrum of macrophage activation
2008 Standout
The Biogenesis and Precise Control of RNA m6A Methylation
2019
Reading m6A in the Transcriptome: m6A-Binding Proteins
2017
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis
2017
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition
2018
Stearoyl-CoA Desaturase 2 Is Required for Peroxisome Proliferator-activated Receptor γ Expression and Adipogenesis in Cultured 3T3-L1 Cells
2007
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein
2017
Human METTL16 is a N 6 ‐methyladenosine (m 6 A) methyltransferase that targets pre‐mRNAs and various non‐coding RNAs
2017
Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities
2008
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
m6A: Signaling for mRNA splicing
2016
Identification of a selective DNA ligase for accurate recognition and ultrasensitive quantification of N6-methyladenosine in RNA at one-nucleotide resolution
2018
An Elongation‐ and Ligation‐Based qPCR Amplification Method for the Radiolabeling‐Free Detection of Locus‐Specific N6‐Methyladenosine Modification
2018
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication
2018
A catechol- O -methyltransferase that is essential for auditory function in mice and humans
2008 StandoutNobel
N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression
2018
Role of PPARg2 transcription factor in thiazolidinedione-induced insulin sensitization
2011
N6-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression
2016
Rethinking m6A Readers, Writers, and Erasers
2017
Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer
2017
Advances in Biomaterials for Drug Delivery
2018
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Chemical Proteomic Profiling of Human Methyltransferases
2016
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Fat and Beyond: The Diverse Biology of PPARγ
2008 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
Engineering of a DNA Polymerase for Direct m6A Sequencing
2017
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
The Epitranscriptome of Noncoding RNAs in Cancer
2017
Oncogenic Role of an Epigenetic Reader of m6A RNA Modification: YTHDF1 in Merkel Cell Carcinoma
2020
2-Oxoglutarate-Dependent Oxygenases
2018
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
2018
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
2017
PPARs and Lipid Ligands in Inflammation and Metabolism
2011
N6‐Methyladenosine‐Sensitive RNA‐Cleaving Deoxyribozymes
2018
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
m6ASNP: a tool for annotating genetic variants by m6A function
2018
Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N 6 -Adenosine Methylation To Promote Lytic Replication
2017
m6A modulates neuronal functions and sex determination in Drosophila
2016 Nature
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
2017
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N 6‐methyladenosine‐dependent primary MicroRNA processing
2016
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
Structural insights into the molecular mechanism of the m6A writer complex
2016
Precise Antibody-Independent m6A Identification via 4SedTTP-Involved and FTO-Assisted Strategy at Single-Nucleotide Resolution
2018
Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma
2018
Targeted m6A Reader Proteins To Study Epitranscriptomic Regulation of Single RNAs
2018
Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
2015
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline
2017
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Detecting RNA modifications in the epitranscriptome: predict and validate
2017
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
N6-methyladenosine–encoded epitranscriptomics
2016
Works of Kai Chen being referenced
Oncofetal protein IMP3: a new diagnostic biomarker for laryngeal carcinoma
2013
Nucleic Acid Modifications in Regulation of Gene Expression
2016
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Evolution of transcript modification by N6-methyladenosine in primates
2017
High‐Resolution N6‐Methyladenosine (m6A) Map Using Photo‐Crosslinking‐Assisted m6A Sequencing
2014
Characterization of Tumor Suppressive Function of cornulin in Esophageal Squamous Cell Carcinoma
2013
Widespread occurrence ofN6-methyladenosine in bacterial mRNA
2015
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation
2018
Paused Pol II Coordinates Tissue Morphogenesis in the Drosophila Embryo
2013
N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas
2015
Characterization of eukaryotic DNA N6-methyladenine by a highly sensitive restriction enzyme-assisted sequencing
2016
TRF2, but not TBP, mediates the transcription of ribosomal protein genes
2014
Unique features of the m6A methylome in Arabidopsis thaliana
2014
Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation
2015
High‐Resolution N6‐Methyladenosine (m6A) Map Using Photo‐Crosslinking‐Assisted m6A Sequencing
2014
A global change in RNA polymerase II pausing during the Drosophila midblastula transition
2013
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
2005
MAO-A and -B gene knock-out mice exhibit distinctly different behavior.
1999